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E4TD77 (E4TD77_RIEAD) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
D-alanine--D-alanine ligase HAMAP-Rule MF_00047

EC=6.3.2.4 HAMAP-Rule MF_00047
Alternative name(s):
D-Ala-D-Ala ligase HAMAP-Rule MF_00047
D-alanylalanine synthetase HAMAP-Rule MF_00047
Gene names
Name:ddl HAMAP-Rule MF_00047
Ordered Locus Names:Riean_1579 EMBL ADQ82736.1
ORF Names:RA0C_1871 EMBL AFD56746.1
OrganismRiemerella anatipestifer (strain ATCC 11845 / DSM 15868 / JCM 9532 / NCTC 11014) [Complete proteome] [HAMAP] EMBL ADQ82736.1
Taxonomic identifier693978 [NCBI]
Taxonomic lineageBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceaeRiemerella

Protein attributes

Sequence length327 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. SAAS SAAS011127 HAMAP-Rule MF_00047

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. SAAS SAAS011127 HAMAP-Rule MF_00047

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. SAAS SAAS011127 HAMAP-Rule MF_00047

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. SAAS SAAS011127 HAMAP-Rule MF_00047

Subcellular location

Cytoplasm By similarity SAAS SAAS011127 HAMAP-Rule MF_00047.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00047

Contains ATP-grasp domain. SAAS SAAS011127

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain123 – 322200ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding151 – 20656ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding2771Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2891Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2891Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding2911Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
E4TD77 [UniParc].

Last modified February 8, 2011. Version 1.
Checksum: CC0D89F980A0ACE6

FASTA32736,504
        10         20         30         40         50         60 
MSKKNIAVVM GGYSDEYKVS LKSGQLIYDS LDRDLYNVYK VVVLKEGWFY LDENEAKLPI 

        70         80         90        100        110        120 
QKGDFSVNLP SGEVLRFDVC FNTIHGTPGE NGVLQAYWDA IGQKYTGCDF YQSALTFNKK 

       130        140        150        160        170        180 
DTLAVLAKYG IPSAKSFYIK KGEAYDKDKI INELKLPLFV KPNQSGSSLG ISKVKEVSEF 

       190        200        210        220        230        240 
EAALEKAFLE DDEVLVESFL DGMEVSVGVL DYKGETIVLG ITEIIPETEF FDYEAKYQGA 

       250        260        270        280        290        300 
SQEITPARLD EATRLRVEEV AKRAYNSLGM KGFSRSEYII MNGVPYMLEM NTNPGFSPAS 

       310        320 
ILPQQARIYG ISIKDLCGNE VEKALAK 

« Hide

References

« Hide 'large scale' references
[1]"Complete genome sequence of Riemerella anatipestifer type strain (ATCC 11845)."
Mavromatis K., Lu M., Misra M., Lapidus A., Nolan M., Lucas S., Hammon N., Deshpande S., Cheng J.F., Tapia R., Han C., Goodwin L., Pitluck S., Liolios K., Pagani I., Ivanova N., Mikhailova N., Pati A. expand/collapse author list , Chen A., Palaniappan K., Land M., Hauser L., Jeffries C.D., Detter J.C., Brambilla E.M., Rohde M., Goker M., Gronow S., Woyke T., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P., Klenk H.P., Kyrpides N.C.
Stand. Genomic Sci. 4:144-153(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 11845 / DSM 15868 / JCM 9532 / NCTC 11014 and DSM 15868 EMBL ADQ82736.1.
[2]"Complete genome sequence of Riemerella anatipestifer reference strain."
Wang X., Zhu D., Wang M., Cheng A., Jia R., Zhou Y., Chen Z., Luo Q., Liu F., Wang Y., Chen X.Y.
J. Bacteriol. 194:3270-3271(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 11845 EMBL AFD56746.1.
[3]"Riemerella anatipestifer ATCC 11845 Complete Genome."
Cheng A.-C., Wang M.-S., Zhu D.-K., Wang X.-J.
Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: ATCC 11845 EMBL AFD56746.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002346 Genomic DNA. Translation: ADQ82736.1.
CP003388 Genomic DNA. Translation: AFD56746.1.
RefSeqYP_004046242.1. NC_014738.1.
YP_005395289.1. NC_017045.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADQ82736; ADQ82736; Riean_1579.
AFD56746; AFD56746; RA0C_1871.
GeneID10002357.
11997644.
KEGGrai:RA0C_1871.
ran:Riean_1579.
PATRIC45353953. VBIRieAna155424_1607.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000011592.
KOK01921.

Enzyme and pathway databases

BioCycRANA693978:GHF6-1627-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 2 hits.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 1 hit.
[Graphical view]
SUPFAMSSF52440. SSF52440. 1 hit.
TIGRFAMsTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameE4TD77_RIEAD
AccessionPrimary (citable) accession number: E4TD77
Entry history
Integrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: February 19, 2014
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)