ID   E4SFV2_CALK2            Unreviewed;       393 AA.
AC   E4SFV2;
DT   08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT   08-FEB-2011, sequence version 1.
DT   27-MAR-2024, entry version 48.
DE   SubName: Full=Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein {ECO:0000313|EMBL:ADQ46627.1};
GN   OrderedLocusNames=Calkro_1778 {ECO:0000313|EMBL:ADQ46627.1};
OS   Caldicellulosiruptor kronotskyensis (strain DSM 18902 / VKM B-2412 / 2002).
OC   Bacteria; Bacillota; Clostridia; Caldicellulosiruptorales;
OC   Caldicellulosiruptoraceae; Caldicellulosiruptor.
OX   NCBI_TaxID=632348 {ECO:0000313|EMBL:ADQ46627.1, ECO:0000313|Proteomes:UP000006835};
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=2002;
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA   Pitluck S., Davenport K., Detter J.C., Han C., Tapia R., Land M.,
RA   Hauser L., Jeffries C., Kyrpides N., Ivanova N., Mikhailova N.,
RA   Blumer-Schuette S.E., Kelly R.M., Woyke T.;
RT   "Complete sequence of Caldicellulosiruptor kronotskyensis 2002.";
RL   Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ADQ46627.1, ECO:0000313|Proteomes:UP000006835}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 18902 / VKM B-2412 / 2002
RC   {ECO:0000313|Proteomes:UP000006835};
RX   PubMed=21216991; DOI=10.1128/JB.01515-10;
RA   Blumer-Schuette S.E., Ozdemir I., Mistry D., Lucas S., Lapidus A.,
RA   Cheng J.F., Goodwin L.A., Pitluck S., Land M.L., Hauser L.J., Woyke T.,
RA   Mikhailova N., Pati A., Kyrpides N.C., Ivanova N., Detter J.C.,
RA   Walston-Davenport K., Han S., Adams M.W., Kelly R.M.;
RT   "Complete genome sequences for the anaerobic, extremely thermophilic plant
RT   biomass-degrading bacteria Caldicellulosiruptor hydrothermalis,
RT   Caldicellulosiruptor kristjanssonii, Caldicellulosiruptor kronotskyensis,
RT   Caldicellulosiruptor owensenis, and Caldicellulosiruptor lactoaceticus.";
RL   J. Bacteriol. 193:1483-1484(2011).
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DR   EMBL; CP002330; ADQ46627.1; -; Genomic_DNA.
DR   RefSeq; WP_013430715.1; NC_014720.1.
DR   AlphaFoldDB; E4SFV2; -.
DR   KEGG; ckn:Calkro_1778; -.
DR   PATRIC; fig|632348.3.peg.1875; -.
DR   HOGENOM; CLU_002569_5_0_9; -.
DR   OrthoDB; 9794954at2; -.
DR   Proteomes; UP000006835; Chromosome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   CDD; cd07034; TPP_PYR_PFOR_IOR-alpha_like; 1.
DR   Gene3D; 3.40.50.920; -; 1.
DR   Gene3D; 3.40.50.970; -; 1.
DR   InterPro; IPR033412; PFOR_II.
DR   InterPro; IPR002880; Pyrv_Fd/Flavodoxin_OxRdtase_N.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR009014; Transketo_C/PFOR_II.
DR   PANTHER; PTHR32154; PYRUVATE-FLAVODOXIN OXIDOREDUCTASE-RELATED; 1.
DR   PANTHER; PTHR32154:SF0; PYRUVATE-FLAVODOXIN OXIDOREDUCTASE-RELATED; 1.
DR   Pfam; PF17147; PFOR_II; 1.
DR   Pfam; PF01855; POR_N; 1.
DR   SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR   SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE   4: Predicted;
KW   Pyruvate {ECO:0000313|EMBL:ADQ46627.1}.
FT   DOMAIN          16..240
FT                   /note="Pyruvate flavodoxin/ferredoxin oxidoreductase
FT                   pyrimidine binding"
FT                   /evidence="ECO:0000259|Pfam:PF01855"
FT   DOMAIN          262..366
FT                   /note="Pyruvate:ferredoxin oxidoreductase core"
FT                   /evidence="ECO:0000259|Pfam:PF17147"
SQ   SEQUENCE   393 AA;  43333 MW;  D4E7D2E7BC01C406 CRC64;
     MAIRDRLSGN EAIALAMKQI NPDVVAAFPI TPSTEVPQYF SQYVANGEVD TEFVAVESEH
     SAMSACIGAS AAGARTMTAT SSQGLALMWE MLYIAASMRL PIVMAVINRA LSGPINIHND
     HSDSMGARDS GWIQIYCENN QEAYDSLIQA IRIAEHKDVR LPVMVCYDGF ITSHAVENIE
     LLEDELVKKF VGEYNPEFYL LNEQNPISMG PLDLPPYYFE HKRQQAEAMR NAKKVVLEVA
     EEFAALTGRK YGLFESYKLD DAEVAIVVMN STAGTAKAVV DEYRSKGYKV GLLKPRLFRP
     FPVDEIVGVL KHLKAIAIMD KSDGFNAAGG PLFTEITSAL YGRADGIKAI NYIYGLGGRD
     VKTDDIAKVY DRLLDIVKTG NVGEVYNYIG VRE
//