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E4SYG6

- E4SYG6_LACDN

UniProt

E4SYG6 - E4SYG6_LACDN

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Protein

Elongation factor Tu

Gene

tuf

Organism
Lactobacillus delbrueckii subsp. bulgaricus (strain ND02)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi20 – 278GTPUniRule annotation
Nucleotide bindingi82 – 865GTPUniRule annotation
Nucleotide bindingi137 – 1404GTPUniRule annotation

GO - Molecular functioni

  1. GTPase activity Source: InterPro
  2. GTP binding Source: UniProtKB-HAMAP
  3. translation elongation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Elongation factorUniRule annotation

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciLDEL767455:GHXE-731-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TuUniRule annotation
Short name:
EF-TuUniRule annotation
Gene namesi
Name:tufUniRule annotationImported
Ordered Locus Names:LDBND_0712Imported
OrganismiLactobacillus delbrueckii subsp. bulgaricus (strain ND02)Imported
Taxonomic identifieri767455 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
ProteomesiUP000008717: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Monomer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000229290.
KOiK02358.
OMAiDNIEMVG.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B.
InterProiIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. EFACTOR_GTP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E4SYG6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAEKEHYVRT KPHVNIGTIG HVDHGKTTLT AAITTVLAKK GLAQAEDYSQ
60 70 80 90 100
IDAAPEEKER GITINTAHVE YETEKRHYAH MDAPGHADYI KNMITGAAQM
110 120 130 140 150
DGAILVVAAT DGPMPQTREH ILLARQVGVN YIVVFLNKCD LVDDPELIDL
160 170 180 190 200
VEMEVRDLLS EYGYPGDDVP VVRGSALKAL EGDEEAQKKI EELMDVVDEY
210 220 230 240 250
IPTPERETDK PFLMPVEDVF TITGRGTVAS GRIDRGTVKV GDSVEIVGLV
260 270 280 290 300
EKVLTSVVTG LEMFHKTLDL GEAGDNVGVL LRGVDRDQIV RGQVLAAPGS
310 320 330 340 350
IKTHKTFKGQ VYILSKDEGG RHTPFFSDYR PQFYFHTTDI TGEIELPEGT
360 370 380 390
EMVMPGDNTE FSVTLIKPAA IEVGTKFTIR EGGRTVGAGQ VTEIDD
Length:396
Mass (Da):43,357
Last modified:February 8, 2011 - v1
Checksum:i7E480B843F956711
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002341 Genomic DNA. Translation: ADQ60759.1.
RefSeqiYP_004033736.1. NC_014727.1.

Genome annotation databases

EnsemblBacteriaiADQ60759; ADQ60759; LDBND_0712.
GeneIDi9990373.
KEGGilde:LDBND_0712.
PATRICi43080746. VBILacDel160915_0712.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002341 Genomic DNA. Translation: ADQ60759.1 .
RefSeqi YP_004033736.1. NC_014727.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADQ60759 ; ADQ60759 ; LDBND_0712 .
GeneIDi 9990373.
KEGGi lde:LDBND_0712.
PATRICi 43080746. VBILacDel160915_0712.

Phylogenomic databases

HOGENOMi HOG000229290.
KOi K02358.
OMAi DNIEMVG.

Enzyme and pathway databases

BioCyci LDEL767455:GHXE-731-MONOMER.

Family and domain databases

Gene3Di 3.40.50.300. 1 hit.
HAMAPi MF_00118_B. EF_Tu_B.
InterProi IPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view ]
Pfami PF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view ]
PRINTSi PR00315. ELONGATNFCT.
SUPFAMi SSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEi PS00301. EFACTOR_GTP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of Lactobacillus delbrueckii subsp. bulgaricus strain ND02."
    Chen W., Zhang H., Sun Z., Chen X., Guo Z., Wang J., Wu L., Zhang X., Zhou Z., Sun T., Wang L., Meng H.
    Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ND02Imported.

Entry informationi

Entry nameiE4SYG6_LACDN
AccessioniPrimary (citable) accession number: E4SYG6
Entry historyi
Integrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: October 29, 2014
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3