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E4PTH5

- E4PTH5_MYCLG

UniProt

E4PTH5 - E4PTH5_MYCLG

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Protein

Elongation factor Tu

Gene

tuf

Organism
Mycoplasma leachii (strain DSM 21131 / NCTC 10133 / N29 / PG50)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi19 – 268GTPUniRule annotation
Nucleotide bindingi81 – 855GTPUniRule annotation
Nucleotide bindingi136 – 1394GTPUniRule annotation

GO - Molecular functioni

  1. GTPase activity Source: InterPro
  2. GTP binding Source: UniProtKB-HAMAP
  3. translation elongation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Elongation factorUniRule annotation, HydrolaseImported

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciMLEA880447:GC0N-202-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TuUniRule annotation
Short name:
EF-TuUniRule annotation
Gene namesi
Name:tufUniRule annotationImported
Ordered Locus Names:MSB_A0204Imported
OrganismiMycoplasma leachii (strain DSM 21131 / NCTC 10133 / N29 / PG50)Imported
Taxonomic identifieri880447 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
ProteomesiUP000008712: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

PTM / Processingi

Proteomic databases

PRIDEiE4PTH5.

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliE4PTH5.
SMRiE4PTH5. Positions 2-393.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000229290.
KOiK02358.
OMAiGTEMCMP.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B.
InterProiIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. EFACTOR_GTP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E4PTH5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAKEQFDRSL PHVNIGTIGH VDHGKTTLTA AITKVLSEQG NAEFKDYANI
60 70 80 90 100
DNAPEERERG ITINTAHVEY KTANRHYAHV DCPGHADYVK NMITGAAQMD
110 120 130 140 150
GAILVVAATD GPMPQTREHI LLSRQVGVPK IVVFLNKCDM VEDDEMIDLV
160 170 180 190 200
EMEIRDLLTE YDFDGEGAPV IRGSALGALN GDSKWTGAIN ELMAAVDEYI
210 220 230 240 250
PTPQRDADKT FLMPVEDVFT ITGRGTVATG RVERGTVKVN EEVEIIGLKE
260 270 280 290 300
EPTKTVVTGL EMFRKLLDFA VAGDNVGALL RGVDRHSVER GQVLAKPGTI
310 320 330 340 350
KPHTVLKASV YALTQEEGGR HKPFFNKYRP QFYFRTTDVT GEVTLPEGTD
360 370 380 390
MVMPGDNVEM EIQLIKPVAV EEGTKFSIRE GGRTIGAGTV ISIEK
Length:395
Mass (Da):43,304
Last modified:February 8, 2011 - v1
Checksum:i908B9E1844E6070E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002108 Genomic DNA. Translation: ADR23857.1.
RefSeqiYP_004046961.1. NC_014751.1.

Genome annotation databases

EnsemblBacteriaiADR23857; ADR23857; MSB_A0204.
GeneIDi10004655.
KEGGimlc:MSB_A0204.
PATRICi45296280. VBIMycLea173401_0201.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002108 Genomic DNA. Translation: ADR23857.1 .
RefSeqi YP_004046961.1. NC_014751.1.

3D structure databases

ProteinModelPortali E4PTH5.
SMRi E4PTH5. Positions 2-393.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi E4PTH5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADR23857 ; ADR23857 ; MSB_A0204 .
GeneIDi 10004655.
KEGGi mlc:MSB_A0204.
PATRICi 45296280. VBIMycLea173401_0201.

Phylogenomic databases

HOGENOMi HOG000229290.
KOi K02358.
OMAi GTEMCMP.

Enzyme and pathway databases

BioCyci MLEA880447:GC0N-202-MONOMER.

Family and domain databases

Gene3Di 3.40.50.300. 1 hit.
HAMAPi MF_00118_B. EF_Tu_B.
InterProi IPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view ]
Pfami PF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view ]
PRINTSi PR00315. ELONGATNFCT.
SUPFAMi SSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEi PS00301. EFACTOR_GTP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of Mycoplasma leachii PG50 MU clone A8."
    Wise K., Calcutt M.J., Foecking M.F., Madupu R., DeBoy R.T., Roske K., Martin T.R., Hvinden M.L., Durkin A.S., Glass J., Methe B.A.
    Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 21131 / NCTC 10133 / N29 / PG50Imported.

Entry informationi

Entry nameiE4PTH5_MYCLG
AccessioniPrimary (citable) accession number: E4PTH5
Entry historyi
Integrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: October 29, 2014
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3