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E4NY78 (E4NY78_BIFBP) Unreviewed, UniProtKB/TrEMBL

Last modified May 29, 2013. Version 16. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Beta-galactosidase PIRNR PIRNR001084
Short name=Beta-gal PIRNR PIRNR001084
EC=3.2.1.23 PIRNR PIRNR001084
Gene names
Name:lacZ5
Ordered Locus Names:BBPR_1355
OrganismBifidobacterium bifidum (strain PRL2010) [Complete proteome] [HAMAP] EMBL ADP36405.1
Taxonomic identifier702459 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Bifidobacteriales › Bifidobacteriaceae › Bifidobacterium ›

Protein attributes

Sequence length689 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides. PIRNR PIRNR001084

Sequence similarities

Belongs to the glycosyl hydrolase 42 family. PIRNR PIRNR001084

Ontologies

Keywords
   Molecular functionGlycosidase PIRNR PIRNR001084 EMBL ADP36405.1
Hydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgalactose metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentbeta-galactosidase complex

Inferred from electronic annotation. Source: InterPro

   Molecular_functionbeta-galactosidase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1611Proton donor By similarity PIRSR PIRSR001084-1
Active site3201Nucleophile By similarity PIRSR PIRSR001084-1
Binding site1221Substrate By similarity PIRSR PIRSR001084-2
Binding site1601Substrate By similarity PIRSR PIRSR001084-2
Binding site3281Substrate By similarity PIRSR PIRSR001084-2

Sequences

Sequence LengthMass (Da)Tools
E4NY78 [UniParc].

Last modified February 8, 2011. Version 1.
Checksum: C13E7161F5B63947

FASTA68977,234
        10         20         30         40         50         60 
MSKRRKHSWP QPLKGAESRL WYGGDYNPDQ WPEEVWDDDI RLMKKAGVNL VSVGIFSWAK 

        70         80         90        100        110        120 
IEPEEGKYDF DWLDRAIDKL GKAGIAVDLA SATASPPMWL TQAHPEVLWK DERGDTVWPG 

       130        140        150        160        170        180 
AREHWRPTSP VFREYALNLC RRMAEHYKGN PYVVAWHVSN EYGCHNRFDY SDDAMRAFQK 

       190        200        210        220        230        240 
WCKKRYKTID AVNEAWGTAF WAQHMNDFSE IIPPRYIGDG NFMNPGKLLD YKRFSSDALK 

       250        260        270        280        290        300 
ELYIAERDVL ESITPGLPLT TNFMVSAGGS MLDYDDWGAE VDFVSNDHYF TPGEDHFDEV 

       310        320        330        340        350        360 
AYAASLMDGI SRKEPWFQME HSTSAVNWRP INYRAEPGSV VRDSLAQVAM GADAICYFQW 

       370        380        390        400        410        420 
RQSKAGAEKW HSSMVPHAGE DSQIFRDVCE LGADLGRLSD EGLMGTKTVK SKVAVVFDYE 

       430        440        450        460        470        480 
SQWATEYTAN PTQQVDHWTE PLDWFRALAD NGITADVVPV RSDWDSYEIA VLPCVYLLSE 

       490        500        510        520        530        540 
ETSRRVREFV ANGGKLFVTY YTGLSDENDH IWLGGYPGSI RDVVGVRVEE FAPMGNDMPG 

       550        560        570        580        590        600 
ALDHLDLDNG TVAHDFADVI TSTADTSTVL ASYKAERWTG MNEVPAIVAN GYGDGRTVYV 

       610        620        630        640        650        660 
GCRLGRQGLA KSLPAMLGSM GLSDLAGDGR VLRVERADAA AASHFEFVFN RTHEPVTVDV 

       670        680 
EGEAIAASLA HVDDGRATID PTGVVVLRR

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References

[1]"Genome analysis of Bifidobacterium bifidum PRL2010 reveals metabolic pathways for host-derived glycan foraging."
Turroni F., Bottacini F., Foroni E., Mulder I., Kim J.H., Zomer A., Sanchez B., Bidossi A., Ferrarini A., Giubellini V., Delledonne M., Henrissat B., Coutinho P., Oggioni M., Fitzgerald G.F., Mills D., Margolles A., Kelly D., van Sinderen D., Ventura M.
Proc. Natl. Acad. Sci. U.S.A. 107:19514-19519(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PRL2010.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001840 Genomic DNA. Translation: ADP36405.1.
RefSeqYP_003971442.1. NC_014638.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADP36405; ADP36405; BBPR_1355.
GeneID9889488.
KEGGbbp:BBPR_1355.
PATRIC42578442. VBIBifBif153886_1403.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000117811.
KOK12308.

Enzyme and pathway databases

BioCycBBIF702459:GHBC-1312-MONOMER.

Family and domain databases

Gene3D3.20.20.80. 1 hit.
InterProIPR013739. Beta_galactosidase_C.
IPR013738. Beta_galactosidase_Trimer.
IPR003476. Glyco_hydro_42.
IPR013529. Glyco_hydro_42_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamPF02449. Glyco_hydro_42. 1 hit.
PF08533. Glyco_hydro_42C. 1 hit.
PF08532. Glyco_hydro_42M. 1 hit.
[Graphical view]
PIRSFPIRSF001084. B-galactosidase. 1 hit.
SUPFAMSSF51445. Glyco_hydro_cat. 1 hit.
ProtoNetSearch...

Entry information

Entry nameE4NY78_BIFBP
AccessionPrimary (citable) accession number: E4NY78
Entry history
Integrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: May 29, 2013
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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