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E4RKM9 (E4RKM9_HALHG) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 21. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Histidinol-phosphate aminotransferase HAMAP-Rule MF_01023

EC=2.6.1.9 HAMAP-Rule MF_01023
Alternative name(s):
Imidazole acetol-phosphate transaminase HAMAP-Rule MF_01023
Gene names
Name:hisC HAMAP-Rule MF_01023
Ordered Locus Names:Halsa_2268 EMBL ADQ15676.1
OrganismHalanaerobium hydrogeniformans (Halanaerobium sp. (strain sapolanicus)) [Complete proteome] [HAMAP] EMBL ADQ15676.1
Taxonomic identifier656519 [NCBI]
Taxonomic lineageBacteriaFirmicutesClostridiaHalanaerobialesHalanaerobiaceaeHalanaerobium

Protein attributes

Sequence length381 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

L-histidinol phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate. HAMAP-Rule MF_01023 SAAS SAAS005861

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01023 SAAS SAAS005861

Pathway

Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 7/9. HAMAP-Rule MF_01023 SAAS SAAS005861

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_01023

Sequence similarities

Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. HAMAP-Rule MF_01023

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Amino acid modifications

Modified residue2431N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01023

Sequences

Sequence LengthMass (Da)Tools
E4RKM9 [UniParc].

Last modified February 8, 2011. Version 1.
Checksum: 0578C160B94376C8

FASTA38143,799
        10         20         30         40         50         60 
MQIQLESELK KVKKVSNNQK DKEKIIKEML RDEVRSISPY YGEEDDFEVK INLAGNESPF 

        70         80         90        100        110        120 
DLPAKIKDKF INEFQKTDIN RYPEIYSEKI HQELADYLSS ELNKEVSTKE VIIGNGSDEL 

       130        140        150        160        170        180 
LDILIRTFVE KGDIVLSQAP TFSMYRYFSE LGGGIYEEIP LDKDFTIENI KAKIDRLQPK 

       190        200        210        220        230        240 
LIFFCSPNNP TGEILAKDLI LSITEYFSGP VIVDEAYADF SKEDLMAQVE NHANLAVTRT 

       250        260        270        280        290        300 
FSKAFGLAGI RLGYLYGNSV LVEELKKVLK PYNLNTLTDI LGCIVLNNND IIKERIEFIK 

       310        320        330        340        350        360 
KERERVFEHL KSYSDWDLFP SEANFIYLEG KKTHLFKKAL NQAGIKIRSY NTKPAAIRIT 

       370        380 
IGSEEENDAV LRVLEEFKQN N 

« Hide

References

[1]"Complete sequence of Halanaerobium sp. sapolanicus."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., Pitluck S., Davenport K., Detter J.C., Han C., Tapia R., Land M., Hauser L., Jeffries C., Kyrpides N., Ivanova N., Mikhailova N., Begemann M.B. expand/collapse author list , Mormile M.R., Wall J.D., Elias D.A., Woyke T.
Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: sapolanicus.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002304 Genomic DNA. Translation: ADQ15676.1.
RefSeqYP_003996030.1. NC_014654.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADQ15676; ADQ15676; Halsa_2268.
GeneID9969920.
KEGGhas:Halsa_2268.
PATRIC42643340. VBIHalSp157090_2359.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK00817.

Enzyme and pathway databases

BioCycHHYD656519:GHYV-2334-MONOMER.
UniPathwayUPA00031; UER00012.

Family and domain databases

Gene3D3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
HAMAPMF_01023. HisC_aminotrans_2.
InterProIPR001917. Aminotrans_II_pyridoxalP_BS.
IPR004839. Aminotransferase_I/II.
IPR005861. HisP_aminotrans.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PfamPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
SUPFAMSSF53383. SSF53383. 1 hit.
TIGRFAMsTIGR01141. hisC. 1 hit.
PROSITEPS00599. AA_TRANSFER_CLASS_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameE4RKM9_HALHG
AccessionPrimary (citable) accession number: E4RKM9
Entry history
Integrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: July 9, 2014
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)