Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Uridine kinase

Gene

Lbys_3067

Organism
Leadbetterella byssophila (strain DSM 17132 / KACC 11308 / 4M15)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + cytidine = ADP + CMP.SAAS annotation
ATP + uridine = ADP + UMP.SAAS annotation

Pathwayi: CTP biosynthesis via salvage pathway

This protein is involved in step 1 of the subpathway that synthesizes CTP from cytidine.SAAS annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. Uridine kinase (Lbys_3067)
  2. no protein annotated in this organism
  3. no protein annotated in this organism
This subpathway is part of the pathway CTP biosynthesis via salvage pathway, which is itself part of Pyrimidine metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes CTP from cytidine, the pathway CTP biosynthesis via salvage pathway and in Pyrimidine metabolism.

Pathwayi: UMP biosynthesis via salvage pathway

This protein is involved in step 1 of the subpathway that synthesizes UMP from uridine.SAAS annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Uridine kinase (Lbys_3067)
This subpathway is part of the pathway UMP biosynthesis via salvage pathway, which is itself part of Pyrimidine metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes UMP from uridine, the pathway UMP biosynthesis via salvage pathway and in Pyrimidine metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseSAAS annotationImported, Transferase
LigandATP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00574; UER00637.
UPA00579; UER00640.

Names & Taxonomyi

Protein namesi
Recommended name:
Uridine kinaseSAAS annotation (EC:2.7.1.48SAAS annotation)
Gene namesi
Ordered Locus Names:Lbys_3067Imported
OrganismiLeadbetterella byssophila (strain DSM 17132 / KACC 11308 / 4M15)Imported
Taxonomic identifieri649349 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesCytophagiaCytophagalesCytophagaceaeLeadbetterella
Proteomesi
  • UP000007435 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi649349.Lbys_3067.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 183PRKInterPro annotationAdd BLAST179

Sequence similaritiesi

Belongs to the uridine kinase family.SAAS annotation

Phylogenomic databases

eggNOGiENOG4105DBI. Bacteria.
COG0572. LUCA.
HOGENOMiHOG000262756.
KOiK00876.
OMAiTTLKPMH.
OrthoDBiPOG091H04CS.

Family and domain databases

CDDicd02023. UMPK. 1 hit.
InterProiView protein in InterPro
IPR027417. P-loop_NTPase.
IPR006083. PRK/URK.
IPR000764. Uridine_kinase-like.
PfamiView protein in Pfam
PF00485. PRK. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

E4RUJ3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEPYIIGITG GSASGKTFFL HSLLEHFQED EVCLISQDNY YKSKEHVPLD
60 70 80 90 100
QNGVFNFDLP ESIDFALFAQ HLQALKRGET VVMKEYTFEC DYEPKTITLH
110 120 130 140 150
PAPIIVVEGI FAFHDPVISK MLNLKIFIDA VEHVKIRRRI IRDTNERQYD
160 170 180 190 200
LDSILYRWEN HVAPTYERFI RPTKQDADII INNNRDFENG LKLLSVYLKS

LLVKEPA
Length:207
Mass (Da):24,090
Last modified:February 8, 2011 - v1
Checksum:iD4392A3285F9AAFB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002305 Genomic DNA. Translation: ADQ18729.1.

Genome annotation databases

EnsemblBacteriaiADQ18729; ADQ18729; Lbys_3067.
KEGGilby:Lbys_3067.

Similar proteinsi

Entry informationi

Entry nameiE4RUJ3_LEAB4
AccessioniPrimary (citable) accession number: E4RUJ3
Entry historyiIntegrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: September 27, 2017
This is version 42 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported