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E4SJ36

- E4SJ36_LACAR

UniProt

E4SJ36 - E4SJ36_LACAR

Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Lactobacillus amylovorus (strain GRL 1112)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 23 (01 Oct 2014)
      Sequence version 1 (08 Feb 2011)
      Previous versions | rss
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    Functioni

    Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

    Catalytic activityi

    Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

    Cofactori

    Magnesium.UniRule annotationSAAS annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei138 – 1381UniRule annotation
    Active sitei575 – 5751UniRule annotation

    GO - Molecular functioni

    1. magnesium ion binding Source: UniProtKB-HAMAP
    2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. carbon fixation Source: UniProtKB-HAMAP
    2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
    3. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    LyaseUniRule annotationSAAS annotationImported

    Keywords - Biological processi

    Carbon dioxide fixationUniRule annotationSAAS annotation

    Keywords - Ligandi

    MagnesiumUniRule annotationSAAS annotation, PyruvateImported

    Enzyme and pathway databases

    BioCyciLAMY695560:GI0Z-1243-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
    Short name:
    PEPCUniRule annotation
    Short name:
    PEPCaseUniRule annotation
    Gene namesi
    Name:ppcUniRule annotation
    Ordered Locus Names:LA2_06170Imported
    OrganismiLactobacillus amylovorus (strain GRL 1112)Imported
    Taxonomic identifieri695560 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
    ProteomesiUP000007033: Chromosome

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotation

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PEPCase type 1 family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000238647.
    KOiK01595.
    OMAiSILNCET.

    Family and domain databases

    HAMAPiMF_00595. PEPcase_type1.
    InterProiIPR021135. PEP_COase.
    IPR018129. PEP_COase_AS.
    IPR022805. PEP_COase_bac/pln-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view]
    PfamiPF00311. PEPcase. 1 hit.
    [Graphical view]
    PRINTSiPR00150. PEPCARBXLASE.
    SUPFAMiSSF51621. SSF51621. 1 hit.
    PROSITEiPS00781. PEPCASE_1. 1 hit.
    PS00393. PEPCASE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E4SJ36-1 [UniParc]FASTAAdd to Basket

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    MTFTKLENSG DQAVVAEEVK ILTNLLNEST RQLIGDEKFA KIQDLINISA    50
    SKDQRQLEEK ISSLNNREMI VVARYFATLP LLINISEDVE LASKVNVFNN 100
    TDQDYLGKLS DTIDLVAKKD DAKRILENVN VVPVLTAHPT QIQRKTVLEL 150
    TDKIHHLLRS YRDGKNGTIN QKEWTEQLRA CIEILMQTDI IRGHKLKVSN 200
    EITNVLAYYP KALIPAITKF TARYKELAKE HDLALDHATP ITMGMWIGGD 250
    RDGNPYVTAD TLELSATLQS QVIFEYYMKE LKKLYRAISL STSYMHPSAA 300
    VEKLSELSND DSPFRTNEPY RRAFYYIESR LVHTEKQLLG VVDKNIFIKP 350
    RDLENLENIP VYNDPQEFKA DLETIKASLD EDHDQAVTHS FFTEILEAID 400
    VFGFHLATID MRQDSSVNEA CVAELLKSAG ICDDYSDLSE DEKIKLLLNE 450
    LENDPRNLHA NNKPKSELLQ KELKIYKTAR QLKDRLGEDV IKQHIISHTE 500
    SVSDMLEQAV MLKEYDLLDN EKARVQVVPL FETVEDLLNA REIITEYLNF 550
    PIVKKWLASQ NNYQEIMLGY SDSNKDGGYL ASCWNLYKAQ RDLTAIGEKM 600
    GVKITYMHGR GGTVGRGGGP SYDAITAQPF KSINDRIRMT EQGEIIQNKY 650
    GNKDTAYYNL EMLASAAIDR MVSKQIVSED HIQEFRSSMD KIVDESNKIY 700
    RKLVFENPAF LDFFFQATPI KEISNLNIGS RPASRKKLTD FSGLRAIPWV 750
    FSWSQSRIMF PGWYGVGSAF KHFIDADPNN LKELQEMYKG WPFFNSLLSN 800
    VDMVLSKSNM DIAREYANLC DDEETMKVFD IIYKEWKLTK KVILQIENHD 850
    ELLAEAPVLK QSLDYRMPYF NILNYIQIEM IKRGREDEIQ GVYHSIIPIT 900
    INGVASGLRN SG 912
    Length:912
    Mass (Da):104,442
    Last modified:February 8, 2011 - v1
    Checksum:i762E13BC09644288
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002338 Genomic DNA. Translation: ADQ59185.1.
    RefSeqiYP_004031980.1. NC_014724.1.

    Genome annotation databases

    EnsemblBacteriaiADQ59185; ADQ59185; LA2_06170.
    GeneIDi10023228.
    KEGGilam:LA2_06170.
    PATRICi43077442. VBILacAmy150400_1212.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002338 Genomic DNA. Translation: ADQ59185.1 .
    RefSeqi YP_004031980.1. NC_014724.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADQ59185 ; ADQ59185 ; LA2_06170 .
    GeneIDi 10023228.
    KEGGi lam:LA2_06170.
    PATRICi 43077442. VBILacAmy150400_1212.

    Phylogenomic databases

    HOGENOMi HOG000238647.
    KOi K01595.
    OMAi SILNCET.

    Enzyme and pathway databases

    BioCyci LAMY695560:GI0Z-1243-MONOMER.

    Family and domain databases

    HAMAPi MF_00595. PEPcase_type1.
    InterProi IPR021135. PEP_COase.
    IPR018129. PEP_COase_AS.
    IPR022805. PEP_COase_bac/pln-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view ]
    Pfami PF00311. PEPcase. 1 hit.
    [Graphical view ]
    PRINTSi PR00150. PEPCARBXLASE.
    SUPFAMi SSF51621. SSF51621. 1 hit.
    PROSITEi PS00781. PEPCASE_1. 1 hit.
    PS00393. PEPCASE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of Lactobacillus amylovorus GRL1112."
      Kant R., Paulin L., Alatalo E., de Vos W.M., Palva A.
      J. Bacteriol. 193:789-790(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: GRL 1112Imported.

    Entry informationi

    Entry nameiE4SJ36_LACAR
    AccessioniPrimary (citable) accession number: E4SJ36
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 8, 2011
    Last sequence update: February 8, 2011
    Last modified: October 1, 2014
    This is version 23 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3