SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

E4Z9W2

- E4Z9W2_NEIL0

UniProt

E4Z9W2 - E4Z9W2_NEIL0

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Elongation factor Tu
Gene
tuf, NLA_0630, NLA_0810
Organism
Neisseria lactamica (strain 020-06)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi19 – 268GTP By similarityUniRule annotation
Nucleotide bindingi81 – 855GTP By similarityUniRule annotation
Nucleotide bindingi136 – 1394GTP By similarityUniRule annotation

GO - Molecular functioni

  1. GTP binding Source: UniProtKB-HAMAP
  2. GTPase activity Source: InterPro
  3. translation elongation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    Elongation factorUniRule annotationImported

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    GTP-bindingUniRule annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciNLAC489653:GJ91-70-MONOMER.
    NLAC489653:GJ91-89-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Elongation factor TuUniRule annotation
    Short name:
    EF-TuUniRule annotation
    Gene namesi
    Name:tufUniRule annotation
    Ordered Locus Names:NLA_0630Imported, NLA_0810Imported
    OrganismiNeisseria lactamica (strain 020-06)Imported
    Taxonomic identifieri489653 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeNeisseria
    ProteomesiUP000008723: Chromosome

    Subcellular locationi

    Cytoplasm By similarity UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    Complete GO annotation...

    Keywords - Cellular componenti

    CytoplasmUniRule annotation

    Interactioni

    Subunit structurei

    Monomer By similarity.UniRule annotation

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    HOGENOMiHOG000229290.
    KOiK02358.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    HAMAPiMF_00118_B. EF_Tu_B.
    InterProiIPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view]
    PfamiPF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view]
    PRINTSiPR00315. ELONGATNFCT.
    SUPFAMiSSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEiPS00301. EFACTOR_GTP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E4Z9W2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAKEKFERSK PHVNVGTIGH VDHGKTTLTA ALTTILAKKF GGAAKAYDQI    50
    DNAPEEKARG ITINTSHVEY ETETRHYAHV DCPGHADYVK NMITGAAQMD 100
    GAILVCSAAD GPMPQTREHI LLARQVGVPY IIVFMNKCDM VDDAELLELV 150
    EMEIRDLLSS YDFPGDDCPI VQGSALKALE GDAGYEEKIF ELAAALDSYI 200
    PTPERAVDKP FLLPIEDVFS ISGRGTVVTG RVERGVIHVG DEIEIVGLKE 250
    TQKTTCTGVE MFRKLLDEGQ AGDNVGVLLR GTKREEVERG QVLAKPGTIT 300
    PHTKFKAEVY VLSKEEGGRH TPFFANYRPQ FYFRTTDVTG AVTLEEGVEM 350
    VMPGENVTIT VELIAPIAME EGLRFAIREG GRTVGAGVVS SVIA 394
    Length:394
    Mass (Da):42,895
    Last modified:February 8, 2011 - v1
    Checksum:i1441F268DDBEEF15
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FN995097 Genomic DNA. Translation: CBN86307.1.
    FN995097 Genomic DNA. Translation: CBN86325.1.
    RefSeqiWP_013448204.1. NC_014752.1.
    YP_004047703.1. NC_014752.1.
    YP_004047721.1. NC_014752.1.

    Genome annotation databases

    EnsemblBacteriaiCBN86307; CBN86307; NLA_0630.
    CBN86325; CBN86325; NLA_0810.
    GeneIDi10006771.
    10007346.
    KEGGinla:NLA_0630.
    nla:NLA_0810.
    PATRICi45297960. VBINeiLac170077_0081.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FN995097 Genomic DNA. Translation: CBN86307.1 .
    FN995097 Genomic DNA. Translation: CBN86325.1 .
    RefSeqi WP_013448204.1. NC_014752.1.
    YP_004047703.1. NC_014752.1.
    YP_004047721.1. NC_014752.1.

    3D structure databases

    ModBasei Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CBN86307 ; CBN86307 ; NLA_0630 .
    CBN86325 ; CBN86325 ; NLA_0810 .
    GeneIDi 10006771.
    10007346.
    KEGGi nla:NLA_0630.
    nla:NLA_0810.
    PATRICi 45297960. VBINeiLac170077_0081.

    Phylogenomic databases

    HOGENOMi HOG000229290.
    KOi K02358.

    Enzyme and pathway databases

    BioCyci NLAC489653:GJ91-70-MONOMER.
    NLAC489653:GJ91-89-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    HAMAPi MF_00118_B. EF_Tu_B.
    InterProi IPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view ]
    Pfami PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view ]
    PRINTSi PR00315. ELONGATNFCT.
    SUPFAMi SSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEi PS00301. EFACTOR_GTP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Independent evolution of the core and accessory gene sets in the genus Neisseria: insights gained from the genome of Neisseria lactamica isolate 020-06."
      Bennett J.S., Bentley S.D., Vernikos G.S., Quail M.A., Cherevach I., White B., Parkhill J., Maiden M.C.
      BMC Genomics 11:652-652(2010)
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 020-06Imported.

    Entry informationi

    Entry nameiE4Z9W2_NEIL0
    AccessioniPrimary (citable) accession number: E4Z9W2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 8, 2011
    Last sequence update: February 8, 2011
    Last modified: September 3, 2014
    This is version 22 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    External Data

    Dasty 3

    Similar proteinsi