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E4WH56

- E4WH56_RHOE1

UniProt

E4WH56 - E4WH56_RHOE1

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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Rhodococcus equi (strain 103S) (Corynebacterium equi)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Magnesium.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei158 – 1581UniRule annotation
Active sitei593 – 5931UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciREQU685727:GHKP-2134-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
Ordered Locus Names:REQ_22080Imported
OrganismiRhodococcus equi (strain 103S) (Corynebacterium equi)Imported
Taxonomic identifieri685727 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeNocardiaceaeRhodococcus
ProteomesiUP000006892: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000238647.
KOiK01595.
OMAiGIQITIN.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E4WH56-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MMTGTSDSSA ASSVTSAPRA ATEPLRDDIR LLGGILGDIV REQAGEDVFD
60 70 80 90 100
LVERARVESF RVRRSEIDRA ELAELFSTVD TADAIPVIRA FSHFALLANV
110 120 130 140 150
AEDIHRERRR AIHVRAGEPP QDSTLAATYA KLDAAPVDPE IAAGALAGAL
160 170 180 190 200
VAPVITAHPT ETRRRTVFET QNRIMELMRR REWVSVDPAE ADAVDRQLRR
210 220 230 240 250
QILTLWQTAL IRLSRLRIQD EIEVGLRYYD ASLFEVVPRI NAELRDALRS
260 270 280 290 300
RWPDSGVLTE PMLRPGSWIG GDRDGNPYVT ADVVARATHR ASETALEHHL
310 320 330 340 350
AELEVLEREL SMSARLVTVT PELNRLADES GDESAFRADE PYRRAVRGLR
360 370 380 390 400
ARLTGTAARI LGHPAAHAVA GELPDYRDPA ELLADLEIID TSLRSHGDGT
410 420 430 440 450
VADDRLAQLR NSVEVFGFHL CGLDMRQNSE VHETVVAELL AWSGVHPDYA
460 470 480 490 500
SLPEDERVAL LTRELATRRP LAGPHAEFSE LTTKELGILR AAADAVDRIG
510 520 530 540 550
PEAIPNYVIS MCESVSDMLE AAILLAEVGL FDPDGEAGPR CPVGIVPLFE
560 570 580 590 600
TIEDLRHGAE TLTATLDVPL YRALVANRGD SQEVMLGYSD SNKDGGYLAA
610 620 630 640 650
NWALYRAELD LVRVAREKGI RLRLFHGRGG TVGRGGGPSY DAILAQPPGA
660 670 680 690 700
VEGSLRITEQ GEIIAAKYAE PRLARRNLEA LVSATLESTL LDVEGLGDDA
710 720 730 740 750
APAYAVLDEL AELARVAYAD LVHDTPGFVE YFEASTPVAE IGALNIGSRP
760 770 780 790 800
ASRKQTQSIS DLRAIPWVLS WSQSRVMLPG WYGTGTAFEK WVGDDAGRLA
810 820 830 840 850
TLTDLYERWP FFRTVLSNMA QVLSKSDMGL AARYSELVPD AELREEVFGK
860 870 880 890 900
ISAEHARTLA MYRAVTGHDN LLWDNPALDR SVHNRFPYLE PLNHLQVELL
910 920 930
RRYRAGDDSD NVRRGIQLTM NGLATALRNS G
Length:931
Mass (Da):102,310
Last modified:February 8, 2011 - v1
Checksum:i65E97218CAD1F0A1
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FN563149 Genomic DNA. Translation: CBH48261.1.
RefSeqiYP_004006945.1. NC_014659.1.

Genome annotation databases

EnsemblBacteriaiCBH48261; CBH48261; REQ_22080.
GeneIDi9964876.
KEGGireq:REQ_22080.
PATRICi42661839. VBIRhoEqu141084_2204.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FN563149 Genomic DNA. Translation: CBH48261.1 .
RefSeqi YP_004006945.1. NC_014659.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CBH48261 ; CBH48261 ; REQ_22080 .
GeneIDi 9964876.
KEGGi req:REQ_22080.
PATRICi 42661839. VBIRhoEqu141084_2204.

Phylogenomic databases

HOGENOMi HOG000238647.
KOi K01595.
OMAi GIQITIN.

Enzyme and pathway databases

BioCyci REQU685727:GHKP-2134-MONOMER.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 103SImported.

Entry informationi

Entry nameiE4WH56_RHOE1
AccessioniPrimary (citable) accession number: E4WH56
Entry historyi
Integrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: October 1, 2014
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3