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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Lactobacillus amylovorus (strain GRL 1112)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei138UniRule annotation1
Active sitei575UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotationSAAS annotationImported
Biological processCarbon dioxide fixationUniRule annotationSAAS annotation
LigandMagnesiumUniRule annotationSAAS annotation, PyruvateImported

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:LA2_06170Imported
OrganismiLactobacillus amylovorus (strain GRL 1112)Imported
Taxonomic identifieri695560 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
Proteomesi
  • UP000007033 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili47 – 67Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

HOGENOMiHOG000238647
KOiK01595
OMAiPWVFGWT
OrthoDBiPOG091H040O

Family and domain databases

HAMAPiMF_00595 PEPcase_type1, 1 hit
InterProiView protein in InterPro
IPR021135 PEP_COase
IPR022805 PEP_COase_bac/pln-type
IPR018129 PEP_COase_Lys_AS
IPR033129 PEPCASE_His_AS
IPR015813 Pyrv/PenolPyrv_Kinase-like_dom
PANTHERiPTHR30523 PTHR30523, 1 hit
PfamiView protein in Pfam
PF00311 PEPcase, 1 hit
PRINTSiPR00150 PEPCARBXLASE
SUPFAMiSSF51621 SSF51621, 1 hit
PROSITEiView protein in PROSITE
PS00781 PEPCASE_1, 1 hit
PS00393 PEPCASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

E4SJ36-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTFTKLENSG DQAVVAEEVK ILTNLLNEST RQLIGDEKFA KIQDLINISA
60 70 80 90 100
SKDQRQLEEK ISSLNNREMI VVARYFATLP LLINISEDVE LASKVNVFNN
110 120 130 140 150
TDQDYLGKLS DTIDLVAKKD DAKRILENVN VVPVLTAHPT QIQRKTVLEL
160 170 180 190 200
TDKIHHLLRS YRDGKNGTIN QKEWTEQLRA CIEILMQTDI IRGHKLKVSN
210 220 230 240 250
EITNVLAYYP KALIPAITKF TARYKELAKE HDLALDHATP ITMGMWIGGD
260 270 280 290 300
RDGNPYVTAD TLELSATLQS QVIFEYYMKE LKKLYRAISL STSYMHPSAA
310 320 330 340 350
VEKLSELSND DSPFRTNEPY RRAFYYIESR LVHTEKQLLG VVDKNIFIKP
360 370 380 390 400
RDLENLENIP VYNDPQEFKA DLETIKASLD EDHDQAVTHS FFTEILEAID
410 420 430 440 450
VFGFHLATID MRQDSSVNEA CVAELLKSAG ICDDYSDLSE DEKIKLLLNE
460 470 480 490 500
LENDPRNLHA NNKPKSELLQ KELKIYKTAR QLKDRLGEDV IKQHIISHTE
510 520 530 540 550
SVSDMLEQAV MLKEYDLLDN EKARVQVVPL FETVEDLLNA REIITEYLNF
560 570 580 590 600
PIVKKWLASQ NNYQEIMLGY SDSNKDGGYL ASCWNLYKAQ RDLTAIGEKM
610 620 630 640 650
GVKITYMHGR GGTVGRGGGP SYDAITAQPF KSINDRIRMT EQGEIIQNKY
660 670 680 690 700
GNKDTAYYNL EMLASAAIDR MVSKQIVSED HIQEFRSSMD KIVDESNKIY
710 720 730 740 750
RKLVFENPAF LDFFFQATPI KEISNLNIGS RPASRKKLTD FSGLRAIPWV
760 770 780 790 800
FSWSQSRIMF PGWYGVGSAF KHFIDADPNN LKELQEMYKG WPFFNSLLSN
810 820 830 840 850
VDMVLSKSNM DIAREYANLC DDEETMKVFD IIYKEWKLTK KVILQIENHD
860 870 880 890 900
ELLAEAPVLK QSLDYRMPYF NILNYIQIEM IKRGREDEIQ GVYHSIIPIT
910
INGVASGLRN SG
Length:912
Mass (Da):104,442
Last modified:February 8, 2011 - v1
Checksum:i762E13BC09644288
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002338 Genomic DNA Translation: ADQ59185.1
RefSeqiWP_013437980.1, NC_014724.1

Genome annotation databases

EnsemblBacteriaiADQ59185; ADQ59185; LA2_06170
KEGGilam:LA2_06170
PATRICifig|695560.3.peg.1212

Similar proteinsi

Entry informationi

Entry nameiE4SJ36_LACAR
AccessioniPrimary (citable) accession number: E4SJ36
Entry historyiIntegrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: March 28, 2018
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health