E4SKB3 (E4SKB3_LACAR) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Chromosome partition protein Smc HAMAP-Rule MF_01894

Gene names

Name:	smc HAMAP-Rule MF_01894
Ordered Locus Names:	LA2_07325 EMBL ADQ59386.1

Organism

Lactobacillus amylovorus (strain GRL 1112) [Complete proteome] [HAMAP]

Taxonomic identifier

695560 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Lactobacillales › Lactobacillaceae › Lactobacillus › Lactobacillus amylovorus

Protein attributes

Sequence length	1189 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for chromosome condensation and partitioning By similarity. HAMAP-Rule MF_01894
Subunit structure	Homodimer By similarity. HAMAP-Rule MF_01894
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_01894.
Domain	Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures By similarity. HAMAP-Rule MF_01894
Sequence similarities	Belongs to the SMC family. HAMAP-Rule MF_01894

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP-Rule MF_01894
Domain	Coiled coil HAMAP-Rule MF_01894
Ligand	ATP-binding HAMAP-Rule MF_01894 DNA-binding HAMAP-Rule MF_01894 Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	DNA recombination Inferred from electronic annotation. Source: InterPro DNA repair Inferred from electronic annotation. Source: InterPro DNA replication Inferred from electronic annotation. Source: HAMAP chromosome condensation Inferred from electronic annotation. Source: InterPro sister chromatid cohesion Inferred from electronic annotation. Source: InterPro
Cellular_component	chromosome Inferred from electronic annotation. Source: InterPro cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: HAMAP DNA binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	32 – 39	8	ATP By similarity HAMAP-Rule MF_01894
	Coiled coil	167 – 492	326	By similarity HAMAP-Rule MF_01894
	Coiled coil	671 – 907	237	By similarity HAMAP-Rule MF_01894
	Coiled coil	1005 – 1033	29	By similarity HAMAP-Rule MF_01894

Sequences

	Sequence		Length	Mass (Da)
	E4SKB3 [UniParc]. Last modified February 8, 2011. Version 1. Checksum: 3A989545D0729E13	FASTA	1,189	134,689
	10 20 30 40 50 60 MPLTELVLDG FKSFAEKTTI HFNDGITGIV GPNGSGKSNI TEAIRWVMGE SSAKSLRGTN 70 80 90 100 110 120 MKDVIFAGSQ YRKPLNKAEV TLVFDNKDRE LAFDADQVSI TRRILRSGDS EFLINNQQVR 130 140 150 160 170 180 MRDVRALFLD SGISPNSLAI ISQGRVDQIL NSRPEQRRLI FEEAAGVLHF KQQKEEAQTQ 190 200 210 220 230 240 LKKTQDNLIR INDLVKELEG RLEPLHEQSS LAKEYQFQKA GLDKKLKSLL AFEIEDINRQ 250 260 270 280 290 300 KEDVEKSAKK SQVLLSKLDN EVKDSQDAVS EKRGEYKKLQ TERDNTQKQL LELSKKLSDL 310 320 330 340 350 360 DASLQMAEQS RQFDDATKVE YQNQVKSLKN SLVKLNEDLA SLQKNATELK DKQAVLQKQR 370 380 390 400 410 420 DELTAELKED PEELNKKLES CRNDYIQLLQ DQATTNNQIV NLNTELKRSK ADTSYQNSDV 430 440 450 460 470 480 SKQLSEAKTE LEKLRAEGKT LTEKRKSEKI KLAEVGDQNS DLTNKVNQLR QTVANERGKL 490 500 510 520 530 540 EKIEARHEAL VNIQKRHEGY YYGVRNVLNN MNAFPGVIGA VGELISFPVE LEAAMTTALG 550 560 570 580 590 600 GGVQDLITDS RISARNAINQ LKRNRAGRAT FLPLDGLRQY GIPQSTVTTL ESYEGFRGVA 610 620 630 640 650 660 SDLVESKTEH NINAAINYLL GSVIIVDTID TALSISKRIN RYRIVTLDGD VISPGGSMTG 670 680 690 700 710 720 GQRNQRNNSP LQTATEINQL EAQIKTLTKT LREDQNQLET LVDQAQRANA ELQKLQSSLQ 730 740 750 760 770 780 ETNQAINEVA ISFQSQEKEV KRLTDANNLY ESRIKERDSR IKELKQQIEE AQTKQNELTK 790 800 810 820 830 840 QGKEQRTAMN QLQERIRNFN SLSQKVQDQL SKLDPDIAVY TNKLENLRSQ ENEKKQQIRN 850 860 870 880 890 900 NQEQTADLTH KLQDLTQSGE RSVQKNTDLK KQKADLKQQT EDLQTKLNEL SSQLGQFDAQ 910 920 930 940 950 960 INQLDQVASR NYELRKDAAI EQEGYSVQLA KFNSAINQRL ETLRDDYSLT YEAALAQAEG 970 980 990 1000 1010 1020 ENDEDTRNEL AKSVKLHRMS IEDIGPVNLD SIQEYEDVKK RYDFLSGQQN DLLKARDDLE 1030 1040 1050 1060 1070 1080 KSMNELDEEV KTRFKDTFNT IADSFKQIFP VVFGGGKAKL ELTEPNNLLE TGIEIIAQPP 1090 1100 1110 1120 1130 1140 GKKLQRLSLL SGGERALTAI TLLFAMLQVN PVPFCVLDEV EAALDDANVT RFAQFLLKYD 1150 1160 1170 1180 MKTQFIVITH RRGTMRKADQ LYGVVMQESG VSQVLSVSLK ELKNKHEVR

References

[1]	"Genome sequence of Lactobacillus amylovorus GRL1112." Kant R., Paulin L., Alatalo E., de Vos W.M., Palva A. J. Bacteriol. 193:789-790(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: GRL 1112 EMBL ADQ59386.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002338 Genomic DNA. Translation: ADQ59386.1.
RefSeq	YP_004032181.1. NC_014724.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADQ59386; ADQ59386; LA2_07325.
GeneID	10023429.
KEGG	lam:LA2_07325.
PATRIC	43077908. VBILacAmy150400_1444.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000036392.
KO	K03529.
OMA	NNEVHAL.
Enzyme and pathway databases
BioCyc	LAMY695560:GI0Z-1511-MONOMER.
Family and domain databases
HAMAP	MF_01894. Smc_prok.
InterPro	IPR003395. RecF/RecN/SMC. IPR024704. SMC. IPR010935. SMC_hinge. IPR011890. SMC_prok. [Graphical view]
Pfam	PF06470. SMC_hinge. 1 hit. PF02463. SMC_N. 2 hits. [Graphical view]
PIRSF	PIRSF005719. SMC. 1 hit.
SMART	SM00968. SMC_hinge. 1 hit. [Graphical view]
SUPFAM	SSF75553. SMC_hinge. 1 hit.
TIGRFAMs	TIGR02168. SMC_prok_B. 1 hit.
ProtoNet	Search...

Entry information

Entry name

E4SKB3_LACAR

Accession

Primary (citable) accession number: E4SKB3

Entry history

Integrated into UniProtKB/TrEMBL:	February 8, 2011
Last sequence update:	February 8, 2011
Last modified:	May 1, 2013
This is version 17 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)