Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

E4QUT5 (E4QUT5_HAEI6) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Phosphoenolpyruvate carboxylase HAMAP-Rule MF_00595

Short name=PEPC HAMAP-Rule MF_00595
Short name=PEPCase HAMAP-Rule MF_00595
EC=4.1.1.31 HAMAP-Rule MF_00595
Gene names
Name:ppc HAMAP-Rule MF_00595 EMBL ADO81113.1
Ordered Locus Names:R2866_1175 EMBL ADO81113.1
OrganismHaemophilus influenzae (strain R2866) [Complete proteome] [HAMAP] EMBL ADO81113.1
Taxonomic identifier262728 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus

Protein attributes

Sequence length879 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. HAMAP-Rule MF_00595 SAAS SAAS021135

Catalytic activity

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP-Rule MF_00595 SAAS SAAS018129

Cofactor

Magnesium By similarity. HAMAP-Rule MF_00595 SAAS SAAS018129

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00595

Sequence similarities

Belongs to the PEPCase type 1 family. HAMAP-Rule MF_00595

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1381 By similarity HAMAP-Rule MF_00595
Active site5451 By similarity HAMAP-Rule MF_00595

Sequences

Sequence LengthMass (Da)Tools
E4QUT5 [UniParc].

Last modified February 8, 2011. Version 1.
Checksum: 3E5388F2E2AA7C40

FASTA879100,069
        10         20         30         40         50         60 
MTQEYSTLRN NISMLGRFLG ETINDAQGED ILELIENIRK LSRNSRAGDD KARQALLDTL 

        70         80         90        100        110        120 
GSISNENIIP VARAFSQFLN LTNIAEQYQT ISREHSLAQS SSQSLSELFK RLKEQNASVE 

       130        140        150        160        170        180 
EVHKTVEKLL IELVLTAHPT ETTRRSLIHK HIEINKCLSK LEHHDLTEKE RNIIERLLLR 

       190        200        210        220        230        240 
LIAEAWHTNE IRTVRPTPFD EAKWGFAMLE NSLWQAVPEF LRQLNETARE FLGYDLSVGL 

       250        260        270        280        290        300 
KPVRISSWMG GDRDGNPFVT AQITKKVLYF ARWKAADLFL QDISKLADEL SMMKCSDEFR 

       310        320        330        340        350        360 
DKYGEHLEPY RFVVKNLRNQ LTATLAYFDD HLSNRTPRVS ESEIILEDNQ LWEPLYDCYQ 

       370        380        390        400        410        420 
SLIQCGMRII ANGSLLNILH RISCFGVTLS QMDIRQESTR HTDAIAEITR YIGLGDYSQW 

       430        440        450        460        470        480 
MEDDKQAFLI RELSSRRPLI PQNWTPSPET KEILDTCKVI AQQKQGVIAC YVISMARSAS 

       490        500        510        520        530        540 
DVLAVHLLLK ESGVPYHIPV VPLFETLEDL DAAEKVMTQL FNVGWYRGVI NNRQMVMIGY 

       550        560        570        580        590        600 
SDSAKDAGMM AASWAQYRAQ EALVNLTEKL GIELTLFHGR GGTIGRGGAP AHAALLSQPP 

       610        620        630        640        650        660 
RSLKNGLRVT EQGEMIRFKL GLPAVAVETF DLYASAILEA NLLPPPEPKP EWRTIMDELS 

       670        680        690        700        710        720 
TISCDIYRGV VRGDKDFVPY FRSATPEQEL SKLPLGSRPA KRNPNGGVES LRAIPWIFAW 

       730        740        750        760        770        780 
MQNRLMLPAW LGAGAAIRQI IEQGKGDIIH KMCENWPFFS TRIGMLEMVF SKSDTWLSQQ 

       790        800        810        820        830        840 
YDQRLVKKEL WYLGENLRKQ LEDDIQTVLS LSHQSELMSD LPWIADSIAL RNIYTDPLNL 

       850        860        870 
LQVELLHRFR ENPEQVNPDV EQALMITITG IAAGMRNTG 

« Hide

References

[1]"Genome sequence of the invasive non-typeable isolate Haemophilus influenzae R2866."
VanWagoner T.M., Erwin A.L., Kaul R., Mahaffey M., Zhou Y., Aggarwal G., Chang J., Deng H., Gillett W., Haugen E., Kibukawa M., Phelps K., Saenphimmachak C., Sivam D., Worthey E.A., Olson M.V., Stull T.L., Smith A.L.
Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: R2866 EMBL ADO81113.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002277 Genomic DNA. Translation: ADO81113.1.
RefSeqYP_005827844.1. NC_017451.1.

3D structure databases

ProteinModelPortalE4QUT5.
SMRE4QUT5. Positions 4-879.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADO81113; ADO81113; R2866_1175.
GeneID12595960.
KEGGhiz:R2866_1175.
PATRIC43047540. VBIHaeInf103652_1188.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01595.
OMAELSTISC.

Enzyme and pathway databases

BioCycHINF262728:GLDR-1175-MONOMER.

Family and domain databases

HAMAPMF_00595. PEPcase_type1.
InterProIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSPR00150. PEPCARBXLASE.
SUPFAMSSF51621. SSF51621. 1 hit.
PROSITEPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameE4QUT5_HAEI6
AccessionPrimary (citable) accession number: E4QUT5
Entry history
Integrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: June 11, 2014
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)