E4RPE3 (E4RPE3_HALSL) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Alanine racemase RuleBase RU000608
EC=5.1.1.1 RuleBase RU000608

Gene names

Name:	alr
Ordered Locus Names:	Halsa_0353

Organism

Halanaerobium sp. (strain sapolanicus) [Complete proteome] [HAMAP]

Taxonomic identifier

656519 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Clostridia › Halanaerobiales › Halanaerobiaceae › Halanaerobium

Protein attributes

Sequence length	377 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-alanine = D-alanine. RuleBase RU000608 SAAS SAAS020622
Cofactor	Pyridoxal phosphate By similarity. RuleBase RU000608 SAAS SAAS020622
Pathway	Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. RuleBase RU004247 SAAS SAAS020622
Sequence similarities	Belongs to the alanine racemase family. RuleBase RU004188

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU000608 SAAS SAAS020622
Molecular function	Isomerase SAAS SAAS020622 RuleBase RU000608 EMBL ADQ13828.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	D-alanine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	alanine racemase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	E4RPE3 [UniParc]. Last modified February 8, 2011. Version 1. Checksum: FD06B63011385E11	FASTA	377	41,849
	10 20 30 40 50 60 MLKKLEKSKR PVWVEIDLNN LKFNIKEIKK TLNSDTIFTA VVKADGYGHG AVPTAEAAIE 70 80 90 100 110 120 AGADRLAVAI PEEGIELREA GIAAPIEILG ELLPEQLPEL IRYDLIPTIS KFKTAERLNN 130 140 150 160 170 180 LCAGYNLKKK IHLNIDTGMN RVGVNYKKAL PLLKKITELP NLEIEGIMTH FARADELEKE 190 200 210 220 230 240 YTLIQWERFN QLIEKLEAEN IEIPIKHCAN SAAVIDFPEF ALDMVRAGIM IYGLKPSPDL 250 260 270 280 290 300 KNNFNLKAVL SWKSRIVRLK DVPAGEGISY GSEYITPKRE KIATIPLGYA DGYARILGNK 310 320 330 340 350 360 ASVLVKGKRA PIRGRICMDQ FMVDVSGIEG VKVGDEVVLI GSQNGLSLSA DKLAEQAGTI 370 NYEIVSRISK RVARIYK

References

[1]

"Complete sequence of Halanaerobium sp. sapolanicus." US DOE Joint Genome Institute Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., Pitluck S., Davenport K., Detter J.C., Han C., Tapia R., Land M., Hauser L., Jeffries C., Kyrpides N., Ivanova N., Mikhailova N., Begemann M.B. , Mormile M.R., Wall J.D., Elias D.A., Woyke T. Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: sapolanicus.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002304 Genomic DNA. Translation: ADQ13828.1.
RefSeq	YP_003994182.1. NC_014654.1.
3D structure databases
ProteinModelPortal	E4RPE3.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADQ13828; ADQ13828; Halsa_0353.
GeneID	9967943.
KEGG	has:Halsa_0353.
PATRIC	42639256. VBIHalSp157090_0377.
Organism-specific databases
CMR	Search...
Phylogenomic databases
KO	K01775.
Enzyme and pathway databases
BioCyc	HHYD656519:GHYV-361-MONOMER.
UniPathway	UPA00042; UER00497.
Family and domain databases
Gene3D	2.40.37.10. 1 hit.
HAMAP	MF_01201. Ala_racemase.
InterPro	IPR000821. Ala_racemase. IPR009006. Ala_racemase/Decarboxylase_C. IPR011079. Ala_racemase_C. IPR001608. Ala_racemase_N. IPR020622. Ala_racemase_pyridoxalP-BS. [Graphical view]
Pfam	PF00842. Ala_racemase_C. 1 hit. PF01168. Ala_racemase_N. 1 hit. [Graphical view]
PRINTS	PR00992. ALARACEMASE.
SMART	SM01005. Ala_racemase_C. 1 hit. [Graphical view]
SUPFAM	SSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMs	TIGR00492. alr. 1 hit.
PROSITE	PS00395. ALANINE_RACEMASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

E4RPE3_HALSL

Accession

Primary (citable) accession number: E4RPE3

Entry history

Integrated into UniProtKB/TrEMBL:	February 8, 2011
Last sequence update:	February 8, 2011
Last modified:	May 1, 2013
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)