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E4RN22

- E4RN22_HALHG

UniProt

E4RN22 - E4RN22_HALHG

Protein
Submitted name:

Glycine dehydrogenase (Decarboxylating)

Gene

Halsa_0792

Organism
Halanaerobium hydrogeniformans (Halanaerobium sp. (strain sapolanicus))
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 24 (01 Oct 2014)
      Sequence version 1 (08 Feb 2011)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Glycine + H-protein-lipoyllysine = H-protein-S-aminomethyldihydrolipoyllysine + CO2.
    Glycine + [glycine-cleavage complex H protein]-N(6)-lipoyl-L-lysine = [glycine-cleavage complex H protein]-S-aminomethyl-N(6)-dihydrolipoyl-L-lysine + CO2.SAAS annotation

    Cofactori

    Pyridoxal phosphate.SAAS annotation

    GO - Molecular functioni

    1. glycine dehydrogenase (decarboxylating) activity Source: UniProtKB-EC
    2. pyridoxal phosphate binding Source: InterPro

    GO - Biological processi

    1. glycine catabolic process Source: InterPro

    Keywords - Molecular functioni

    OxidoreductaseSAAS annotationImported

    Keywords - Ligandi

    Pyridoxal phosphateSAAS annotation

    Enzyme and pathway databases

    BioCyciHHYD656519:GHYV-796-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Glycine dehydrogenase (Decarboxylating)Imported (EC:1.4.4.2Imported)
    Gene namesi
    Ordered Locus Names:Halsa_0792Imported
    OrganismiHalanaerobium hydrogeniformans (Halanaerobium sp. (strain sapolanicus))Imported
    Taxonomic identifieri656519 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesClostridiaHalanaerobialesHalanaerobiaceaeHalanaerobium
    ProteomesiUP000007434: Chromosome

    Interactioni

    Subunit structurei

    The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.SAAS annotation

    Family & Domainsi

    Phylogenomic databases

    KOiK00282.

    Family and domain databases

    Gene3Di3.40.640.10. 1 hit.
    InterProiIPR020580. GDC-P_N.
    IPR020581. GDC_P.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    [Graphical view]
    PANTHERiPTHR11773. PTHR11773. 1 hit.
    PfamiPF02347. GDC-P. 1 hit.
    [Graphical view]
    SUPFAMiSSF53383. SSF53383. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    E4RN22-1 [UniParc]FASTAAdd to Basket

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    MIIVKDDNIK GEEKKLAKRA FPYIPNSVEE IKAELLEDIG LSDVEDIFKE    50
    IPDHLRFDGK LNIPEPKLSE YELKKHVERI LSKNESAQNN LNFKGGGVWQ 100
    HYVPSVCRTI AGRDEFLTAY VGDAYADHGK FQALFETASM IGELVELDAV 150
    NTPTYDWSNA IVRSIRMASR INGRKEVLIP ASMSPSRKKV VLNYCKPDIK 200
    VTEVDFDQDT ALINLDDLQA KLSDQVSSVY IENPNYLGYL EISAQKIGEL 250
    THQHGAEFIV GVDPSSLGVL EAPANYGADM VCGELQPFGL NMKWGGALSG 300
    FIASPDEEKY VGEYPSLLFG ITPTVEEGEY GFGHVAFERT SYAQREKGKD 350
    FIGTSTALYG IVAGVYLALV GPKGLIELGE GIMQRCEYAK KKFAEIEGVS 400
    VPIKTPSFKE FVVDFSGCNK SVKEINQLLE EENIFGGIDL GEKMEEYENC 450
    ALFCFTEVHD RYDINKLINS IEMIIEKY 478
    Length:478
    Mass (Da):53,320
    Last modified:February 8, 2011 - v1
    Checksum:i9D19C691EF533039
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002304 Genomic DNA. Translation: ADQ14239.1.
    RefSeqiWP_013405330.1. NC_014654.1.
    YP_003994593.1. NC_014654.1.

    Genome annotation databases

    EnsemblBacteriaiADQ14239; ADQ14239; Halsa_0792.
    GeneIDi9968382.
    KEGGihas:Halsa_0792.
    PATRICi42640166. VBIHalSp157090_0832.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002304 Genomic DNA. Translation: ADQ14239.1 .
    RefSeqi WP_013405330.1. NC_014654.1.
    YP_003994593.1. NC_014654.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADQ14239 ; ADQ14239 ; Halsa_0792 .
    GeneIDi 9968382.
    KEGGi has:Halsa_0792.
    PATRICi 42640166. VBIHalSp157090_0832.

    Phylogenomic databases

    KOi K00282.

    Enzyme and pathway databases

    BioCyci HHYD656519:GHYV-796-MONOMER.

    Family and domain databases

    Gene3Di 3.40.640.10. 1 hit.
    InterProi IPR020580. GDC-P_N.
    IPR020581. GDC_P.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    [Graphical view ]
    PANTHERi PTHR11773. PTHR11773. 1 hit.
    Pfami PF02347. GDC-P. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53383. SSF53383. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: sapolanicusImported.

    Entry informationi

    Entry nameiE4RN22_HALHG
    AccessioniPrimary (citable) accession number: E4RN22
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 8, 2011
    Last sequence update: February 8, 2011
    Last modified: October 1, 2014
    This is version 24 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3