ID   E4QCZ7_CALH1            Unreviewed;       479 AA.
AC   E4QCZ7;
DT   08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT   08-FEB-2011, sequence version 1.
DT   27-MAR-2024, entry version 52.
DE   SubName: Full=FAD dependent oxidoreductase {ECO:0000313|EMBL:ADQ07491.1};
GN   OrderedLocusNames=Calhy_1776 {ECO:0000313|EMBL:ADQ07491.1};
OS   Caldicellulosiruptor hydrothermalis (strain DSM 18901 / VKM B-2411 / 108).
OC   Bacteria; Bacillota; Clostridia; Caldicellulosiruptorales;
OC   Caldicellulosiruptoraceae; Caldicellulosiruptor.
OX   NCBI_TaxID=632292 {ECO:0000313|EMBL:ADQ07491.1, ECO:0000313|Proteomes:UP000006890};
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=108;
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA   Pitluck S., Davenport K., Detter J.C., Han C., Tapia R., Land M.,
RA   Hauser L., Chang Y.-J., Jeffries C., Kyrpides N., Ivanova N.,
RA   Mikhailova N., Blumer-Schuette S.E., Kelly R.M., Woyke T.;
RT   "Complete sequence of Caldicellulosiruptor hydrothermalis 108.";
RL   Submitted (SEP-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ADQ07491.1, ECO:0000313|Proteomes:UP000006890}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 18901 / VKM B-2411 / 108
RC   {ECO:0000313|Proteomes:UP000006890};
RX   PubMed=21216991; DOI=10.1128/JB.01515-10;
RA   Blumer-Schuette S.E., Ozdemir I., Mistry D., Lucas S., Lapidus A.,
RA   Cheng J.F., Goodwin L.A., Pitluck S., Land M.L., Hauser L.J., Woyke T.,
RA   Mikhailova N., Pati A., Kyrpides N.C., Ivanova N., Detter J.C.,
RA   Walston-Davenport K., Han S., Adams M.W., Kelly R.M.;
RT   "Complete genome sequences for the anaerobic, extremely thermophilic plant
RT   biomass-degrading bacteria Caldicellulosiruptor hydrothermalis,
RT   Caldicellulosiruptor kristjanssonii, Caldicellulosiruptor kronotskyensis,
RT   Caldicellulosiruptor owensenis, and Caldicellulosiruptor lactoaceticus.";
RL   J. Bacteriol. 193:1483-1484(2011).
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DR   EMBL; CP002219; ADQ07491.1; -; Genomic_DNA.
DR   RefSeq; WP_013403647.1; NC_014652.1.
DR   AlphaFoldDB; E4QCZ7; -.
DR   STRING; 632292.Calhy_1776; -.
DR   KEGG; chd:Calhy_1776; -.
DR   eggNOG; COG0579; Bacteria.
DR   eggNOG; COG1251; Bacteria.
DR   HOGENOM; CLU_024775_3_1_9; -.
DR   OrthoDB; 9801699at2; -.
DR   Proteomes; UP000006890; Chromosome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   CDD; cd19946; GlpA-like_Fer2_BFD-like; 1.
DR   Gene3D; 1.10.10.1100; BFD-like [2Fe-2S]-binding domain; 1.
DR   Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR007419; BFD-like_2Fe2S-bd_dom.
DR   InterPro; IPR041854; BFD-like_2Fe2S-bd_dom_sf.
DR   InterPro; IPR006076; FAD-dep_OxRdtase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   PANTHER; PTHR42720:SF1; GLYCEROL 3-PHOSPHATE OXIDASE; 1.
DR   PANTHER; PTHR42720; GLYCEROL-3-PHOSPHATE DEHYDROGENASE; 1.
DR   Pfam; PF01266; DAO; 1.
DR   Pfam; PF04324; Fer2_BFD; 1.
DR   SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE   4: Predicted;
FT   DOMAIN          6..357
FT                   /note="FAD dependent oxidoreductase"
FT                   /evidence="ECO:0000259|Pfam:PF01266"
FT   DOMAIN          401..452
FT                   /note="BFD-like [2Fe-2S]-binding"
FT                   /evidence="ECO:0000259|Pfam:PF04324"
SQ   SEQUENCE   479 AA;  53785 MW;  0725A8EEA9F02DC9 CRC64;
     MSRIYDVAVI GAGVVGMSIL RELTRYRLKV CSLEKMEDVA EGASKANSGI VHAGYDPIEG
     TKKARFNVEG NNIFADICNE LDVEYKMIGS LVVAFDDYEI NVLEELLQRG KRNGVKGLEI
     KSQEWVFENE PNLSRNIKAA LFAPYSGITN PYKLTVALFE NAIQNGADVI FSFEVCKIEK
     DGDYFVVHSA DSRFVKTKVL INCAGVHADE ISKMAGARLF KIYPRRGQYY ILDKPQKMPV
     ARVIFQVPTE KGKGILVTPT VDGNVLVGPN SEYIDSKDDT ATTQEGLDEV FEKARKVLPS
     LSKRDVITIF SGIRATPDTH DFIIEEDEDV KNFINVAGIE SPGLTASLAI GKYIAELVSD
     KLNAKRNLNF NPYRKDIKRF SELSDEEREE MIKLHPSFGN IVCRCELVSE YEIVEAIKRG
     AKTLDSIKRR IRAGMGRCQG GFCLPRVMDI LSRELKIDKT QITKFGKNSY ILTEKRWED
//