E4P0F8 (E4P0F8_BIFBP) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Exo-alpha-sialidase EMBL ADP36806.1
EC=3.2.1.18 EMBL ADP36806.1

Gene names

Ordered Locus Names:

BBPR_1793

Organism

Bifidobacterium bifidum (strain PRL2010) [Complete proteome] [HAMAP] EMBL ADP36806.1

Taxonomic identifier

702459 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Bifidobacteriales › Bifidobacteriaceae › Bifidobacterium › Bifidobacterium bifidum

Protein attributes

Sequence length	1795 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Glycosidase EMBL ADP36806.1 Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular_function	exo-alpha-(2->3)-sialidase activity Inferred from electronic annotation. Source: EC exo-alpha-(2->6)-sialidase activity Inferred from electronic annotation. Source: EC exo-alpha-(2->8)-sialidase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	E4P0F8 [UniParc]. Last modified February 8, 2011. Version 1. Checksum: FF63A7F503B9CEEE	FASTA	1,795	189,291
	10 20 30 40 50 60 MTTIFRRATA KTLMRKLSGL LVAIAMLAVL PAGTISANAA DEPPQEYLQL TLTRTDSNGT 70 80 90 100 110 120 PAEVGDKLTY SLGYKNVSDT GFIVHPTASN LNNVATPQSA SNPNPMCRWG NLAAGASAAC 130 140 150 160 170 180 TWSASKEFAY HVVTEDDVAN GFTPTATVSA TTQDGTNGVL QSVDITGETV PAVPATSTLR 190 200 210 220 230 240 VAMQRTDTLG DNVKIGDRLT FNFTYTNKTA QKIYAYPSES NIERVDVVSF PRNSCRSGVE 250 260 270 280 290 300 ANQTASCGFA YHVITAEDVV ARRYTPTATF RATSDRDGTQ VLQDDMTFTT GTVTVAGPAD 310 320 330 340 350 360 DAASTPTERK DGEPLLLATN KQIGNTDYYR IPAIAQAPNG WILAAWDLRP KLAADAPNPN 370 380 390 400 410 420 SIVQRISKDG GKSWETLAYV AQGRSATNKY GYSDPSYVVD EEAGKIFLFC VKSYDQGYFG 430 440 450 460 470 480 SVLGVEDARN VLQAVVMESD DNGATWSEPR NITKDITKGH EDEWKSRFAS SGHGIQLKYG 490 500 510 520 530 540 QYKGRLIQQY AVRTTSNTNI AVSVYSDDHG KTWKAGNPVT EANMDENKVV ELSDGRVMLN 550 560 570 580 590 600 SRPGAAGYRR VAISEDGGVN YGPIKSETQL PDPNNNAQIT RAFPNAPEGS AKAKVLLYSA 610 620 630 640 650 660 PRASNEGRAN GVVRVSFDDG TTWSAGKLFK EGSMAYSVIT ALNDAAGGGY GLLYEGESIT 670 680 690 700 710 720 YTRVSMEWLG YLTATASGTA TVKEGEGTLT APVTVTNDGL TDYTNVTVTP TGLPSGWSAE 730 740 750 760 770 780 AVNVGNLAAG QSATVNVPVT VPAAAVSGTV AKATMKITGK YAQSEDTLHS FAEGELAVTV 790 800 810 820 830 840 TEPDPAAKRL KLTIERTDDN GAPVKVGDTL TYRITYENVG TQSFAVYPRK SNLDGVTTPQ 850 860 870 880 890 900 SASNPAPVCR WSRLDPGTTG ACVSGNGKRL AYHTVTEADA TAGSFTPSAT IDATADTSGE 910 920 930 940 950 960 TVLESVSITG DPVTVSQPVE LPADIAAWKT RNEALDDWQT LSEKLAKTDR INWLFTGDSI 970 980 990 1000 1010 1020 THGVQLTRGY RTYSELFANH LDTASVRGVS RANDVVMNTG ISSADASWPL KDGAFEKWVS 1030 1040 1050 1060 1070 1080 DKHPDVVFLT FGMNDGRTGQ AFTVDQYTAN LSTLIDKIRD LGAIPVLQTQ NYTTNTTFNA 1090 1100 1110 1120 1130 1140 NLDTYFDAER RLALDKNVLL VDFNKQWLEL GGGNRESGTY MGAGNDIHPG ENGHIEWAKF 1150 1160 1170 1180 1190 1200 TLGALNMIAN DDPLARWSSS DTTLDKPTVT VDADGNGLKG SDGLEPAPAA AKSVGKFLSG 1210 1220 1230 1240 1250 1260 AQYVDLGGDV VSAVAGKRES NVTIRFRASA TGQPQTLFSL GDSDSATRAT VRLSATGLVQ 1270 1280 1290 1300 1310 1320 FLNSGNTGDF YTVGTNDLAD GAWHTVSVNF VANGFTIYVD GAAMRAISGG AGTQLNVPGA 1330 1340 1350 1360 1370 1380 ITVNTATAGA IRGADSAGGA QQLTGIVDYV AAWSRTLTDA EAKRISAETS AVAVTKVDAA 1390 1400 1410 1420 1430 1440 VNALQPIISD TGARKNIVFV GGETIEGGYT DHLIAKNIVQ LLDERVRWEY VTGLSATDRE 1450 1460 1470 1480 1490 1500 LQRAKFFVAA GQGGLTAKQM DEDYAAMVGE YSPDILFLAP DLYDADGILA ESDAAAFAGH 1510 1520 1530 1540 1550 1560 IRSVAAKAKE AGAKVVLVTP VTVRGGEDEY AGAMRTVAKE DDLPLIDAQA WIGKVVAADA 1570 1580 1590 1600 1610 1620 SVKTAWFNKA GQLNYAGHLG YARFMMRSLD LYPSNVSGSR IASLPYDTAN VTLVGASENG 1630 1640 1650 1660 1670 1680 GELPVGRVEG TDRAHIDTMQ IGAAASLVVT DSYAVYEIGE DGGRTLVADG LKPADVLADG 1690 1700 1710 1720 1730 1740 IDVTVNDTAA HRYEVVGSAN VPEGADAVTV TYTATLAAVE EPEPGPDPDP TPDPSEKPDG 1750 1760 1770 1780 1790 DGTGDGTGAG AGDVQKPTPD AVAKTGADVF GLLAAVAVLL AAGGVTLSLR RRANR

