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E4SN66

- E4SN66_LACAR

UniProt

E4SN66 - E4SN66_LACAR

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Protein
Spermidine/putrescine import ATP-binding protein PotA
Gene
potA, LA2_03675
Organism
Lactobacillus amylovorus (strain GRL 1112)
Status
Unreviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system By similarity.UniRule annotationSAAS annotations

Catalytic activityi

ATP + H2O + polyamine(Out) = ADP + phosphate + polyamine(In).UniRule annotationSAAS annotations

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi37 – 448ATP By similarityUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. putrescine-importing ATPase activity Source: InterPro
  3. spermidine-importing ATPase activity Source: InterPro
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    HydrolaseUniRule annotationSAAS annotations

    Keywords - Biological processi

    TransportUniRule annotationSAAS annotations

    Keywords - Ligandi

    ATP-bindingUniRule annotationSAAS annotationsImported, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciLAMY695560:GI0Z-768-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Spermidine/putrescine import ATP-binding protein PotAUniRule annotation (EC:3.6.3.31UniRule annotation)
    Gene namesi
    Name:potAUniRule annotation
    Ordered Locus Names:LA2_03675Imported
    OrganismiLactobacillus amylovorus (strain GRL 1112)Imported
    Taxonomic identifieri695560 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
    ProteomesiUP000007033: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. ATP-binding cassette (ABC) transporter complex Source: UniProtKB-HAMAP
    Complete GO annotation...

    Keywords - Cellular componenti

    Cell membraneUniRule annotationSAAS annotations, Membrane

    Interactioni

    Subunit structurei

    The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD) By similarity.UniRule annotationSAAS annotations

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini4 – 235232ABC transporter By similarityUniRule annotation
    Add
    BLAST

    Sequence similaritiesi

    Belongs to the ABC transporter superfamily.UniRule annotation
    Contains 1 ABC transporter domain.UniRule annotation
    Contains ABC transporter domain.SAAS annotations

    Phylogenomic databases

    KOiK11072.
    OMAiYDEPVND.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    InterProiIPR003593. AAA+_ATPase.
    IPR017879. ABC_Sperm/Put_ATP-bd_PotA.
    IPR003439. ABC_transporter-like.
    IPR017871. ABC_transporter_CS.
    IPR008995. Mo/tungstate-bd_C_term_dom.
    IPR027417. P-loop_NTPase.
    IPR005893. Sp_pt_ABC_ATP-bd.
    IPR013611. Transp-assoc_OB_typ2.
    [Graphical view]
    PfamiPF00005. ABC_tran. 1 hit.
    PF08402. TOBE_2. 1 hit.
    [Graphical view]
    SMARTiSM00382. AAA. 1 hit.
    [Graphical view]
    SUPFAMiSSF50331. SSF50331. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR01187. potA. 1 hit.
    PROSITEiPS00211. ABC_TRANSPORTER_1. 1 hit.
    PS50893. ABC_TRANSPORTER_2. 1 hit.
    PS51305. POTA. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E4SN66-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDIIKLKHIT KQYDDGFVAL KDINLTIESG KFYSLLGPSG SGKSTILRII    50
    AGFTQPTDGK VYFDGKDITN LDAAKRHINT VFQNYALFPH LNVFENVAFG 100
    LKIKKKPMNE IKPAVKDALH MVQLDGYANR EISELSGGQQ QRVAIARAIV 150
    NEPKVLLLDE SLSALDKRLR KDMQFELRAI QKKLGITFIF VTHDQEEALS 200
    MSDEIFVLND GEIQQSGSPV AIYDEPVNDF VARFIGDSNI LSGRMIKDYE 250
    VEFANNKFKC ADGGIKPNEK VEVVIRPEDL DIVDPEKGKI VVTAQTQLFL 300
    GDHFEIKAID ADENEWLIHS TNGVKLGQRI GLFFDPEDIH VMRLNESQAD 350
    FDARIEKYEG DENED 365
    Length:365
    Mass (Da):41,108
    Last modified:February 8, 2011 - v1
    Checksum:i34ED46349EF16FA0
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002338 Genomic DNA. Translation: ADQ58713.1.
    RefSeqiYP_004031508.1. NC_014724.1.

    Genome annotation databases

    EnsemblBacteriaiADQ58713; ADQ58713; LA2_03675.
    GeneIDi10022753.
    KEGGilam:LA2_03675.
    PATRICi43076473. VBILacAmy150400_0732.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002338 Genomic DNA. Translation: ADQ58713.1 .
    RefSeqi YP_004031508.1. NC_014724.1.

    3D structure databases

    ModBasei Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADQ58713 ; ADQ58713 ; LA2_03675 .
    GeneIDi 10022753.
    KEGGi lam:LA2_03675.
    PATRICi 43076473. VBILacAmy150400_0732.

    Phylogenomic databases

    KOi K11072.
    OMAi YDEPVND.

    Enzyme and pathway databases

    BioCyci LAMY695560:GI0Z-768-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    InterProi IPR003593. AAA+_ATPase.
    IPR017879. ABC_Sperm/Put_ATP-bd_PotA.
    IPR003439. ABC_transporter-like.
    IPR017871. ABC_transporter_CS.
    IPR008995. Mo/tungstate-bd_C_term_dom.
    IPR027417. P-loop_NTPase.
    IPR005893. Sp_pt_ABC_ATP-bd.
    IPR013611. Transp-assoc_OB_typ2.
    [Graphical view ]
    Pfami PF00005. ABC_tran. 1 hit.
    PF08402. TOBE_2. 1 hit.
    [Graphical view ]
    SMARTi SM00382. AAA. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50331. SSF50331. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR01187. potA. 1 hit.
    PROSITEi PS00211. ABC_TRANSPORTER_1. 1 hit.
    PS50893. ABC_TRANSPORTER_2. 1 hit.
    PS51305. POTA. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of Lactobacillus amylovorus GRL1112."
      Kant R., Paulin L., Alatalo E., de Vos W.M., Palva A.
      J. Bacteriol. 193:789-790(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: GRL 1112Imported.

    Entry informationi

    Entry nameiE4SN66_LACAR
    AccessioniPrimary (citable) accession number: E4SN66
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 8, 2011
    Last sequence update: February 8, 2011
    Last modified: July 9, 2014
    This is version 23 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    External Data

    Dasty 3

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