E4THX8 (E4THX8_CALNY) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Enoyl-[acyl-carrier-protein] reductase [NADH] PIRNR PIRNR000094
EC=1.3.1.9 PIRNR PIRNR000094

Gene names

Ordered Locus Names:

Calni_0997 EMBL ADR18908.1

Organism

Calditerrivibrio nitroreducens (strain DSM 19672 / NBRC 101217 / Yu37-1) [Complete proteome] [HAMAP] EMBL ADR18908.1

Taxonomic identifier

768670 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Deferribacteres › Deferribacteres › Deferribacterales › Deferribacteraceae › Calditerrivibrio › Calditerrivibrio nitroreducens

Protein attributes

Sequence length	255 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Acyl-[acyl-carrier-protein] + NAD+ = trans-2,3-dehydroacyl-[acyl-carrier-protein] + NADH. PIRNR PIRNR000094
Pathway	Lipid metabolism; fatty acid biosynthesis. PIRNR PIRNR000094
Sequence similarities	Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. PIRNR PIRNR000094

Ontologies

Keywords
Biological process	Fatty acid biosynthesis PIRNR PIRNR000094 Fatty acid metabolism Lipid biosynthesis Lipid metabolism
Ligand	NAD PIRNR PIRNR000094
Molecular function	Oxidoreductase PIRNR PIRNR000094 EMBL ADR18908.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	fatty acid biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	enoyl-[acyl-carrier-protein] reductase (NADH) activity Inferred from electronic annotation. Source: EC nucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	145	1	Proton acceptor By similarity PIRSR PIRSR000094-1
	Active site	155	1	Proton acceptor By similarity PIRSR PIRSR000094-1
	Binding site	95	1	Substrate; via amide nitrogen and carbonyl oxygen By similarity PIRSR PIRSR000094-2

Sequences

	Sequence		Length	Mass (Da)
	E4THX8 [UniParc]. Last modified February 8, 2011. Version 1. Checksum: 0D3EDD87A88F41CA	FASTA	255	27,177
	10 20 30 40 50 60 MRLLEGKNAV IFGVANDKSI AYAISKLFKE NGANLGFTYA GEALKKRVEP ISEELGGKFC 70 80 90 100 110 120 IQCDVSKDED ILSSAQKAKE LFGKVDIIVH SVAYAPAEAL KGRFVDTPRE GFKIALDISA 130 140 150 160 170 180 YSLVAICKAY EEILSDNASI VTMTYYGSVK VVQNYNVMGV AKAALESSVR YLANDLGPKG 190 200 210 220 230 240 VRVNAISAGP IKTLAASGIS GFKSILSQIE EKAPLKKNVT QEDVAKAALF LCSDLGSGVT 250 GDILYVDSGY NILGL

References

[1]

"The complete genome of chromosome of Calditerrivibrio nitroreducens DSM 19672." US DOE Joint Genome Institute (JGI-PGF) Lucas S., Copeland A., Lapidus A., Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N., Mikhailova N., Zeytun A., Brettin T., Detter J.C., Tapia R., Han C., Land M., Hauser L., Markowitz V. , Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Spring S., Schroeder M., Brambilla E., Klenk H.-P., Eisen J.A. Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 19672.

[2]

"Complete genome sequence of Calditerrivibrio nitroreducens type strain (Yu37-1)." Pitluck S., Sikorski J., Zeytun A., Lapidus A., Nolan M., Lucas S., Hammon N., Deshpande S., Cheng J.F., Tapia R., Han C., Goodwin L., Liolios K., Pagani I., Ivanova N., Mavromatis K., Pati A., Chen A. , Palaniappan K., Hauser L., Chang Y.J., Jeffries C.D., Detter J.C., Brambilla E., Djao O.D., Rohde M., Spring S., Goker M., Woyke T., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P., Land M. Stand. Genomic Sci. 4:54-62(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 19672 / NBRC 101217 / Yu37-1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002347 Genomic DNA. Translation: ADR18908.1.
RefSeq	YP_004051071.1. NC_014758.1.
3D structure databases
ProteinModelPortal	E4THX8.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADR18908; ADR18908; Calni_0997.
GeneID	10009013.
KEGG	cni:Calni_0997.
PATRIC	45189726. VBICalNit163602_1073.
Organism-specific databases
CMR	Search...
Phylogenomic databases
KO	K00208.
OMA	DCDVGSD.
Enzyme and pathway databases
BioCyc	CNIT768670:GHD1-1015-MONOMER.
UniPathway	UPA00094.
Family and domain databases
Gene3D	3.40.50.720. 1 hit.
InterPro	IPR014358. Enoyl-ACP_Rdtase_NADH. IPR002347. Glc/ribitol_DH. IPR016040. NAD(P)-bd_dom. [Graphical view]
PIRSF	PIRSF000094. Enoyl-ACP_rdct. 1 hit.
PRINTS	PR00081. GDHRDH.
ProtoNet	Search...

Entry information

Entry name

E4THX8_CALNY

Accession

Primary (citable) accession number: E4THX8

Entry history

Integrated into UniProtKB/TrEMBL:	February 8, 2011
Last sequence update:	February 8, 2011
Last modified:	May 1, 2013
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)