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E4T8V8

- E4T8V8_RIEAD

UniProt

E4T8V8 - E4T8V8_RIEAD

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Protein
Submitted name:

Isocitrate dehydrogenase, NADP-dependent

Gene
Riean_0199, RA0C_0407
Organism
Riemerella anatipestifer (strain ATCC 11845 / DSM 15868 / JCM 9532 / NCTC 11014)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein predictedi

Functioni

Cofactori

Binds 1 magnesium or manganese ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei145 – 1451Substrate By similarity
Sitei255 – 2551Critical for catalysis By similarityUniRule annotation
Metal bindingi348 – 3481Magnesium or manganese By similarityUniRule annotation
Sitei418 – 4181Critical for catalysis By similarityUniRule annotation
Binding sitei545 – 5451Substrate By similarity
Metal bindingi546 – 5461Magnesium or manganese By similarityUniRule annotation
Metal bindingi550 – 5501Magnesium or manganese By similarityUniRule annotation

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciRANA693978:GHF6-200-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Isocitrate dehydrogenase, NADP-dependentImported (EC:1.1.1.42Imported)
Submitted name:
Isocitrate dehydrogenase, nADP-dependentImported
Gene namesi
Ordered Locus Names:Riean_0199Imported
ORF Names:RA0C_0407Imported
OrganismiRiemerella anatipestifer (strain ATCC 11845 / DSM 15868 / JCM 9532 / NCTC 11014)Imported
Taxonomic identifieri693978 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceaeRiemerella
ProteomesiUP000010093: Chromosome, UP000008719: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 3030 PredictedImportedAdd
BLAST
Chaini31 – 738708 PredictedImportedPRO_5000661345Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliE4T8V8.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni132 – 1398Substrate binding By similarityUniRule annotation

Keywords - Domaini

SignalImported

Phylogenomic databases

HOGENOMiHOG000240860.
KOiK00031.

Family and domain databases

Gene3Di3.40.718.10. 3 hits.
InterProiIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamiPF03971. IDH. 1 hit.
[Graphical view]
PIRSFiPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

E4T8V8-1 [UniParc]FASTAAdd to Basket

« Hide

MSTAKIYYTL TDEAPMLATH SFLPIVKAFA KSADIQIEVP DISLSGRILA    50
NFPEVLTEEQ RIPDALSQLG ELATKPEANI IKLPNISASI PQLNEAIEEL 100
QKKGFNVPNY PAEPKTEEEK EIKAKYAKVL GSAVNPVLRE GNSDRRAPKA 150
VKNYAKANPH RMGEWKSDSK TDVAHMNQGD FYGTETSTTV EKDGKFKIVF 200
FGNDGSEKVL KDYASLQAGE IIDSSVMNIK ALKTFVKEAI QEAKSRNVLL 250
SAHLKATMMK VSDPIIFGAI VETFFQEVFE KYAETFKSLD VNPNDGLASL 300
YDKIAGIAQE ADIKVDIEHV LNESSRVAMV NSDKGITNFH VPSDVIVDAS 350
MAALVRGGGK MWNKDGQEED TLAIIPDRSY AGFYQAVIDD MKANGKLDPT 400
TMGSVPNVGL MAKKAEEYGS HDKTFQMEAE GTVKVLNENN EVLLEQKVET 450
GDIFRMCQTK DAPIQDWVKL AVNRSRLSDT PAIFWLDKGR AHDREVIKKV 500
EQYLKNYDTQ GLDIKILDVK DAMSETLKRA REGKDTISVS GNVLRDYLTD 550
LFPILELGTS AKMLSIVPLM NGGGLFETGA GGSAPKHIEQ FIEEGYLRWD 600
SLGEFLALQA SLEHLAQTQN NTKAQVLADA LDEANAKFLA NDKSPARKIG 650
SIDNRGSHFY LALYWAEALA AQTQDSELST LFQPIAKEMQ ENEAKINEEL 700
IASQGKAQDI EGYYRPNEDK TYAAMRPSVT LNQIIDRI 738
Length:738
Mass (Da):81,657
Last modified:February 8, 2011 - v1
Checksum:iB56B3E43408AFD12
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002346 Genomic DNA. Translation: ADQ81372.1.
CP003388 Genomic DNA. Translation: AFD55390.1.
RefSeqiYP_004044878.1. NC_014738.1.
YP_005393933.1. NC_017045.1.

Genome annotation databases

EnsemblBacteriaiADQ81372; ADQ81372; Riean_0199.
AFD55390; AFD55390; RA0C_0407.
GeneIDi10000930.
11996829.
KEGGirai:RA0C_0407.
ran:Riean_0199.
PATRICi45351038. VBIRieAna155424_0201.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002346 Genomic DNA. Translation: ADQ81372.1 .
CP003388 Genomic DNA. Translation: AFD55390.1 .
RefSeqi YP_004044878.1. NC_014738.1.
YP_005393933.1. NC_017045.1.

3D structure databases

ProteinModelPortali E4T8V8.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADQ81372 ; ADQ81372 ; Riean_0199 .
AFD55390 ; AFD55390 ; RA0C_0407 .
GeneIDi 10000930.
11996829.
KEGGi rai:RA0C_0407.
ran:Riean_0199.
PATRICi 45351038. VBIRieAna155424_0201.

Phylogenomic databases

HOGENOMi HOG000240860.
KOi K00031.

Enzyme and pathway databases

BioCyci RANA693978:GHF6-200-MONOMER.

Family and domain databases

Gene3Di 3.40.718.10. 3 hits.
InterProi IPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
Pfami PF03971. IDH. 1 hit.
[Graphical view ]
PIRSFi PIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 11845 / DSM 15868 / JCM 9532 / NCTC 11014 and DSM 15868Imported.
  2. "Complete Genome Sequence of Riemerella anatipestifer Reference Strain."
    Wang X., Zhu D., Wang M., Cheng A., Jia R., Zhou Y., Chen Z., Luo Q., Liu F., Wang Y., Chen X.Y.
    J. Bacteriol. 194:3270-3271(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 11845Imported.
  3. "Riemerella anatipestifer ATCC 11845 Complete Genome."
    Cheng A.-C., Wang M.-S., Zhu D.-K., Wang X.-J.
    Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: ATCC 11845Imported.

Entry informationi

Entry nameiE4T8V8_RIEAD
AccessioniPrimary (citable) accession number: E4T8V8
Entry historyi
Integrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: September 3, 2014
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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