ID   E4QD31_CALH1            Unreviewed;       393 AA.
AC   E4QD31;
DT   08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT   08-FEB-2011, sequence version 1.
DT   27-MAR-2024, entry version 54.
DE   SubName: Full=Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein {ECO:0000313|EMBL:ADQ07525.1};
GN   OrderedLocusNames=Calhy_1814 {ECO:0000313|EMBL:ADQ07525.1};
OS   Caldicellulosiruptor hydrothermalis (strain DSM 18901 / VKM B-2411 / 108).
OC   Bacteria; Bacillota; Clostridia; Caldicellulosiruptorales;
OC   Caldicellulosiruptoraceae; Caldicellulosiruptor.
OX   NCBI_TaxID=632292 {ECO:0000313|EMBL:ADQ07525.1, ECO:0000313|Proteomes:UP000006890};
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=108;
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA   Pitluck S., Davenport K., Detter J.C., Han C., Tapia R., Land M.,
RA   Hauser L., Chang Y.-J., Jeffries C., Kyrpides N., Ivanova N.,
RA   Mikhailova N., Blumer-Schuette S.E., Kelly R.M., Woyke T.;
RT   "Complete sequence of Caldicellulosiruptor hydrothermalis 108.";
RL   Submitted (SEP-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ADQ07525.1, ECO:0000313|Proteomes:UP000006890}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 18901 / VKM B-2411 / 108
RC   {ECO:0000313|Proteomes:UP000006890};
RX   PubMed=21216991; DOI=10.1128/JB.01515-10;
RA   Blumer-Schuette S.E., Ozdemir I., Mistry D., Lucas S., Lapidus A.,
RA   Cheng J.F., Goodwin L.A., Pitluck S., Land M.L., Hauser L.J., Woyke T.,
RA   Mikhailova N., Pati A., Kyrpides N.C., Ivanova N., Detter J.C.,
RA   Walston-Davenport K., Han S., Adams M.W., Kelly R.M.;
RT   "Complete genome sequences for the anaerobic, extremely thermophilic plant
RT   biomass-degrading bacteria Caldicellulosiruptor hydrothermalis,
RT   Caldicellulosiruptor kristjanssonii, Caldicellulosiruptor kronotskyensis,
RT   Caldicellulosiruptor owensenis, and Caldicellulosiruptor lactoaceticus.";
RL   J. Bacteriol. 193:1483-1484(2011).
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DR   EMBL; CP002219; ADQ07525.1; -; Genomic_DNA.
DR   RefSeq; WP_013403680.1; NC_014652.1.
DR   AlphaFoldDB; E4QD31; -.
DR   STRING; 632292.Calhy_1814; -.
DR   KEGG; chd:Calhy_1814; -.
DR   eggNOG; COG0674; Bacteria.
DR   HOGENOM; CLU_002569_5_0_9; -.
DR   OrthoDB; 9794954at2; -.
DR   Proteomes; UP000006890; Chromosome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   CDD; cd07034; TPP_PYR_PFOR_IOR-alpha_like; 1.
DR   Gene3D; 3.40.50.920; -; 1.
DR   Gene3D; 3.40.50.970; -; 1.
DR   InterPro; IPR033412; PFOR_II.
DR   InterPro; IPR002880; Pyrv_Fd/Flavodoxin_OxRdtase_N.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR009014; Transketo_C/PFOR_II.
DR   PANTHER; PTHR32154; PYRUVATE-FLAVODOXIN OXIDOREDUCTASE-RELATED; 1.
DR   PANTHER; PTHR32154:SF0; PYRUVATE-FLAVODOXIN OXIDOREDUCTASE-RELATED; 1.
DR   Pfam; PF17147; PFOR_II; 1.
DR   Pfam; PF01855; POR_N; 1.
DR   SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR   SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE   4: Predicted;
KW   Pyruvate {ECO:0000313|EMBL:ADQ07525.1}.
FT   DOMAIN          16..240
FT                   /note="Pyruvate flavodoxin/ferredoxin oxidoreductase
FT                   pyrimidine binding"
FT                   /evidence="ECO:0000259|Pfam:PF01855"
FT   DOMAIN          262..366
FT                   /note="Pyruvate:ferredoxin oxidoreductase core"
FT                   /evidence="ECO:0000259|Pfam:PF17147"
SQ   SEQUENCE   393 AA;  43280 MW;  A9887979D947D8AD CRC64;
     MAIRDRLSGN EAVAFAMKQI NPDVVAAFPI TPSTEVPQYF SQYVANGEVD TEFVAVESEH
     SAMSACIGAS AAGARTMTAT SSQGLALMWE MLYIAASMRL PIVMAVINRA LSGPINIHND
     HSDSMGARDS GWIQIYCENN QEAYDSLIQA IRIAEHKDVR LPVMVCYDGF ITSHAVENIE
     LLEDELVKKF VGEYNPEFYL LNEQNPISMG PLDLPPYYFE HKRQQAEAMK NAKKVVLEVA
     EEFAALTGRK YGLFEAYKLD DAEVAIVVMN STAGTAKAVV DEYRSKGYKV GLLKPRLFRP
     FPVDEIVGAL KHLKAVAIMD KSDGFNAAGG PLFTEITSAL YGRAEGIKAI NYIYGLGGRD
     VKTDDIAKVY DRLLDIVKTG NVGEVYNYIG VRE
//