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E4T8V8 (E4T8V8_RIEAD) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 30. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names
EC=1.1.1.42 EMBL ADQ81372.1

Isocitrate dehydrogenase, nADP-dependent EMBL AFD55390.1
Gene names
Ordered Locus Names:Riean_0199 EMBL ADQ81372.1
ORF Names:RA0C_0407 EMBL AFD55390.1
OrganismRiemerella anatipestifer (strain ATCC 11845 / DSM 15868 / JCM 9532 / NCTC 11014) [Complete proteome] [HAMAP] EMBL ADQ81372.1
Taxonomic identifier693978 [NCBI]
Taxonomic lineageBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceaeRiemerella

Protein attributes

Sequence length738 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existencePredicted

General annotation (Comments)

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. PIRSR PIRSR009407-3

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 3030 Potential EMBL ADQ81372.1
Chain31 – 738708 Potential EMBL ADQ81372.1
PRO_5000661345

Regions

Region132 – 1398Substrate binding By similarity PIRSR PIRSR009407-2

Sites

Metal binding3481Magnesium or manganese By similarity PIRSR PIRSR009407-3
Metal binding5461Magnesium or manganese By similarity PIRSR PIRSR009407-3
Metal binding5501Magnesium or manganese By similarity PIRSR PIRSR009407-3
Binding site1451Substrate By similarity PIRSR PIRSR009407-2
Binding site5451Substrate By similarity PIRSR PIRSR009407-2
Site2551Critical for catalysis By similarity PIRSR PIRSR009407-1
Site4181Critical for catalysis By similarity PIRSR PIRSR009407-1

Sequences

Sequence LengthMass (Da)Tools
E4T8V8 [UniParc].

Last modified February 8, 2011. Version 1.
Checksum: B56B3E43408AFD12

FASTA73881,657
        10         20         30         40         50         60 
MSTAKIYYTL TDEAPMLATH SFLPIVKAFA KSADIQIEVP DISLSGRILA NFPEVLTEEQ 

        70         80         90        100        110        120 
RIPDALSQLG ELATKPEANI IKLPNISASI PQLNEAIEEL QKKGFNVPNY PAEPKTEEEK 

       130        140        150        160        170        180 
EIKAKYAKVL GSAVNPVLRE GNSDRRAPKA VKNYAKANPH RMGEWKSDSK TDVAHMNQGD 

       190        200        210        220        230        240 
FYGTETSTTV EKDGKFKIVF FGNDGSEKVL KDYASLQAGE IIDSSVMNIK ALKTFVKEAI 

       250        260        270        280        290        300 
QEAKSRNVLL SAHLKATMMK VSDPIIFGAI VETFFQEVFE KYAETFKSLD VNPNDGLASL 

       310        320        330        340        350        360 
YDKIAGIAQE ADIKVDIEHV LNESSRVAMV NSDKGITNFH VPSDVIVDAS MAALVRGGGK 

       370        380        390        400        410        420 
MWNKDGQEED TLAIIPDRSY AGFYQAVIDD MKANGKLDPT TMGSVPNVGL MAKKAEEYGS 

       430        440        450        460        470        480 
HDKTFQMEAE GTVKVLNENN EVLLEQKVET GDIFRMCQTK DAPIQDWVKL AVNRSRLSDT 

       490        500        510        520        530        540 
PAIFWLDKGR AHDREVIKKV EQYLKNYDTQ GLDIKILDVK DAMSETLKRA REGKDTISVS 

       550        560        570        580        590        600 
GNVLRDYLTD LFPILELGTS AKMLSIVPLM NGGGLFETGA GGSAPKHIEQ FIEEGYLRWD 

       610        620        630        640        650        660 
SLGEFLALQA SLEHLAQTQN NTKAQVLADA LDEANAKFLA NDKSPARKIG SIDNRGSHFY 

       670        680        690        700        710        720 
LALYWAEALA AQTQDSELST LFQPIAKEMQ ENEAKINEEL IASQGKAQDI EGYYRPNEDK 

       730 
TYAAMRPSVT LNQIIDRI 

« Hide

References

« Hide 'large scale' references
[1]"Complete genome sequence of Riemerella anatipestifer type strain (ATCC 11845)."
Mavromatis K., Lu M., Misra M., Lapidus A., Nolan M., Lucas S., Hammon N., Deshpande S., Cheng J.F., Tapia R., Han C., Goodwin L., Pitluck S., Liolios K., Pagani I., Ivanova N., Mikhailova N., Pati A. expand/collapse author list , Chen A., Palaniappan K., Land M., Hauser L., Jeffries C.D., Detter J.C., Brambilla E.M., Rohde M., Goker M., Gronow S., Woyke T., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P., Klenk H.P., Kyrpides N.C.
Stand. Genomic Sci. 4:144-153(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 11845 / DSM 15868 / JCM 9532 / NCTC 11014 and DSM 15868 EMBL ADQ81372.1.
[2]"Complete Genome Sequence of Riemerella anatipestifer Reference Strain."
Wang X., Zhu D., Wang M., Cheng A., Jia R., Zhou Y., Chen Z., Luo Q., Liu F., Wang Y., Chen X.Y.
J. Bacteriol. 194:3270-3271(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 11845 EMBL AFD55390.1.
[3]"Riemerella anatipestifer ATCC 11845 Complete Genome."
Cheng A.-C., Wang M.-S., Zhu D.-K., Wang X.-J.
Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: ATCC 11845 EMBL AFD55390.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002346 Genomic DNA. Translation: ADQ81372.1.
CP003388 Genomic DNA. Translation: AFD55390.1.
RefSeqYP_004044878.1. NC_014738.1.
YP_005393933.1. NC_017045.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADQ81372; ADQ81372; Riean_0199.
AFD55390; AFD55390; RA0C_0407.
GeneID10000930.
11996829.
KEGGrai:RA0C_0407.
ran:Riean_0199.
PATRIC45351038. VBIRieAna155424_0201.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000240860.
KOK00031.

Enzyme and pathway databases

BioCycRANA693978:GHF6-200-MONOMER.

Family and domain databases

Gene3D3.40.718.10. 3 hits.
InterProIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamPF03971. IDH. 1 hit.
[Graphical view]
PIRSFPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsTIGR00178. monomer_idh. 1 hit.
ProtoNetSearch...

Entry information

Entry nameE4T8V8_RIEAD
AccessionPrimary (citable) accession number: E4T8V8
Entry history
Integrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: July 9, 2014
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)