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E4TFX7 (E4TFX7_CALNY) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
UDP-N-acetylmuramoylalanine--D-glutamate ligase RuleBase RU003664 HAMAP-Rule MF_00639

EC=6.3.2.9 RuleBase RU003664 HAMAP-Rule MF_00639
Alternative name(s):
D-glutamic acid-adding enzyme HAMAP-Rule MF_00639
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase HAMAP-Rule MF_00639
Gene names
Name:murD HAMAP-Rule MF_00639
Ordered Locus Names:Calni_1727 EMBL ADR19633.1
OrganismCalditerrivibrio nitroreducens (strain DSM 19672 / NBRC 101217 / Yu37-1) [Complete proteome] [HAMAP] EMBL ADR19633.1
Taxonomic identifier768670 [NCBI]
Taxonomic lineageBacteriaDeferribacteresDeferribacteralesDeferribacteraceae

Protein attributes

Sequence length416 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) By similarity. HAMAP-Rule MF_00639 SAAS SAAS005762

Catalytic activity

ATP + UDP-N-acetylmuramoyl-L-alanine + glutamate = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate. HAMAP-Rule MF_00639 SAAS SAAS005762

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00639 SAAS SAAS005762

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00639 SAAS SAAS005762.

Sequence similarities

Belongs to the MurCDEF family. HAMAP-Rule MF_00639 RuleBase RU003630

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding90 – 967ATP By similarity HAMAP-Rule MF_00639

Sequences

Sequence LengthMass (Da)Tools
E4TFX7 [UniParc].

Last modified February 8, 2011. Version 1.
Checksum: 1DA6835077503310

FASTA41646,826
        10         20         30         40         50         60 
MKAAILGYGK SGQTAKRLLE IKGTETIEIY DDKMDGFKGI KDFNYEEFDT VVVSPGIDLT 

        70         80         90        100        110        120 
NIDLPTERIT SELELAFEFI KDKKIIGITG TNGKSTVTFL TAQLLKNIGI NAEFCGNIGV 

       130        140        150        160        170        180 
TVGDTYLLKN PDVYVVEVSS FQLDLLKRFR FDTSTITNIT PDHLDRYKTM DRYITSKSRM 

       190        200        210        220        230        240 
VEFTEGVSFL EKGGWNEIFK KYENIKYVDG ELKSYPLLNG NLLEFEDFYV DVNRYNLFGF 

       250        260        270        280        290        300 
HNIVNLSFAL LLTNQIVRLK GDVTGLVENL TPLEHRCELV TEINGVKYIN DSKGTNVDST 

       310        320        330        340        350        360 
LTALKSSSYP TTLILGGKDK NGDFSVLSDE INKKAKLVIC CGAAGEKIYN SLKDIIDVKI 

       370        380        390        400        410 
VRVELLKDAI SLAYRETKEG TVLFSPACAS FDEFNNFEER GRFFKNYVNN LKVRGC 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002347 Genomic DNA. Translation: ADR19633.1.
RefSeqYP_004051796.1. NC_014758.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADR19633; ADR19633; Calni_1727.
GeneID10009764.
KEGGcni:Calni_1727.
PATRIC45191256. VBICalNit163602_1817.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000049428.
KOK01925.
OMAPEYWAVE.

Enzyme and pathway databases

BioCycCNIT768670:GHD1-1766-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.40.1190.10. 1 hit.
3.90.190.20. 1 hit.
HAMAPMF_00639. MurD.
InterProIPR018109. Folylpolyglutamate_synth_CS.
IPR004101. Mur_ligase_C.
IPR013221. Mur_ligase_cen.
IPR005762. UDP-N-AcMur-Glu_ligase.
[Graphical view]
PfamPF02875. Mur_ligase_C. 1 hit.
PF08245. Mur_ligase_M. 1 hit.
[Graphical view]
SUPFAMSSF53244. SSF53244. 1 hit.
SSF53623. SSF53623. 1 hit.
TIGRFAMsTIGR01087. murD. 1 hit.
PROSITEPS01011. FOLYLPOLYGLU_SYNT_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameE4TFX7_CALNY
AccessionPrimary (citable) accession number: E4TFX7
Entry history
Integrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: June 11, 2014
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)