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E4T8V8

- E4T8V8_RIEAD

UniProt

E4T8V8 - E4T8V8_RIEAD

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Protein
Submitted name:

Isocitrate dehydrogenase, NADP-dependent

Gene

Riean_0199

Organism
Riemerella anatipestifer (strain ATCC 11845 / DSM 15868 / JCM 9532 / NCTC 11014)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi

Functioni

Cofactori

Note: Binds 1 magnesium or manganese ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei145 – 1451SubstrateUniRule annotation
Sitei255 – 2551Critical for catalysisUniRule annotation
Metal bindingi348 – 3481Magnesium or manganeseUniRule annotation
Sitei418 – 4181Critical for catalysisUniRule annotation
Binding sitei545 – 5451SubstrateUniRule annotation
Metal bindingi546 – 5461Magnesium or manganeseUniRule annotation
Metal bindingi550 – 5501Magnesium or manganeseUniRule annotation

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciRANA693978:GHF6-200-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Isocitrate dehydrogenase, NADP-dependentImported (EC:1.1.1.42Imported)
Submitted name:
Isocitrate dehydrogenase, nADP-dependentImported
Gene namesi
Ordered Locus Names:Riean_0199Imported
ORF Names:RA0C_0407Imported
OrganismiRiemerella anatipestifer (strain ATCC 11845 / DSM 15868 / JCM 9532 / NCTC 11014)Imported
Taxonomic identifieri693978 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceaeRiemerella
ProteomesiUP000008719: Chromosome, UP000010093: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 3030 PotentialImportedAdd
BLAST
Chaini31 – 738708 PotentialImportedPRO_5000661345Add
BLAST

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni132 – 1398Substrate bindingUniRule annotation

Keywords - Domaini

SignalImported

Phylogenomic databases

HOGENOMiHOG000240860.
KOiK00031.

Family and domain databases

Gene3Di3.40.718.10. 3 hits.
InterProiIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamiPF03971. IDH. 1 hit.
[Graphical view]
PIRSFiPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

E4T8V8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSTAKIYYTL TDEAPMLATH SFLPIVKAFA KSADIQIEVP DISLSGRILA
60 70 80 90 100
NFPEVLTEEQ RIPDALSQLG ELATKPEANI IKLPNISASI PQLNEAIEEL
110 120 130 140 150
QKKGFNVPNY PAEPKTEEEK EIKAKYAKVL GSAVNPVLRE GNSDRRAPKA
160 170 180 190 200
VKNYAKANPH RMGEWKSDSK TDVAHMNQGD FYGTETSTTV EKDGKFKIVF
210 220 230 240 250
FGNDGSEKVL KDYASLQAGE IIDSSVMNIK ALKTFVKEAI QEAKSRNVLL
260 270 280 290 300
SAHLKATMMK VSDPIIFGAI VETFFQEVFE KYAETFKSLD VNPNDGLASL
310 320 330 340 350
YDKIAGIAQE ADIKVDIEHV LNESSRVAMV NSDKGITNFH VPSDVIVDAS
360 370 380 390 400
MAALVRGGGK MWNKDGQEED TLAIIPDRSY AGFYQAVIDD MKANGKLDPT
410 420 430 440 450
TMGSVPNVGL MAKKAEEYGS HDKTFQMEAE GTVKVLNENN EVLLEQKVET
460 470 480 490 500
GDIFRMCQTK DAPIQDWVKL AVNRSRLSDT PAIFWLDKGR AHDREVIKKV
510 520 530 540 550
EQYLKNYDTQ GLDIKILDVK DAMSETLKRA REGKDTISVS GNVLRDYLTD
560 570 580 590 600
LFPILELGTS AKMLSIVPLM NGGGLFETGA GGSAPKHIEQ FIEEGYLRWD
610 620 630 640 650
SLGEFLALQA SLEHLAQTQN NTKAQVLADA LDEANAKFLA NDKSPARKIG
660 670 680 690 700
SIDNRGSHFY LALYWAEALA AQTQDSELST LFQPIAKEMQ ENEAKINEEL
710 720 730
IASQGKAQDI EGYYRPNEDK TYAAMRPSVT LNQIIDRI
Length:738
Mass (Da):81,657
Last modified:February 8, 2011 - v1
Checksum:iB56B3E43408AFD12
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002346 Genomic DNA. Translation: ADQ81372.1.
CP003388 Genomic DNA. Translation: AFD55390.1.
RefSeqiYP_004044878.1. NC_014738.1.
YP_005393933.1. NC_017045.1.

Genome annotation databases

EnsemblBacteriaiADQ81372; ADQ81372; Riean_0199.
AFD55390; AFD55390; RA0C_0407.
GeneIDi10000930.
11996829.
KEGGirai:RA0C_0407.
ran:Riean_0199.
PATRICi45351038. VBIRieAna155424_0201.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002346 Genomic DNA. Translation: ADQ81372.1 .
CP003388 Genomic DNA. Translation: AFD55390.1 .
RefSeqi YP_004044878.1. NC_014738.1.
YP_005393933.1. NC_017045.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADQ81372 ; ADQ81372 ; Riean_0199 .
AFD55390 ; AFD55390 ; RA0C_0407 .
GeneIDi 10000930.
11996829.
KEGGi rai:RA0C_0407.
ran:Riean_0199.
PATRICi 45351038. VBIRieAna155424_0201.

Phylogenomic databases

HOGENOMi HOG000240860.
KOi K00031.

Enzyme and pathway databases

BioCyci RANA693978:GHF6-200-MONOMER.

Family and domain databases

Gene3Di 3.40.718.10. 3 hits.
InterProi IPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
Pfami PF03971. IDH. 1 hit.
[Graphical view ]
PIRSFi PIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 11845 / DSM 15868 / JCM 9532 / NCTC 11014Imported and DSM 15868Imported.
  2. "Complete genome sequence of Riemerella anatipestifer reference strain."
    Wang X., Zhu D., Wang M., Cheng A., Jia R., Zhou Y., Chen Z., Luo Q., Liu F., Wang Y., Chen X.Y.
    J. Bacteriol. 194:3270-3271(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 11845Imported.
  3. "Riemerella anatipestifer ATCC 11845 Complete Genome."
    Cheng A.-C., Wang M.-S., Zhu D.-K., Wang X.-J.
    Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: ATCC 11845Imported.

Entry informationi

Entry nameiE4T8V8_RIEAD
AccessioniPrimary (citable) accession number: E4T8V8
Entry historyi
Integrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: November 26, 2014
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3