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E4RHW3

- E4RHW3_PSEPB

UniProt

E4RHW3 - E4RHW3_PSEPB

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Protein
Alanine racemase
Gene
alr, PPUBIRD1_2040
Organism
Pseudomonas putida (strain BIRD-1)
Status
Unreviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotations

Cofactori

Pyridoxal phosphate By similarity.UniRule annotationSAAS annotations

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei46 – 461Proton acceptor; specific for D-alanine By similarityUniRule annotation
Binding sitei145 – 1451Substrate By similarityUniRule annotation
Active sitei272 – 2721Proton acceptor; specific for L-alanine By similarityUniRule annotation
Binding sitei320 – 3201Substrate; via amide nitrogen By similarityUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotationsImported

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciPPUT931281:GLIU-2024-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Name:alrImported
Ordered Locus Names:PPUBIRD1_2040Imported
OrganismiPseudomonas putida (strain BIRD-1)Imported
Taxonomic identifieri931281 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000008715: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei46 – 461N6-(pyridoxal phosphate)lysine By similarityUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliE4RHW3.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK01775.
OMAiQQIPCVA.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E4RHW3-1 [UniParc]FASTAAdd to Basket

« Hide

MDNGTNTLTV QNSNAWVEVS ASALQHNIRT LQAELAGKSK LCAVLKADAY    50
GHGIGLVMPS IIAQGVPCVA VASNEEARVV RASGFTGQLV RVRLASLSEL 100
EDGLQYDMEE LVGSAEFARQ ADAIAARHGK TLRIHMALNS SGMSRNGVEM 150
ATWSGRGEAL QITDQKHLKL VALMTHFAVE DKDDVRKGLA AFNEQTDWLI 200
KHAKLDRSKL TLHAANSFAT LEVPEARLDM VRTGGALFGD TVPGRTEYKR 250
AMQFKSHVAA VHSYPAGNTV GYDRTFTLAR DSRLANITVG YSDGYRRVFT 300
NKGHVLINGH RVPVVGKVSM NTLMVDVTDF PDVKGGNEVV LFGKQAGGEI 350
TQAEMEEING ALLADLYTVW GSSNPKMLVD 380
Length:380
Mass (Da):41,138
Last modified:February 8, 2011 - v1
Checksum:i48DE849B2DD04559
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002290 Genomic DNA. Translation: ADR59688.1.
RefSeqiWP_014590554.1. NC_017530.1.
YP_005929893.1. NC_017530.1.

Genome annotation databases

EnsemblBacteriaiADR59688; ADR59688; PPUBIRD1_2040.
GeneIDi12520257.
KEGGippb:PPUBIRD1_2040.
PATRICi45406028. VBIPsePut176522_2057.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002290 Genomic DNA. Translation: ADR59688.1 .
RefSeqi WP_014590554.1. NC_017530.1.
YP_005929893.1. NC_017530.1.

3D structure databases

ProteinModelPortali E4RHW3.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADR59688 ; ADR59688 ; PPUBIRD1_2040 .
GeneIDi 12520257.
KEGGi ppb:PPUBIRD1_2040.
PATRICi 45406028. VBIPsePut176522_2057.

Phylogenomic databases

KOi K01775.
OMAi QQIPCVA.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci PPUT931281:GLIU-2024-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Complete genome of the plant-growth promoting rhizobacteria Pseudomonas putida BIRD-1."
    Matilla M.A., Pizarro P., Roca A., Fernandez M., Duque E., Molina L., van der Lelie D., Gomez M.J., Ramos J.-L.
    Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BIRD-1.
  2. "Complete genome of the plant growth-promoting rhizobacterium Pseudomonas putida BIRD-1."
    Matilla M.A., Pizarro-Tobias P., Roca A., Fernandez M., Duque E., Molina L., Wu X., van der Lelie D., Gomez M.J., Segura A., Ramos J.L.
    J. Bacteriol. 193:1290-1290(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BIRD-1Imported.

Entry informationi

Entry nameiE4RHW3_PSEPB
AccessioniPrimary (citable) accession number: E4RHW3
Entry historyi
Integrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: September 3, 2014
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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