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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Oceanithermus profundus (strain DSM 14977 / NBRC 100410 / VKM B-2274 / 506)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei134 – 1341UniRule annotation
Active sitei534 – 5341UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciOPRO670487:GH5I-843-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:Ocepr_0828Imported
OrganismiOceanithermus profundus (strain DSM 14977 / NBRC 100410 / VKM B-2274 / 506)Imported
Taxonomic identifieri670487 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeOceanithermus
ProteomesiUP000008722: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000238647.
KOiK01595.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E4U870-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLPEALRRD VDRLGRALGE AIREVSGERL YELVEEVRAR TKRLRQRPDD
60 70 80 90 100
AERAALVRLV ASLDLHRAEG LTRAFTSFFY LANLAESYHR VHTAADAKGE
110 120 130 140 150
FARAARTLAS WGVPPEEAAR LARSMRLWLT FTAHPTEARR RTVRHHLERL
160 170 180 190 200
RDALARGDRA AVRERVKLLW ATEELRRTQP TVEDEVKGAL YYLPESLWSA
210 220 230 240 250
QARLVERIEA ALEQAFGKRF EAESPVRTRS WIGGDRDGNP AVTPEVTAWA
260 270 280 290 300
QDHARRLYVE HFCRELDELV RDLSVSERRL PVPRELREAA ERALALIERA
310 320 330 340 350
PRFEGEPLRR YLMGVYYRLE HTLGSGPGAY GDAGELAGDL ERLRRTLEAM
360 370 380 390 400
GFSAFAARGV RPLEEAARTF GLSFADLDLR EEASEHREAV AELVAAAGLA
410 420 430 440 450
DDYPEWSDDR REAWLTGELA SARPLAPVGY RPRGKALRRA LGALEVWDGR
460 470 480 490 500
GAYVVSMTKS PADLLEVLLL AREAGRYRPD RGAPFDVVPL FETLADLDAA
510 520 530 540 550
GRTVERLLAN PVFRRQVEAR GALEVMIGYS DSNKDAGYLA ANWALYTAQQ
560 570 580 590 600
RIAEAARAAG VSVRFFHGRG TSTARGGGPA GRAIAALPVG TVGREIRITE
610 620 630 640 650
QGEALADKYA HPDLALRSLE ETIAHLWLAA ARDAGYGPEA AFAPEPAWVA
660 670 680 690 700
AIEAAAARSA QVYRELLGSE GFLAFFEQLT PIREIAALKI ASRPVYRHGR
710 720 730 740 750
IQEIRDLRAI PWVMAWTQVR ANLPGWYGLG EGLSAIDPAL LGEMHDGWPF
760 770 780 790 800
FRSVLEGAEL SLAKTDLEVT RGYLRLVDPE LAGRFFSAIE RAHEAALSTL
810 820 830 840 850
EKARGRPLLA DAPGLARSLE LRNPYLDPIN HLQIELLYRY RRLPPESPDR
860 870
ESTTRALLST ILGIAAGMRN TG
Length:872
Mass (Da):96,987
Last modified:February 8, 2011 - v1
Checksum:i33F046DB6FEB25AB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002361 Genomic DNA. Translation: ADR36285.1.
RefSeqiWP_013457455.1. NC_014761.1.
YP_004057458.1. NC_014761.1.

Genome annotation databases

EnsemblBacteriaiADR36285; ADR36285; Ocepr_0828.
GeneIDi10015677.
KEGGiopr:Ocepr_0828.
PATRICi45304993. VBIOcePro145519_0952.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002361 Genomic DNA. Translation: ADR36285.1.
RefSeqiWP_013457455.1. NC_014761.1.
YP_004057458.1. NC_014761.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADR36285; ADR36285; Ocepr_0828.
GeneIDi10015677.
KEGGiopr:Ocepr_0828.
PATRICi45304993. VBIOcePro145519_0952.

Phylogenomic databases

HOGENOMiHOG000238647.
KOiK01595.

Enzyme and pathway databases

BioCyciOPRO670487:GH5I-843-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 14977 / NBRC 100410 / VKM B-2274 / 506Imported.

Entry informationi

Entry nameiE4U870_OCEP5
AccessioniPrimary (citable) accession number: E4U870
Entry historyi
Integrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: March 4, 2015
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.