E4RFE4 (E4RFE4_PSEPB) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
2-dehydropantoate 2-reductase RuleBase RU003776
EC=1.1.1.169 RuleBase RU003776

Gene names

Ordered Locus Names:

PPUBIRD1_2689

Organism

Pseudomonas putida (strain BIRD-1) [Complete proteome] [HAMAP] EMBL ADR60312.1

Taxonomic identifier

931281 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas › Pseudomonas putida group › Pseudomonas putida

Protein attributes

Sequence length	315 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid By similarity. RuleBase RU003776
Catalytic activity	(R)-pantoate + NADP+ = 2-dehydropantoate + NADPH. RuleBase RU003776
Pathway	Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantoate from 3-methyl-2-oxobutanoate: step 2/2. RuleBase RU004251
Sequence similarities	Belongs to the ketopantoate reductase family. RuleBase RU003776

Ontologies

Keywords
Biological process	Pantothenate biosynthesis RuleBase RU003776
Ligand	NADP RuleBase RU003776
Molecular function	Oxidoreductase RuleBase RU003776
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	pantothenate biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Cellular_component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular_function	2-dehydropantoate 2-reductase activity Inferred from electronic annotation. Source: EC NADP binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	E4RFE4 [UniParc]. Last modified February 8, 2011. Version 1. Checksum: 54C87A3AD3C149E6	FASTA	315	32,831
	10 20 30 40 50 60 MKICILGAGA LGCAIGAALS EAGHETWLLN RGRAHVEAMN QHGLRVQDER GERYVPVNAA 70 80 90 100 110 120 IEAEDVGVTD LVVVLVKSFH TAEAIAGALA LIGPQTLVLS LQNGLGHEDI LAEVVGRERV 130 140 150 160 170 180 LAGKTYVGGV LLAPGSIRAG VAGKQTFIGE LDGQLTPRAQ AIAEAFNNAG LATTVSDNIL 190 200 210 220 230 240 GTMWDKLLVN VATGALSGIT MLSYGQLYSE PLLESTAKAA VAEAIAVAER AGIRLSLTSP 250 260 270 280 290 300 EAAWSLAAEG LPASFRTSML QSLEKNSITE IDFINGSVVR WGQRHGVATP VNATLVACIK 310 GIERAMADHQ KGETP

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete genome of the plant-growth promoting rhizobacteria Pseudomonas putida BIRD-1." Matilla M.A., Pizarro P., Roca A., Fernandez M., Duque E., Molina L., van der Lelie D., Gomez M.J., Ramos J.-L. Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: BIRD-1.
[2]	"Complete genome of the plant growth-promoting rhizobacterium Pseudomonas putida BIRD-1." Matilla M.A., Pizarro-Tobias P., Roca A., Fernandez M., Duque E., Molina L., Wu X., van der Lelie D., Gomez M.J., Segura A., Ramos J.L. J. Bacteriol. 193:1290-1290(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: BIRD-1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002290 Genomic DNA. Translation: ADR60312.1.
RefSeq	YP_005930517.1. NC_017530.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADR60312; ADR60312; PPUBIRD1_2689.
GeneID	12520881.
KEGG	ppb:PPUBIRD1_2689.
PATRIC	45407337. VBIPsePut176522_2707.
Organism-specific databases
CMR	Search...
Phylogenomic databases
KO	K00077.
Enzyme and pathway databases
UniPathway	UPA00028; UER00004.
Family and domain databases
Gene3D	1.10.1040.10. 1 hit. 3.40.50.720. 1 hit.
InterPro	IPR008927. 6-PGluconate_DH_C-like. IPR003710. ApbA. IPR013752. ApbA_C. IPR013332. ApbA_N. IPR013328. DH_multihelical. IPR016040. NAD(P)-bd_dom. [Graphical view]
Pfam	PF02558. ApbA. 1 hit. PF08546. ApbA_C. 1 hit. [Graphical view]
SUPFAM	SSF48179. 6DGDH_C_like. 1 hit.
TIGRFAMs	TIGR00745. apbA_panE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

E4RFE4_PSEPB

Accession

Primary (citable) accession number: E4RFE4

Entry history

Integrated into UniProtKB/TrEMBL:	February 8, 2011
Last sequence update:	February 8, 2011
Last modified:	May 1, 2013
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)