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E4PAA5 (E4PAA5_ECO8N) Unreviewed, UniProtKB/TrEMBL

Last modified October 16, 2013. Version 15. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Aldose 1-epimerase PIRNR PIRNR005096

EC=5.1.3.3 PIRNR PIRNR005096
Alternative name(s):
Galactose mutarotase PIRNR PIRNR005096
Gene names
Name:galM EMBL ADR26100.1
Ordered Locus Names:NRG857_03345 EMBL ADR26100.1
OrganismEscherichia coli O83:H1 (strain NRG 857C / AIEC) [Complete proteome] [HAMAP] EMBL ADR26100.1
Taxonomic identifier685038 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

Protein attributes

Sequence length346 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose By similarity. PIRNR PIRNR005096

Catalytic activity

Alpha-D-glucose = beta-D-glucose. PIRNR PIRNR005096

Pathway

Carbohydrate metabolism; hexose metabolism. PIRNR PIRNR005096

Sequence similarities

Belongs to the aldose epimerase family. PIRNR PIRNR005096

Ontologies

Keywords
   Biological processCarbohydrate metabolism PIRNR PIRNR005096
   Molecular functionIsomerase PIRNR PIRNR005096 EMBL ADR26100.1
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgalactose metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionaldose 1-epimerase activity

Inferred from electronic annotation. Source: UniProtKB-EC

carbohydrate binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
E4PAA5 [UniParc].

Last modified February 8, 2011. Version 1.
Checksum: EF527FDAA3B9F57D

FASTA34638,231
        10         20         30         40         50         60 
MLNETPALAP DGQPYRLLTL RNNAGMVVTL MDWGATLLSA RIPLSDGSVR EALLGCASPE 

        70         80         90        100        110        120 
CYQDQAAFLG ASIGRYANRI ANSRYTFDGE TVTLSPSQGV NQLHGGPEGF DKRRWQIVNQ 

       130        140        150        160        170        180 
NDRQVLFALS SDDGDQGFPG NLGATVQYRL TDDNRISITY RATVDKPCPV NMTNHVYFNL 

       190        200        210        220        230        240 
DGEQSDVRNH KLQILAEEYL PVDEGGIPHD GLKSVAGTSF DFRNAKIIAS EFLADDDQRK 

       250        260        270        280        290        300 
VKGYDHAFLL QAKGDGKKVA AHVWSADEKL QLKVYTTAPA LQFYSGNFLG GTPSRGTEPY 

       310        320        330        340 
ADWQGLALES EFLPDSPNHP EWPQPDCFLR PGEEYSSLTE YQFIAQ 

« Hide

References

[1]"Genome sequence of adherent-invasive Escherichia coli and comparative genomic analysis with other E. coli pathotypes."
Nash J.H., Villegas A., Kropinski A.M., Aguilar-Valenzuela R., Konczy P., Mascarenhas M., Ziebell K., Torres A.G., Karmali M.A., Coombes B.K.
BMC Genomics 11:667-667(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: NRG 857C / AIEC.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001855 Genomic DNA. Translation: ADR26100.1.
RefSeqYP_006119034.1. NC_017634.1.

3D structure databases

ProteinModelPortalE4PAA5.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADR26100; ADR26100; NRG857_03345.
GeneID12877084.
KEGGeln:NRG857_03345.
PATRIC45444949. VBIEscCol181005_0678.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01785.

Enzyme and pathway databases

UniPathwayUPA00242.

Family and domain databases

Gene3D2.70.98.10. 1 hit.
InterProIPR018052. Ald1_epimerase_CS.
IPR013458. Ald_epimerase_bac.
IPR015443. Aldose_1-epimerase.
IPR008183. Aldose_1/G6P_1-epimerase.
IPR011013. Gal_mutarotase_SF_dom.
IPR014718. Glyco_hydro-type_carb-bd_sub.
[Graphical view]
PANTHERPTHR10091. PTHR10091. 1 hit.
PfamPF01263. Aldose_epim. 1 hit.
[Graphical view]
PIRSFPIRSF005096. GALM. 1 hit.
SUPFAMSSF74650. SSF74650. 1 hit.
TIGRFAMsTIGR02636. galM_Leloir. 1 hit.
PROSITEPS00545. ALDOSE_1_EPIMERASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameE4PAA5_ECO8N
AccessionPrimary (citable) accession number: E4PAA5
Entry history
Integrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: October 16, 2013
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)