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E4P0Y9 (E4P0Y9_BIFBP) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 20. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Aspartate--tRNA ligase HAMAP-Rule MF_00044
EC=6.1.1.12 HAMAP-Rule MF_00044
Alternative name(s):
Aspartyl-tRNA synthetase HAMAP-Rule MF_00044
Gene names
Name:aspS HAMAP-Rule MF_00044
Ordered Locus Names:BBPR_0665
OrganismBifidobacterium bifidum (strain PRL2010) [Complete proteome] [HAMAP] EMBL ADP35756.1
Taxonomic identifier702459 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Bifidobacteriales › Bifidobacteriaceae › Bifidobacterium ›

Protein attributes

Sequence length598 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-aspartate + tRNA(Asp) = AMP + diphosphate + L-aspartyl-tRNA(Asp). HAMAP-Rule MF_00044 SAAS SAAS004524

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_00044 SAAS SAAS004524

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00044 SAAS SAAS004524.

Sequence similarities

Belongs to the class-II aminoacyl-tRNA synthetase family. RuleBase RU003746 HAMAP-Rule MF_00044

Sequences

Sequence LengthMass (Da)Tools
E4P0Y9 [UniParc].

Last modified February 8, 2011. Version 1.
Checksum: 7D9606DD16C1E7E9

FASTA59866,714
        10         20         30         40         50         60 
MSQTAYRTHH ATEVTEALVG QKVTLAGWVD RRRDHGGVAF IDLRDNTGLV QIVIYDEEMA 

        70         80         90        100        110        120 
RPLRSEFVIQ VTGEVRLRPD GNENTHLATG KIEVVVETID VLAKSDALPF QVSTALENES 

       130        140        150        160        170        180 
ENKLPGEDVR LKYRYLDLRR PSMQHNLKLR SDMAKAARHA LEEMDFTEVE TPTFIKSTPE 

       190        200        210        220        230        240 
GARDFVVPAR LVPGSWYALP QSPQLLKQLL MVSGVERYYQ LARCYRDEDF RADRQPEFTQ 

       250        260        270        280        290        300 
LDMEMAFVDQ EDVMAMAEKV IAAIWKSAGY DVQLPIQRIT WQDAMDKYGS DKPDLRFGNP 

       310        320        330        340        350        360 
LVELTEYFKD TPFRVFQADY VGAVVFKGGA ATPRRQFDAW QEWAKQRGAK GLAYVSFTED 

       370        380        390        400        410        420 
GELKGPVAKN LSDSEREGLM AAVGAESGDA VFFAAGSRES SQLLLGAVRV ELARRAGLLD 

       430        440        450        460        470        480 
PKKFAFTWVV DFPLFKPTDD PDDDDVAVGH SKWTSMHHPF TMPSKDWIDK FDQDPEHAMS 

       490        500        510        520        530        540 
DSYDIVCNGE EMGGGSVRIH RDDIQDRVLN VLGIAPEEAK EKFGFLLDAF KFGAPPHAGI 

       550        560        570        580        590 
ALGWDRTVSI LAGADTIRDV IAFPKAGGGR DPLTGAPAPI SDEQRAETGV DYDPDAED

« Hide

References

[1]"Genome analysis of Bifidobacterium bifidum PRL2010 reveals metabolic pathways for host-derived glycan foraging."
Turroni F., Bottacini F., Foroni E., Mulder I., Kim J.H., Zomer A., Sanchez B., Bidossi A., Ferrarini A., Giubellini V., Delledonne M., Henrissat B., Coutinho P., Oggioni M., Fitzgerald G.F., Mills D., Margolles A., Kelly D., van Sinderen D., Ventura M.
Proc. Natl. Acad. Sci. U.S.A. 107:19514-19519(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PRL2010.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001840 Genomic DNA. Translation: ADP35756.1.
RefSeqYP_003970793.1. NC_014638.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADP35756; ADP35756; BBPR_0665.
GeneID9888813.
KEGGbbp:BBPR_0665.
PATRIC42576982. VBIBifBif153886_0694.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000275159.
KOK01876.

Enzyme and pathway databases

BioCycBBIF702459:GHBC-620-MONOMER.

Family and domain databases

Gene3D2.40.50.140. 1 hit.
3.30.1360.30. 1 hit.
HAMAPMF_00044_B. Asp_tRNA_synth_B.
InterProIPR004364. aa-tRNA-synt_II.
IPR018150. aa-tRNA-synt_II-like.
IPR006195. aa-tRNA-synth_II.
IPR004524. Asp-tRNA-ligase_IIb_bac/mt.
IPR002312. Asp/Asn-tRNA-synth_IIb.
IPR004115. GAD_dom.
IPR012340. NA-bd_OB-fold.
IPR004365. NA-bd_OB_tRNA-helicase.
[Graphical view]
PANTHERPTHR22594. PTHR22594. 1 hit.
PTHR22594:SF5. PTHR22594:SF5. 1 hit.
PfamPF02938. GAD. 1 hit.
PF00152. tRNA-synt_2. 1 hit.
PF01336. tRNA_anti. 1 hit.
[Graphical view]
PRINTSPR01042. TRNASYNTHASP.
SUPFAMSSF50249. Nucleic_acid_OB. 1 hit.
SSF55261. SSF55261. 1 hit.
TIGRFAMsTIGR00459. aspS_bact. 1 hit.
PROSITEPS50862. AA_TRNA_LIGASE_II. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameE4P0Y9_BIFBP
AccessionPrimary (citable) accession number: E4P0Y9
Entry history
Integrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: May 1, 2013
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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