References

[1]

"Genome analysis of Bifidobacterium bifidum PRL2010 reveals metabolic pathways for host-derived glycan foraging." Turroni F., Bottacini F., Foroni E., Mulder I., Kim J.H., Zomer A., Sanchez B., Bidossi A., Ferrarini A., Giubellini V., Delledonne M., Henrissat B., Coutinho P., Oggioni M., Fitzgerald G.F., Mills D., Margolles A., Kelly D., van Sinderen D., Ventura M. Proc. Natl. Acad. Sci. U.S.A. 107:19514-19519(2010) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PRL2010.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001840 Genomic DNA. Translation: ADP36806.1.
RefSeq	YP_003971843.1. NC_014638.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADP36806; ADP36806; BBPR_1793.
GeneID	9889912.
KEGG	bbp:BBPR_1793.
PATRIC	42579372. VBIBifBif153886_1852.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000166244.
KO	K01186.
Enzyme and pathway databases
BioCyc	BBIF702459:GHBC-1683-MONOMER.
Family and domain databases
Gene3D	2.120.10.10. 1 hit. 2.60.120.200. 1 hit. 2.60.40.10. 1 hit. 3.40.50.1110. 2 hits.
InterPro	IPR018905. A-galactase_NEW3. IPR008985. ConA-like_lec_gl_sf. IPR013320. ConA-like_subgrp. IPR013783. Ig-like_fold. IPR001791. Laminin_G. IPR013831. SGNH_hydro-type_esterase_dom. IPR026856. Sialidase_fam. IPR011040. Sialidases. [Graphical view]
PANTHER	PTHR10628. PTHR10628. 1 hit.
Pfam	PF10633. NPCBM_assoc. 1 hit. [Graphical view]
SMART	SM00282. LamG. 1 hit. [Graphical view]
SUPFAM	SSF49899. ConA_like_lec_gl. 1 hit. SSF50939. Sialidase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

E4P0F8_BIFBP

Accession

Primary (citable) accession number: E4P0F8

Entry history

Integrated into UniProtKB/TrEMBL:	February 8, 2011
Last sequence update:	February 8, 2011
Last modified:	May 1, 2013
This is version 16 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)