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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Methylovorus sp. (strain MP688)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei152 – 1521UniRule annotation
Active sitei590 – 5901UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciMSP887061:GHJT-1509-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
Ordered Locus Names:MPQ_1509Imported
OrganismiMethylovorus sp. (strain MP688)Imported
Taxonomic identifieri887061 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaMethylophilalesMethylophilaceaeMethylovorus
ProteomesiUP000007036: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E4QQD6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVIGEHGMTS RIYSHNEKLL RENIRYLGRV LGEVIKSKEG EETFDRIEAI
60 70 80 90 100
RTAAVNFHRH GNTKAAKSLE KLLKTLTVEQ AIPVIRAFSY FKHLVNIAED
110 120 130 140 150
LHAHQQSRLV EDQAVPGMLT HSLQKLAASD LDAAEIGDFF ANALISPVLT
160 170 180 190 200
AHPTEVQRKS ILDTERALSL LLVEKSNVVS IREAERNERM IVGAITTLWQ
210 220 230 240 250
TRILRFSKLT VANEIENALS YYRMTFLQVI PELMQDFEND LRHVFADKLS
260 270 280 290 300
PEYKLPSFLQ MGSWIGGDRD GNPFVNGATL EQAIIQQSAT AFAYYLEQVE
310 320 330 340 350
ALRSELSLST RLVGVTPALV KLAEASGEQS LHRQDETYRL ALNGIHARLA
360 370 380 390 400
QTAKLLVNER GDVRREISAI PYTSAEALLA DMNVIAESLQ SQQGEALIYP
410 420 430 440 450
RLGKLIKAIE TFGFHLATVD LRQSSDVHEL VIKELFLKAG QDFNYATLDE
460 470 480 490 500
DEKVEVLLEE LKQPRLLFSP FQQYSELVQS EMEVLQKARG IRAGYGKRAI
510 520 530 540 550
RQYIISHTET LSDLLEVALL QKETGMLRGV WGSAKVQMDL NIVPLFETIA
560 570 580 590 600
DLRHAPMIMG QWLSLLGIRH LLRYQGNEQE IMLGYSDSNK DGGFITSNWE
610 620 630 640 650
LYKAEISLVE LFRQANIRLR LFHGRGGTVG RGGGPTYQAI MAQPQGTVDG
660 670 680 690 700
QIRLTEQGEI IANKYSEPRV GRQHLETLVA ATIDGSLFPP DPLLAKKRRS
710 720 730 740 750
FEIIMEELSA TAMTAYRTLV YETAGFAEYF FNATPISEIA ELNIGSRPAS
760 770 780 790 800
RKATQRIEDL RAIPWGFSWG QCRLLLPGWF GVGSAIHEYL FIEDKLQPAR
810 820 830 840 850
LKTLHDMLEQ WPLFRSLISN VDMVLAKTDL AVAQRYSMLV PDKKLREGIF
860 870 880 890 900
AAIEHEYQLT TEALNLLLNS TERLSSNPAL ANSIQNRLPY LDPLNHLQVE
910 920 930
LIRQYRQGAT NDRVKLAIHL TINGIAAGLR NTG
Length:933
Mass (Da):104,987
Last modified:February 8, 2011 - v1
Checksum:i2786BF95F10BDB2C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002252 Genomic DNA. Translation: ADQ84667.1.
RefSeqiWP_013442290.1. NC_014733.1.
YP_004039903.1. NC_014733.1.

Genome annotation databases

EnsemblBacteriaiADQ84667; ADQ84667; MPQ_1509.
GeneIDi9996347.
KEGGimep:MPQ_1509.
PATRICi45265273. VBIMetSp170262_1461.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002252 Genomic DNA. Translation: ADQ84667.1.
RefSeqiWP_013442290.1. NC_014733.1.
YP_004039903.1. NC_014733.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADQ84667; ADQ84667; MPQ_1509.
GeneIDi9996347.
KEGGimep:MPQ_1509.
PATRICi45265273. VBIMetSp170262_1461.

Phylogenomic databases

HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.

Enzyme and pathway databases

BioCyciMSP887061:GHJT-1509-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Complete genome sequence of the PQQ high-production bacteria Methylovorus sp. MP688."
    Xiong X., Wang J., Zhang W., Yang L., Zhi J., Wang X., Cui Y., Dong F., Li M., Yang Y., Du B.
    Submitted (SEP-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MP688.
  2. "Complete genome sequence of the bacterium Methylovorus sp. strain MP688, a high-level producer of pyrroloquinolone quinone."
    Xiong X.H., Zhi J.J., Yang L., Wang J.H., Zhao Y., Wang X., Cui Y.J., Dong F., Li M.X., Yang Y.X., Wei N., An J.J., Du B.H., Liang L., Zhang J.S., Zhou W., Cheng S.F., He T.
    , Wang L., Chen H.P., Liu D.S., Zhang W.C.
    J. Bacteriol. 193:1012-1013(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MP688Imported.

Entry informationi

Entry nameiE4QQD6_METS6
AccessioniPrimary (citable) accession number: E4QQD6
Entry historyi
Integrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: March 4, 2015
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.