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E4T8V8

- E4T8V8_RIEAD

UniProt

E4T8V8 - E4T8V8_RIEAD

Protein
Submitted name:

Isocitrate dehydrogenase, NADP-dependent

Gene

Riean_0199

Organism
Riemerella anatipestifer (strain ATCC 11845 / DSM 15868 / JCM 9532 / NCTC 11014)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 32 (01 Oct 2014)
      Sequence version 1 (08 Feb 2011)
      Previous versions | rss
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    Functioni

    Cofactori

    Binds 1 magnesium or manganese ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei145 – 1451SubstrateUniRule annotation
    Sitei255 – 2551Critical for catalysisUniRule annotation
    Metal bindingi348 – 3481Magnesium or manganese
    Sitei418 – 4181Critical for catalysisUniRule annotation
    Binding sitei545 – 5451SubstrateUniRule annotation
    Metal bindingi546 – 5461Magnesium or manganese
    Metal bindingi550 – 5501Magnesium or manganese

    GO - Molecular functioni

    1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    OxidoreductaseImported

    Keywords - Ligandi

    MagnesiumUniRule annotation, Metal-bindingUniRule annotation

    Enzyme and pathway databases

    BioCyciRANA693978:GHF6-200-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Isocitrate dehydrogenase, NADP-dependentImported (EC:1.1.1.42Imported)
    Submitted name:
    Isocitrate dehydrogenase, nADP-dependentImported
    Gene namesi
    Ordered Locus Names:Riean_0199Imported
    ORF Names:RA0C_0407Imported
    OrganismiRiemerella anatipestifer (strain ATCC 11845 / DSM 15868 / JCM 9532 / NCTC 11014)Imported
    Taxonomic identifieri693978 [NCBI]
    Taxonomic lineageiBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceaeRiemerella
    ProteomesiUP000008719: Chromosome, UP000010093: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 3030 PotentialImportedAdd
    BLAST
    Chaini31 – 738708 PotentialImportedPRO_5000661345Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliE4T8V8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni132 – 1398Substrate bindingUniRule annotation

    Keywords - Domaini

    SignalImported

    Phylogenomic databases

    HOGENOMiHOG000240860.
    KOiK00031.

    Family and domain databases

    Gene3Di3.40.718.10. 3 hits.
    InterProiIPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view]
    PfamiPF03971. IDH. 1 hit.
    [Graphical view]
    PIRSFiPIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    E4T8V8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSTAKIYYTL TDEAPMLATH SFLPIVKAFA KSADIQIEVP DISLSGRILA    50
    NFPEVLTEEQ RIPDALSQLG ELATKPEANI IKLPNISASI PQLNEAIEEL 100
    QKKGFNVPNY PAEPKTEEEK EIKAKYAKVL GSAVNPVLRE GNSDRRAPKA 150
    VKNYAKANPH RMGEWKSDSK TDVAHMNQGD FYGTETSTTV EKDGKFKIVF 200
    FGNDGSEKVL KDYASLQAGE IIDSSVMNIK ALKTFVKEAI QEAKSRNVLL 250
    SAHLKATMMK VSDPIIFGAI VETFFQEVFE KYAETFKSLD VNPNDGLASL 300
    YDKIAGIAQE ADIKVDIEHV LNESSRVAMV NSDKGITNFH VPSDVIVDAS 350
    MAALVRGGGK MWNKDGQEED TLAIIPDRSY AGFYQAVIDD MKANGKLDPT 400
    TMGSVPNVGL MAKKAEEYGS HDKTFQMEAE GTVKVLNENN EVLLEQKVET 450
    GDIFRMCQTK DAPIQDWVKL AVNRSRLSDT PAIFWLDKGR AHDREVIKKV 500
    EQYLKNYDTQ GLDIKILDVK DAMSETLKRA REGKDTISVS GNVLRDYLTD 550
    LFPILELGTS AKMLSIVPLM NGGGLFETGA GGSAPKHIEQ FIEEGYLRWD 600
    SLGEFLALQA SLEHLAQTQN NTKAQVLADA LDEANAKFLA NDKSPARKIG 650
    SIDNRGSHFY LALYWAEALA AQTQDSELST LFQPIAKEMQ ENEAKINEEL 700
    IASQGKAQDI EGYYRPNEDK TYAAMRPSVT LNQIIDRI 738
    Length:738
    Mass (Da):81,657
    Last modified:February 8, 2011 - v1
    Checksum:iB56B3E43408AFD12
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002346 Genomic DNA. Translation: ADQ81372.1.
    CP003388 Genomic DNA. Translation: AFD55390.1.
    RefSeqiYP_004044878.1. NC_014738.1.
    YP_005393933.1. NC_017045.1.

    Genome annotation databases

    EnsemblBacteriaiADQ81372; ADQ81372; Riean_0199.
    AFD55390; AFD55390; RA0C_0407.
    GeneIDi10000930.
    11996829.
    KEGGirai:RA0C_0407.
    ran:Riean_0199.
    PATRICi45351038. VBIRieAna155424_0201.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002346 Genomic DNA. Translation: ADQ81372.1 .
    CP003388 Genomic DNA. Translation: AFD55390.1 .
    RefSeqi YP_004044878.1. NC_014738.1.
    YP_005393933.1. NC_017045.1.

    3D structure databases

    ProteinModelPortali E4T8V8.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADQ81372 ; ADQ81372 ; Riean_0199 .
    AFD55390 ; AFD55390 ; RA0C_0407 .
    GeneIDi 10000930.
    11996829.
    KEGGi rai:RA0C_0407.
    ran:Riean_0199.
    PATRICi 45351038. VBIRieAna155424_0201.

    Phylogenomic databases

    HOGENOMi HOG000240860.
    KOi K00031.

    Enzyme and pathway databases

    BioCyci RANA693978:GHF6-200-MONOMER.

    Family and domain databases

    Gene3Di 3.40.718.10. 3 hits.
    InterProi IPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view ]
    Pfami PF03971. IDH. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 11845 / DSM 15868 / JCM 9532 / NCTC 11014Imported and DSM 15868Imported.
    2. "Complete genome sequence of Riemerella anatipestifer reference strain."
      Wang X., Zhu D., Wang M., Cheng A., Jia R., Zhou Y., Chen Z., Luo Q., Liu F., Wang Y., Chen X.Y.
      J. Bacteriol. 194:3270-3271(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 11845Imported.
    3. "Riemerella anatipestifer ATCC 11845 Complete Genome."
      Cheng A.-C., Wang M.-S., Zhu D.-K., Wang X.-J.
      Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: ATCC 11845Imported.

    Entry informationi

    Entry nameiE4T8V8_RIEAD
    AccessioniPrimary (citable) accession number: E4T8V8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 8, 2011
    Last sequence update: February 8, 2011
    Last modified: October 1, 2014
    This is version 32 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3