Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

E4RPE3

- E4RPE3_HALHG

UniProt

E4RPE3 - E4RPE3_HALHG

Protein

Alanine racemase

Gene

Halsa_0353

Organism
Halanaerobium hydrogeniformans (Halanaerobium sp. (strain sapolanicus))
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 28 (01 Oct 2014)
      Sequence version 1 (08 Feb 2011)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotationSAAS annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei43 – 431Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei141 – 1411SubstrateUniRule annotation
    Active sitei270 – 2701Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei318 – 3181Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciHHYD656519:GHYV-362-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Ordered Locus Names:Halsa_0353Imported
    OrganismiHalanaerobium hydrogeniformans (Halanaerobium sp. (strain sapolanicus))Imported
    Taxonomic identifieri656519 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesClostridiaHalanaerobialesHalanaerobiaceaeHalanaerobium
    ProteomesiUP000007434: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei43 – 431N6-(pyridoxal phosphate)lysineUniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliE4RPE3.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    KOiK01775.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.
    PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E4RPE3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLKKLEKSKR PVWVEIDLNN LKFNIKEIKK TLNSDTIFTA VVKADGYGHG    50
    AVPTAEAAIE AGADRLAVAI PEEGIELREA GIAAPIEILG ELLPEQLPEL 100
    IRYDLIPTIS KFKTAERLNN LCAGYNLKKK IHLNIDTGMN RVGVNYKKAL 150
    PLLKKITELP NLEIEGIMTH FARADELEKE YTLIQWERFN QLIEKLEAEN 200
    IEIPIKHCAN SAAVIDFPEF ALDMVRAGIM IYGLKPSPDL KNNFNLKAVL 250
    SWKSRIVRLK DVPAGEGISY GSEYITPKRE KIATIPLGYA DGYARILGNK 300
    ASVLVKGKRA PIRGRICMDQ FMVDVSGIEG VKVGDEVVLI GSQNGLSLSA 350
    DKLAEQAGTI NYEIVSRISK RVARIYK 377
    Length:377
    Mass (Da):41,849
    Last modified:February 8, 2011 - v1
    Checksum:iFD06B63011385E11
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002304 Genomic DNA. Translation: ADQ13828.1.
    RefSeqiWP_013404934.1. NC_014654.1.
    YP_003994182.1. NC_014654.1.

    Genome annotation databases

    EnsemblBacteriaiADQ13828; ADQ13828; Halsa_0353.
    GeneIDi9967943.
    KEGGihas:Halsa_0353.
    PATRICi42639256. VBIHalSp157090_0377.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002304 Genomic DNA. Translation: ADQ13828.1 .
    RefSeqi WP_013404934.1. NC_014654.1.
    YP_003994182.1. NC_014654.1.

    3D structure databases

    ProteinModelPortali E4RPE3.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADQ13828 ; ADQ13828 ; Halsa_0353 .
    GeneIDi 9967943.
    KEGGi has:Halsa_0353.
    PATRICi 42639256. VBIHalSp157090_0377.

    Phylogenomic databases

    KOi K01775.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci HHYD656519:GHYV-362-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: sapolanicusImported.

    Entry informationi

    Entry nameiE4RPE3_HALHG
    AccessioniPrimary (citable) accession number: E4RPE3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 8, 2011
    Last sequence update: February 8, 2011
    Last modified: October 1, 2014
    This is version 28 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3