ID   E4U9U3_OCEP5            Unreviewed;       536 AA.
AC   E4U9U3;
DT   08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT   08-FEB-2011, sequence version 1.
DT   27-MAR-2024, entry version 59.
DE   RecName: Full=Glycerol-3-phosphate dehydrogenase {ECO:0000256|RuleBase:RU361217};
DE            EC=1.1.5.3 {ECO:0000256|RuleBase:RU361217};
GN   OrderedLocusNames=Ocepr_1805 {ECO:0000313|EMBL:ADR37257.1};
OS   Oceanithermus profundus (strain DSM 14977 / NBRC 100410 / VKM B-2274 /
OS   506).
OC   Bacteria; Deinococcota; Deinococci; Thermales; Thermaceae; Oceanithermus.
OX   NCBI_TaxID=670487 {ECO:0000313|EMBL:ADR37257.1, ECO:0000313|Proteomes:UP000008722};
RN   [1] {ECO:0000313|Proteomes:UP000008722}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 14977 / NBRC 100410 / VKM B-2274 / 506
RC   {ECO:0000313|Proteomes:UP000008722};
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Lucas S., Copeland A., Lapidus A., Bruce D., Goodwin L., Pitluck S.,
RA   Kyrpides N., Mavromatis K., Pagani I., Ivanova N., Zhang X., Brettin T.,
RA   Detter J.C., Tapia R., Han C., Land M., Hauser L., Markowitz V.,
RA   Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Tindall B., Faehnrich R.,
RA   Brambilla E., Klenk H.-P., Eisen J.A.;
RT   "The complete sequence of chromosome of Oceanithermus profundus DSM
RT   14977.";
RL   Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ADR37257.1, ECO:0000313|Proteomes:UP000008722}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 14977 / NBRC 100410 / VKM B-2274 / 506
RC   {ECO:0000313|Proteomes:UP000008722};
RX   PubMed=21677858; DOI=10.4056/sigs.1734292;
RA   Pati A., Zhang X., Lapidus A., Nolan M., Lucas S., Del Rio T.G., Tice H.,
RA   Cheng J.F., Tapia R., Han C., Goodwin L., Pitluck S., Liolios K.,
RA   Pagani I., Ivanova N., Mavromatis K., Chen A., Palaniappan K., Hauser L.,
RA   Jeffries C.D., Brambilla E.M., Rohl A., Mwirichia R., Rohde M.,
RA   Tindall B.J., Sikorski J., Wirth R., Goker M., Woyke T., Detter J.C.,
RA   Bristow J., Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C.,
RA   Klenk H.P., Land M.;
RT   "Complete genome sequence of Oceanithermus profundus type strain (506).";
RL   Stand. Genomic Sci. 4:210-220(2011).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a quinone + sn-glycerol 3-phosphate = a quinol +
CC         dihydroxyacetone phosphate; Xref=Rhea:RHEA:18977, ChEBI:CHEBI:24646,
CC         ChEBI:CHEBI:57597, ChEBI:CHEBI:57642, ChEBI:CHEBI:132124; EC=1.1.5.3;
CC         Evidence={ECO:0000256|RuleBase:RU361217};
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974,
CC         ECO:0000256|RuleBase:RU361217};
CC   -!- SIMILARITY: Belongs to the FAD-dependent glycerol-3-phosphate
CC       dehydrogenase family. {ECO:0000256|ARBA:ARBA00007330,
CC       ECO:0000256|RuleBase:RU361217}.
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DR   EMBL; CP002361; ADR37257.1; -; Genomic_DNA.
DR   RefSeq; WP_013458427.1; NC_014761.1.
DR   AlphaFoldDB; E4U9U3; -.
DR   STRING; 670487.Ocepr_1805; -.
DR   KEGG; opr:Ocepr_1805; -.
DR   eggNOG; COG0578; Bacteria.
DR   HOGENOM; CLU_015740_4_1_0; -.
DR   OrthoDB; 9766796at2; -.
DR   Proteomes; UP000008722; Chromosome.
DR   GO; GO:0009331; C:glycerol-3-phosphate dehydrogenase complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0004368; F:glycerol-3-phosphate dehydrogenase (quinone) activity; IEA:UniProtKB-EC.
DR   GO; GO:0006072; P:glycerol-3-phosphate metabolic process; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.8.870; Alpha-glycerophosphate oxidase, cap domain; 1.
DR   Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR031656; DAO_C.
DR   InterPro; IPR038299; DAO_C_sf.
DR   InterPro; IPR006076; FAD-dep_OxRdtase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR000447; G3P_DH_FAD-dep.
DR   PANTHER; PTHR11985; GLYCEROL-3-PHOSPHATE DEHYDROGENASE; 1.
DR   PANTHER; PTHR11985:SF15; GLYCEROL-3-PHOSPHATE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR   Pfam; PF01266; DAO; 1.
DR   Pfam; PF16901; DAO_C; 1.
DR   PRINTS; PR01001; FADG3PDH.
DR   SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   PROSITE; PS00977; FAD_G3PDH_1; 1.
DR   PROSITE; PS00978; FAD_G3PDH_2; 1.
PE   3: Inferred from homology;
KW   FAD {ECO:0000256|ARBA:ARBA00022827};
KW   Flavoprotein {ECO:0000256|ARBA:ARBA00022630,
KW   ECO:0000256|RuleBase:RU361217};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000256|RuleBase:RU361217};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008722}.
FT   DOMAIN          16..377
FT                   /note="FAD dependent oxidoreductase"
FT                   /evidence="ECO:0000259|Pfam:PF01266"
FT   DOMAIN          400..520
FT                   /note="Alpha-glycerophosphate oxidase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16901"
SQ   SEQUENCE   536 AA;  59380 MW;  5711EB7998357E9D CRC64;
     MNREKQLDAL KNRTFDLLVI GGGATGAGIA LDAATRGLSV ALVERGDFSE GTSSRSTKLV
     HGGVRYLEAA VKHLDRVQYN LVRDALRERG IILRLAPHLA HPIPLLTPLY RAWEVPYYFS
     GLKAYDLLAG HERLKPSRFV PRSRALEEFP QLKEEGLVGG VEYYDGQFDD ARMNVAVILT
     ALREGATVAN YVEVTGLVKQ GDRVAGAEVR DRLADEDFTV RARTVVNATG PFTDLIRRMD
     DPDAPPMVVT SSGVHIVLPG RFSPPGTGLL IPKTEDGRVL FVLPWMGHTL AGTTDEPAEL
     SFHPRPQEEE IDYILRHLKR YFALEPGRDD ILAAWSGLRP LVRDPKAHDT AELARDHIIS
     ESDSGLVTIA GGKWTTYRKM AEDLVDYVVR TRDLHPARGC ITDRVFVEGA AGFDADGWRG
     LVERFGLDED VARHLNQSYG DRAPEVARLA AEGFGERLAQ EHPFVEAEVV WAVRREMAVT
     PIDALARRTR LAFLDQKAAL AALKRTADLM AAELGWSVEE QQAHVDEART RLLEAL
//