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E4PAA5

- E4PAA5_ECO8N

UniProt

E4PAA5 - E4PAA5_ECO8N

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Protein
Aldose 1-epimerase
Gene
galM, NRG857_03345
Organism
Escherichia coli O83:H1 (strain NRG 857C / AIEC)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose By similarity.UniRule annotation

Catalytic activityi

Alpha-D-glucose = beta-D-glucose.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. aldose 1-epimerase activity Source: UniProtKB-EC
  2. carbohydrate binding Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. galactose metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationImported

Keywords - Biological processi

Carbohydrate metabolismUniRule annotation

Enzyme and pathway databases

UniPathwayiUPA00242.

Names & Taxonomyi

Protein namesi
Recommended name:
Aldose 1-epimeraseUniRule annotation (EC:5.1.3.3UniRule annotation)
Alternative name(s):
Galactose mutarotase
Gene namesi
Name:galMImported
Ordered Locus Names:NRG857_03345Imported
OrganismiEscherichia coli O83:H1 (strain NRG 857C / AIEC)Imported
Taxonomic identifieri685038 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000008614: Chromosome

Structurei

3D structure databases

ProteinModelPortaliE4PAA5.

Family & Domainsi

Sequence similaritiesi

Belongs to the aldose epimerase family.UniRule annotation

Phylogenomic databases

KOiK01785.

Family and domain databases

Gene3Di2.70.98.10. 1 hit.
InterProiIPR018052. Ald1_epimerase_CS.
IPR013458. Ald_epimerase_bac.
IPR015443. Aldose_1-epimerase.
IPR008183. Aldose_1/G6P_1-epimerase.
IPR011013. Gal_mutarotase_SF_dom.
IPR014718. Glyco_hydro-type_carb-bd_sub.
[Graphical view]
PfamiPF01263. Aldose_epim. 1 hit.
[Graphical view]
PIRSFiPIRSF005096. GALM. 1 hit.
SUPFAMiSSF74650. SSF74650. 1 hit.
TIGRFAMsiTIGR02636. galM_Leloir. 1 hit.
PROSITEiPS00545. ALDOSE_1_EPIMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E4PAA5-1 [UniParc]FASTAAdd to Basket

« Hide

MLNETPALAP DGQPYRLLTL RNNAGMVVTL MDWGATLLSA RIPLSDGSVR    50
EALLGCASPE CYQDQAAFLG ASIGRYANRI ANSRYTFDGE TVTLSPSQGV 100
NQLHGGPEGF DKRRWQIVNQ NDRQVLFALS SDDGDQGFPG NLGATVQYRL 150
TDDNRISITY RATVDKPCPV NMTNHVYFNL DGEQSDVRNH KLQILAEEYL 200
PVDEGGIPHD GLKSVAGTSF DFRNAKIIAS EFLADDDQRK VKGYDHAFLL 250
QAKGDGKKVA AHVWSADEKL QLKVYTTAPA LQFYSGNFLG GTPSRGTEPY 300
ADWQGLALES EFLPDSPNHP EWPQPDCFLR PGEEYSSLTE YQFIAQ 346
Length:346
Mass (Da):38,231
Last modified:February 8, 2011 - v1
Checksum:iEF527FDAA3B9F57D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001855 Genomic DNA. Translation: ADR26100.1.
RefSeqiYP_006119034.1. NC_017634.1.

Genome annotation databases

EnsemblBacteriaiADR26100; ADR26100; NRG857_03345.
GeneIDi12877084.
KEGGieln:NRG857_03345.
PATRICi45444949. VBIEscCol181005_0678.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001855 Genomic DNA. Translation: ADR26100.1 .
RefSeqi YP_006119034.1. NC_017634.1.

3D structure databases

ProteinModelPortali E4PAA5.
ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADR26100 ; ADR26100 ; NRG857_03345 .
GeneIDi 12877084.
KEGGi eln:NRG857_03345.
PATRICi 45444949. VBIEscCol181005_0678.

Phylogenomic databases

KOi K01785.

Enzyme and pathway databases

UniPathwayi UPA00242 .

Family and domain databases

Gene3Di 2.70.98.10. 1 hit.
InterProi IPR018052. Ald1_epimerase_CS.
IPR013458. Ald_epimerase_bac.
IPR015443. Aldose_1-epimerase.
IPR008183. Aldose_1/G6P_1-epimerase.
IPR011013. Gal_mutarotase_SF_dom.
IPR014718. Glyco_hydro-type_carb-bd_sub.
[Graphical view ]
Pfami PF01263. Aldose_epim. 1 hit.
[Graphical view ]
PIRSFi PIRSF005096. GALM. 1 hit.
SUPFAMi SSF74650. SSF74650. 1 hit.
TIGRFAMsi TIGR02636. galM_Leloir. 1 hit.
PROSITEi PS00545. ALDOSE_1_EPIMERASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of adherent-invasive Escherichia coli and comparative genomic analysis with other E. coli pathotypes."
    Nash J.H., Villegas A., Kropinski A.M., Aguilar-Valenzuela R., Konczy P., Mascarenhas M., Ziebell K., Torres A.G., Karmali M.A., Coombes B.K.
    BMC Genomics 11:667-667(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NRG 857C / AIEC.

Entry informationi

Entry nameiE4PAA5_ECO8N
AccessioniPrimary (citable) accession number: E4PAA5
Entry historyi
Integrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: June 11, 2014
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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