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E4SN66 (E4SN66_LACAR) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 23. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Spermidine/putrescine import ATP-binding protein PotA HAMAP-Rule MF_01726

EC=3.6.3.31 HAMAP-Rule MF_01726
Gene names
Name:potA HAMAP-Rule MF_01726
Ordered Locus Names:LA2_03675 EMBL ADQ58713.1
OrganismLactobacillus amylovorus (strain GRL 1112) [Complete proteome] [HAMAP] EMBL ADQ58713.1
Taxonomic identifier695560 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus

Protein attributes

Sequence length365 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system By similarity. HAMAP-Rule MF_01726 SAAS SAAS005893

Catalytic activity

ATP + H2O + polyamine(Out) = ADP + phosphate + polyamine(In). HAMAP-Rule MF_01726 SAAS SAAS005893

Subunit structure

The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD) By similarity. HAMAP-Rule MF_01726 SAAS SAAS005893

Subcellular location

Cell membrane; Peripheral membrane protein By similarity HAMAP-Rule MF_01726.

Sequence similarities

Belongs to the ABC transporter superfamily. RuleBase RU000684

Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family. [View classification] HAMAP-Rule MF_01726

Contains 1 ABC transporter domain. HAMAP-Rule MF_01726

Contains ABC transporter domain. SAAS SAAS005893

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain4 – 235232ABC transporter By similarity HAMAP-Rule MF_01726
Nucleotide binding37 – 448ATP By similarity HAMAP-Rule MF_01726

Sequences

Sequence LengthMass (Da)Tools
E4SN66 [UniParc].

Last modified February 8, 2011. Version 1.
Checksum: 34ED46349EF16FA0

FASTA36541,108
        10         20         30         40         50         60 
MDIIKLKHIT KQYDDGFVAL KDINLTIESG KFYSLLGPSG SGKSTILRII AGFTQPTDGK 

        70         80         90        100        110        120 
VYFDGKDITN LDAAKRHINT VFQNYALFPH LNVFENVAFG LKIKKKPMNE IKPAVKDALH 

       130        140        150        160        170        180 
MVQLDGYANR EISELSGGQQ QRVAIARAIV NEPKVLLLDE SLSALDKRLR KDMQFELRAI 

       190        200        210        220        230        240 
QKKLGITFIF VTHDQEEALS MSDEIFVLND GEIQQSGSPV AIYDEPVNDF VARFIGDSNI 

       250        260        270        280        290        300 
LSGRMIKDYE VEFANNKFKC ADGGIKPNEK VEVVIRPEDL DIVDPEKGKI VVTAQTQLFL 

       310        320        330        340        350        360 
GDHFEIKAID ADENEWLIHS TNGVKLGQRI GLFFDPEDIH VMRLNESQAD FDARIEKYEG 


DENED 

« Hide

References

[1]"Genome sequence of Lactobacillus amylovorus GRL1112."
Kant R., Paulin L., Alatalo E., de Vos W.M., Palva A.
J. Bacteriol. 193:789-790(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: GRL 1112 EMBL ADQ58713.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002338 Genomic DNA. Translation: ADQ58713.1.
RefSeqYP_004031508.1. NC_014724.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADQ58713; ADQ58713; LA2_03675.
GeneID10022753.
KEGGlam:LA2_03675.
PATRIC43076473. VBILacAmy150400_0732.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK11072.
OMAYDEPVND.

Enzyme and pathway databases

BioCycLAMY695560:GI0Z-768-MONOMER.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
InterProIPR003593. AAA+_ATPase.
IPR017879. ABC_Sperm/Put_ATP-bd_PotA.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR008995. Mo/tungstate-bd_C_term_dom.
IPR027417. P-loop_NTPase.
IPR005893. Sp_pt_ABC_ATP-bd.
IPR013611. Transp-assoc_OB_typ2.
[Graphical view]
PfamPF00005. ABC_tran. 1 hit.
PF08402. TOBE_2. 1 hit.
[Graphical view]
SMARTSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMSSF50331. SSF50331. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR01187. potA. 1 hit.
PROSITEPS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
PS51305. POTA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameE4SN66_LACAR
AccessionPrimary (citable) accession number: E4SN66
Entry history
Integrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: July 9, 2014
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)