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E4WH56

- E4WH56_RHOE1

UniProt

E4WH56 - E4WH56_RHOE1

Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Rhodococcus equi (strain 103S) (Corynebacterium equi)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 22 (01 Oct 2014)
      Sequence version 1 (08 Feb 2011)
      Previous versions | rss
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    Functioni

    Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

    Catalytic activityi

    Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

    Cofactori

    Magnesium.UniRule annotationSAAS annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei158 – 1581UniRule annotation
    Active sitei593 – 5931UniRule annotation

    GO - Molecular functioni

    1. magnesium ion binding Source: UniProtKB-HAMAP
    2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. carbon fixation Source: UniProtKB-HAMAP
    2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
    3. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    LyaseUniRule annotationSAAS annotation

    Keywords - Biological processi

    Carbon dioxide fixationUniRule annotationSAAS annotation

    Keywords - Ligandi

    MagnesiumUniRule annotationSAAS annotation, PyruvateImported

    Enzyme and pathway databases

    BioCyciREQU685727:GHKP-2134-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
    Short name:
    PEPCUniRule annotation
    Short name:
    PEPCaseUniRule annotation
    Gene namesi
    Name:ppcUniRule annotationImported
    Ordered Locus Names:REQ_22080Imported
    OrganismiRhodococcus equi (strain 103S) (Corynebacterium equi)Imported
    Taxonomic identifieri685727 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeNocardiaceaeRhodococcus
    ProteomesiUP000006892: Chromosome

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotation

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PEPCase type 1 family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000238647.
    KOiK01595.
    OMAiGIQITIN.

    Family and domain databases

    HAMAPiMF_00595. PEPcase_type1.
    InterProiIPR021135. PEP_COase.
    IPR018129. PEP_COase_AS.
    IPR022805. PEP_COase_bac/pln-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view]
    PfamiPF00311. PEPcase. 1 hit.
    [Graphical view]
    PRINTSiPR00150. PEPCARBXLASE.
    SUPFAMiSSF51621. SSF51621. 1 hit.
    PROSITEiPS00781. PEPCASE_1. 1 hit.
    PS00393. PEPCASE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E4WH56-1 [UniParc]FASTAAdd to Basket

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    MMTGTSDSSA ASSVTSAPRA ATEPLRDDIR LLGGILGDIV REQAGEDVFD    50
    LVERARVESF RVRRSEIDRA ELAELFSTVD TADAIPVIRA FSHFALLANV 100
    AEDIHRERRR AIHVRAGEPP QDSTLAATYA KLDAAPVDPE IAAGALAGAL 150
    VAPVITAHPT ETRRRTVFET QNRIMELMRR REWVSVDPAE ADAVDRQLRR 200
    QILTLWQTAL IRLSRLRIQD EIEVGLRYYD ASLFEVVPRI NAELRDALRS 250
    RWPDSGVLTE PMLRPGSWIG GDRDGNPYVT ADVVARATHR ASETALEHHL 300
    AELEVLEREL SMSARLVTVT PELNRLADES GDESAFRADE PYRRAVRGLR 350
    ARLTGTAARI LGHPAAHAVA GELPDYRDPA ELLADLEIID TSLRSHGDGT 400
    VADDRLAQLR NSVEVFGFHL CGLDMRQNSE VHETVVAELL AWSGVHPDYA 450
    SLPEDERVAL LTRELATRRP LAGPHAEFSE LTTKELGILR AAADAVDRIG 500
    PEAIPNYVIS MCESVSDMLE AAILLAEVGL FDPDGEAGPR CPVGIVPLFE 550
    TIEDLRHGAE TLTATLDVPL YRALVANRGD SQEVMLGYSD SNKDGGYLAA 600
    NWALYRAELD LVRVAREKGI RLRLFHGRGG TVGRGGGPSY DAILAQPPGA 650
    VEGSLRITEQ GEIIAAKYAE PRLARRNLEA LVSATLESTL LDVEGLGDDA 700
    APAYAVLDEL AELARVAYAD LVHDTPGFVE YFEASTPVAE IGALNIGSRP 750
    ASRKQTQSIS DLRAIPWVLS WSQSRVMLPG WYGTGTAFEK WVGDDAGRLA 800
    TLTDLYERWP FFRTVLSNMA QVLSKSDMGL AARYSELVPD AELREEVFGK 850
    ISAEHARTLA MYRAVTGHDN LLWDNPALDR SVHNRFPYLE PLNHLQVELL 900
    RRYRAGDDSD NVRRGIQLTM NGLATALRNS G 931
    Length:931
    Mass (Da):102,310
    Last modified:February 8, 2011 - v1
    Checksum:i65E97218CAD1F0A1
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FN563149 Genomic DNA. Translation: CBH48261.1.
    RefSeqiYP_004006945.1. NC_014659.1.

    Genome annotation databases

    EnsemblBacteriaiCBH48261; CBH48261; REQ_22080.
    GeneIDi9964876.
    KEGGireq:REQ_22080.
    PATRICi42661839. VBIRhoEqu141084_2204.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FN563149 Genomic DNA. Translation: CBH48261.1 .
    RefSeqi YP_004006945.1. NC_014659.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CBH48261 ; CBH48261 ; REQ_22080 .
    GeneIDi 9964876.
    KEGGi req:REQ_22080.
    PATRICi 42661839. VBIRhoEqu141084_2204.

    Phylogenomic databases

    HOGENOMi HOG000238647.
    KOi K01595.
    OMAi GIQITIN.

    Enzyme and pathway databases

    BioCyci REQU685727:GHKP-2134-MONOMER.

    Family and domain databases

    HAMAPi MF_00595. PEPcase_type1.
    InterProi IPR021135. PEP_COase.
    IPR018129. PEP_COase_AS.
    IPR022805. PEP_COase_bac/pln-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view ]
    Pfami PF00311. PEPcase. 1 hit.
    [Graphical view ]
    PRINTSi PR00150. PEPCARBXLASE.
    SUPFAMi SSF51621. SSF51621. 1 hit.
    PROSITEi PS00781. PEPCASE_1. 1 hit.
    PS00393. PEPCASE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 103SImported.

    Entry informationi

    Entry nameiE4WH56_RHOE1
    AccessioniPrimary (citable) accession number: E4WH56
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 8, 2011
    Last sequence update: February 8, 2011
    Last modified: October 1, 2014
    This is version 22 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3