ID   E4TS21_MARTH            Unreviewed;       533 AA.
AC   E4TS21;
DT   08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT   08-FEB-2011, sequence version 1.
DT   27-MAR-2024, entry version 58.
DE   RecName: Full=DNA ligase (ATP) {ECO:0000256|ARBA:ARBA00012727};
DE            EC=6.5.1.1 {ECO:0000256|ARBA:ARBA00012727};
GN   OrderedLocusNames=Ftrac_0770 {ECO:0000313|EMBL:ADR20772.1};
OS   Marivirga tractuosa (strain ATCC 23168 / DSM 4126 / NBRC 15989 / NCIMB 1408
OS   / VKM B-1430 / H-43) (Microscilla tractuosa) (Flexibacter tractuosus).
OC   Bacteria; Bacteroidota; Cytophagia; Cytophagales; Marivirgaceae; Marivirga.
OX   NCBI_TaxID=643867 {ECO:0000313|EMBL:ADR20772.1, ECO:0000313|Proteomes:UP000008720};
RN   [1] {ECO:0000313|EMBL:ADR20772.1, ECO:0000313|Proteomes:UP000008720}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 23168 / DSM 4126 / NBRC 15989 / NCIMB 1408 / VKM B-1430 /
RC   H-43 {ECO:0000313|Proteomes:UP000008720};
RX   PubMed=21677852; DOI=10.4056/sigs.1623941;
RA   Pagani I., Chertkov O., Lapidus A., Lucas S., Del Rio T.G., Tice H.,
RA   Copeland A., Cheng J.F., Nolan M., Saunders E., Pitluck S., Held B.,
RA   Goodwin L., Liolios K., Ovchinikova G., Ivanova N., Mavromatis K., Pati A.,
RA   Chen A., Palaniappan K., Land M., Hauser L., Jeffries C.D., Detter J.C.,
RA   Han C., Tapia R., Ngatchou-Djao O.D., Rohde M., Goker M., Spring S.,
RA   Sikorski J., Woyke T., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P.,
RA   Klenk H.P., Kyrpides N.C.;
RT   "Complete genome sequence of Marivirga tractuosa type strain (H-43).";
RL   Stand. Genomic Sci. 4:154-162(2011).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-
CC         (deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP +
CC         diphosphate.; EC=6.5.1.1; Evidence={ECO:0000256|ARBA:ARBA00034003};
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DR   EMBL; CP002349; ADR20772.1; -; Genomic_DNA.
DR   RefSeq; WP_013452923.1; NC_014759.1.
DR   AlphaFoldDB; E4TS21; -.
DR   STRING; 643867.Ftrac_0770; -.
DR   KEGG; mtt:Ftrac_0770; -.
DR   eggNOG; COG1793; Bacteria.
DR   HOGENOM; CLU_005138_6_2_10; -.
DR   OrthoDB; 9767858at2; -.
DR   Proteomes; UP000008720; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003910; F:DNA ligase (ATP) activity; IEA:UniProtKB-EC.
DR   GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   CDD; cd07897; Adenylation_DNA_ligase_Bac1; 1.
DR   CDD; cd07972; OBF_DNA_ligase_Arch_LigB; 1.
DR   Gene3D; 1.10.3260.10; DNA ligase, ATP-dependent, N-terminal domain; 1.
DR   Gene3D; 3.30.470.30; DNA ligase/mRNA capping enzyme; 1.
DR   Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR   InterPro; IPR026333; ATP_dep_DNA_lig_pp_1105_fam.
DR   InterPro; IPR012309; DNA_ligase_ATP-dep_C.
DR   InterPro; IPR012310; DNA_ligase_ATP-dep_cent.
DR   InterPro; IPR016059; DNA_ligase_ATP-dep_CS.
DR   InterPro; IPR012308; DNA_ligase_ATP-dep_N.
DR   InterPro; IPR036599; DNA_ligase_N_sf.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   NCBIfam; TIGR04120; DNA_lig_bact; 1.
DR   PANTHER; PTHR45674; DNA LIGASE 1/3 FAMILY MEMBER; 1.
DR   PANTHER; PTHR45674:SF13; DNA LIGASE-RELATED; 1.
DR   Pfam; PF04679; DNA_ligase_A_C; 1.
DR   Pfam; PF01068; DNA_ligase_A_M; 1.
DR   Pfam; PF04675; DNA_ligase_A_N; 1.
DR   SUPFAM; SSF117018; ATP-dependent DNA ligase DNA-binding domain; 1.
DR   SUPFAM; SSF56091; DNA ligase/mRNA capping enzyme, catalytic domain; 1.
DR   SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR   PROSITE; PS00697; DNA_LIGASE_A1; 1.
DR   PROSITE; PS50160; DNA_LIGASE_A3; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:ADR20772.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008720}.
FT   DOMAIN          307..437
FT                   /note="ATP-dependent DNA ligase family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50160"
SQ   SEQUENCE   533 AA;  61868 MW;  165EDE93AE18BEB8 CRC64;
     MKEFAQLITS LDQSNKTNDK VNALKNYFLS ANDQDKIWTL ALFTHRKPKR TVNTNLLKDW
     VTEWTGIPEW LFQESYQVVG DLAETISLLV ASTDEGYKEV DNLLSYYIKT LISLRDKSIE
     EKKKRLQSIY KELDPQERFV FTKIMTGGWR VGVSQNLITK ALSEAFDIDK SIIAHRLMGN
     WSPENFTFQE LILEESKNDL ASRPYPFYLA HPIETQEIQE ELNPAEWQAE WKWDGIRGQI
     IKRNDEVFIW SRGEELVTEK FPELVEMAEK LPNGAVLDGE ITAYRNGEPL SFGVLQTRIG
     RKNITKNLIK KAPVVFICYD IIEHKGKDIR TKALSYRTQL LNQLLLEIDH PILLASQSIE
     FSDWVELIEI RKKSRSLKTE GLMLKKKNSI YEAGRKRGSW WKWKIAPLTI DGVMIYAQKG
     HGRRADLYSD YTLAVWNEDE LIPFAKAYSG LTDAEMKKVD AFVKKNTKEK FGPVRTVKPE
     LVFEIAFEGI QVSNRHKSGI ALRFPRIKRW RQDKPISEAN KLTDLQHLLE KYG
//