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E4SJ36

- E4SJ36_LACAR

UniProt

E4SJ36 - E4SJ36_LACAR

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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Lactobacillus amylovorus (strain GRL 1112)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Magnesium.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei138 – 1381UniRule annotation
Active sitei575 – 5751UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciLAMY695560:GI0Z-1243-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:LA2_06170Imported
OrganismiLactobacillus amylovorus (strain GRL 1112)Imported
Taxonomic identifieri695560 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
ProteomesiUP000007033: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000238647.
KOiK01595.
OMAiSILNCET.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E4SJ36-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTFTKLENSG DQAVVAEEVK ILTNLLNEST RQLIGDEKFA KIQDLINISA
60 70 80 90 100
SKDQRQLEEK ISSLNNREMI VVARYFATLP LLINISEDVE LASKVNVFNN
110 120 130 140 150
TDQDYLGKLS DTIDLVAKKD DAKRILENVN VVPVLTAHPT QIQRKTVLEL
160 170 180 190 200
TDKIHHLLRS YRDGKNGTIN QKEWTEQLRA CIEILMQTDI IRGHKLKVSN
210 220 230 240 250
EITNVLAYYP KALIPAITKF TARYKELAKE HDLALDHATP ITMGMWIGGD
260 270 280 290 300
RDGNPYVTAD TLELSATLQS QVIFEYYMKE LKKLYRAISL STSYMHPSAA
310 320 330 340 350
VEKLSELSND DSPFRTNEPY RRAFYYIESR LVHTEKQLLG VVDKNIFIKP
360 370 380 390 400
RDLENLENIP VYNDPQEFKA DLETIKASLD EDHDQAVTHS FFTEILEAID
410 420 430 440 450
VFGFHLATID MRQDSSVNEA CVAELLKSAG ICDDYSDLSE DEKIKLLLNE
460 470 480 490 500
LENDPRNLHA NNKPKSELLQ KELKIYKTAR QLKDRLGEDV IKQHIISHTE
510 520 530 540 550
SVSDMLEQAV MLKEYDLLDN EKARVQVVPL FETVEDLLNA REIITEYLNF
560 570 580 590 600
PIVKKWLASQ NNYQEIMLGY SDSNKDGGYL ASCWNLYKAQ RDLTAIGEKM
610 620 630 640 650
GVKITYMHGR GGTVGRGGGP SYDAITAQPF KSINDRIRMT EQGEIIQNKY
660 670 680 690 700
GNKDTAYYNL EMLASAAIDR MVSKQIVSED HIQEFRSSMD KIVDESNKIY
710 720 730 740 750
RKLVFENPAF LDFFFQATPI KEISNLNIGS RPASRKKLTD FSGLRAIPWV
760 770 780 790 800
FSWSQSRIMF PGWYGVGSAF KHFIDADPNN LKELQEMYKG WPFFNSLLSN
810 820 830 840 850
VDMVLSKSNM DIAREYANLC DDEETMKVFD IIYKEWKLTK KVILQIENHD
860 870 880 890 900
ELLAEAPVLK QSLDYRMPYF NILNYIQIEM IKRGREDEIQ GVYHSIIPIT
910
INGVASGLRN SG
Length:912
Mass (Da):104,442
Last modified:February 8, 2011 - v1
Checksum:i762E13BC09644288
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002338 Genomic DNA. Translation: ADQ59185.1.
RefSeqiWP_013437980.1. NC_014724.1.
YP_004031980.1. NC_014724.1.

Genome annotation databases

EnsemblBacteriaiADQ59185; ADQ59185; LA2_06170.
GeneIDi10023228.
KEGGilam:LA2_06170.
PATRICi43077442. VBILacAmy150400_1212.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002338 Genomic DNA. Translation: ADQ59185.1 .
RefSeqi WP_013437980.1. NC_014724.1.
YP_004031980.1. NC_014724.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADQ59185 ; ADQ59185 ; LA2_06170 .
GeneIDi 10023228.
KEGGi lam:LA2_06170.
PATRICi 43077442. VBILacAmy150400_1212.

Phylogenomic databases

HOGENOMi HOG000238647.
KOi K01595.
OMAi SILNCET.

Enzyme and pathway databases

BioCyci LAMY695560:GI0Z-1243-MONOMER.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of Lactobacillus amylovorus GRL1112."
    Kant R., Paulin L., Alatalo E., de Vos W.M., Palva A.
    J. Bacteriol. 193:789-790(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: GRL 1112Imported.

Entry informationi

Entry nameiE4SJ36_LACAR
AccessioniPrimary (citable) accession number: E4SJ36
Entry historyi
Integrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: October 29, 2014
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3