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E4PTH5

- E4PTH5_MYCLG

UniProt

E4PTH5 - E4PTH5_MYCLG

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Protein
Elongation factor Tu
Gene
tuf, MSB_A0204
Organism
Mycoplasma leachii (strain DSM 21131 / NCTC 10133 / N29 / PG50)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi19 – 268GTP By similarityUniRule annotation
Nucleotide bindingi81 – 855GTP By similarityUniRule annotation
Nucleotide bindingi136 – 1394GTP By similarityUniRule annotation

GO - Molecular functioni

  1. GTP binding Source: UniProtKB-HAMAP
  2. GTPase activity Source: InterPro
  3. translation elongation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    Elongation factorUniRule annotationImported, HydrolaseImported

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    GTP-bindingUniRule annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciMLEA880447:GC0N-202-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Elongation factor TuUniRule annotation
    Short name:
    EF-TuUniRule annotation
    Gene namesi
    Name:tufUniRule annotationImported
    Ordered Locus Names:MSB_A0204Imported
    OrganismiMycoplasma leachii (strain DSM 21131 / NCTC 10133 / N29 / PG50)Imported
    Taxonomic identifieri880447 [NCBI]
    Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
    ProteomesiUP000008712: Chromosome

    Subcellular locationi

    Cytoplasm By similarity UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    Complete GO annotation...

    Keywords - Cellular componenti

    CytoplasmUniRule annotation

    PTM / Processingi

    Proteomic databases

    PRIDEiE4PTH5.

    Interactioni

    Subunit structurei

    Monomer By similarity.UniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliE4PTH5.
    SMRiE4PTH5. Positions 2-393.

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    HOGENOMiHOG000229290.
    KOiK02358.
    OMAiGTEMCMP.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    HAMAPiMF_00118_B. EF_Tu_B.
    InterProiIPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view]
    PfamiPF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view]
    PRINTSiPR00315. ELONGATNFCT.
    SUPFAMiSSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEiPS00301. EFACTOR_GTP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E4PTH5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAKEQFDRSL PHVNIGTIGH VDHGKTTLTA AITKVLSEQG NAEFKDYANI    50
    DNAPEERERG ITINTAHVEY KTANRHYAHV DCPGHADYVK NMITGAAQMD 100
    GAILVVAATD GPMPQTREHI LLSRQVGVPK IVVFLNKCDM VEDDEMIDLV 150
    EMEIRDLLTE YDFDGEGAPV IRGSALGALN GDSKWTGAIN ELMAAVDEYI 200
    PTPQRDADKT FLMPVEDVFT ITGRGTVATG RVERGTVKVN EEVEIIGLKE 250
    EPTKTVVTGL EMFRKLLDFA VAGDNVGALL RGVDRHSVER GQVLAKPGTI 300
    KPHTVLKASV YALTQEEGGR HKPFFNKYRP QFYFRTTDVT GEVTLPEGTD 350
    MVMPGDNVEM EIQLIKPVAV EEGTKFSIRE GGRTIGAGTV ISIEK 395
    Length:395
    Mass (Da):43,304
    Last modified:February 8, 2011 - v1
    Checksum:i908B9E1844E6070E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002108 Genomic DNA. Translation: ADR23857.1.
    RefSeqiYP_004046961.1. NC_014751.1.

    Genome annotation databases

    EnsemblBacteriaiADR23857; ADR23857; MSB_A0204.
    GeneIDi10004655.
    KEGGimlc:MSB_A0204.
    PATRICi45296280. VBIMycLea173401_0201.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002108 Genomic DNA. Translation: ADR23857.1 .
    RefSeqi YP_004046961.1. NC_014751.1.

    3D structure databases

    ProteinModelPortali E4PTH5.
    SMRi E4PTH5. Positions 2-393.
    ModBasei Search...

    Proteomic databases

    PRIDEi E4PTH5.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADR23857 ; ADR23857 ; MSB_A0204 .
    GeneIDi 10004655.
    KEGGi mlc:MSB_A0204.
    PATRICi 45296280. VBIMycLea173401_0201.

    Phylogenomic databases

    HOGENOMi HOG000229290.
    KOi K02358.
    OMAi GTEMCMP.

    Enzyme and pathway databases

    BioCyci MLEA880447:GC0N-202-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    HAMAPi MF_00118_B. EF_Tu_B.
    InterProi IPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view ]
    Pfami PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view ]
    PRINTSi PR00315. ELONGATNFCT.
    SUPFAMi SSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEi PS00301. EFACTOR_GTP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of Mycoplasma leachii PG50 MU clone A8."
      Wise K., Calcutt M.J., Foecking M.F., Madupu R., DeBoy R.T., Roske K., Martin T.R., Hvinden M.L., Durkin A.S., Glass J., Methe B.A.
      Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DSM 21131 / NCTC 10133 / N29 / PG50.

    Entry informationi

    Entry nameiE4PTH5_MYCLG
    AccessioniPrimary (citable) accession number: E4PTH5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 8, 2011
    Last sequence update: February 8, 2011
    Last modified: June 11, 2014
    This is version 24 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    External Data

    Dasty 3

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