E4NXZ0 (E4NXZ0_BIFBP) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Alanine racemase RuleBase RU000608
EC=5.1.1.1 RuleBase RU000608

Gene names

Name:	alr
Ordered Locus Names:	BBPR_1338

Organism

Bifidobacterium bifidum (strain PRL2010) [Complete proteome] [HAMAP] EMBL ADP36388.1

Taxonomic identifier

702459 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Bifidobacteriales › Bifidobacteriaceae › Bifidobacterium › Bifidobacterium bifidum

Protein attributes

Sequence length	452 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-alanine = D-alanine. RuleBase RU000608 SAAS SAAS020622
Cofactor	Pyridoxal phosphate By similarity. RuleBase RU000608 SAAS SAAS020622
Pathway	Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. RuleBase RU004247 SAAS SAAS020622
Sequence similarities	Belongs to the alanine racemase family. RuleBase RU004188

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU000608 SAAS SAAS020622
Molecular function	Isomerase RuleBase RU000608 SAAS SAAS020622 EMBL ADP36388.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	D-alanine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	alanine racemase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	E4NXZ0 [UniParc]. Last modified February 8, 2011. Version 1. Checksum: 03D7FFB6AEAA4E45	FASTA	452	48,115
	10 20 30 40 50 60 MTLNAASELQ FSSPAGEANY RAARRRYPAQ AIVDLATLRD NMAHLVDVVG GPHSGTAVMG 70 80 90 100 110 120 VVKADAYGHG LLPAALAALA GGATWLGTAQ SHEALLLRKL GIGPDRCRIL TWVYNGMDVP 130 140 150 160 170 180 FDELIDNDID ISVGSLAGID ALADAARRLG KPARVHVKVD SGFGRNGFTP AGFDAALAKL 190 200 210 220 230 240 VPLAHEGVLH IVGQWSHLAV ADSPDVPEFV ASTDRQIESF TEFTRRMEAA GIAPEIRHLA 250 260 270 280 290 300 NTAATLNRPE IHLELTRPGI GLYGYEPDPA MGTPRDWHLK PAMTLQAQLG TVKDVEAGHG 310 320 330 340 350 360 VSYGRTYLTP DNTSTAIVPL GYADGIHRSA SGFDMQGAKH VEKAGGPVRV MTSAGPRLLH 370 380 390 400 410 420 VCGRVCMDQF IVDLHGSAAE LGVHEGDTVE LFGPGRGEQY GEPTADDWAR AADTISYEVF 430 440 450 TCLRNRIPRL YLHAADVLPA ADLAKLDPAS LL

References

[1]

"Genome analysis of Bifidobacterium bifidum PRL2010 reveals metabolic pathways for host-derived glycan foraging." Turroni F., Bottacini F., Foroni E., Mulder I., Kim J.H., Zomer A., Sanchez B., Bidossi A., Ferrarini A., Giubellini V., Delledonne M., Henrissat B., Coutinho P., Oggioni M., Fitzgerald G.F., Mills D., Margolles A., Kelly D., van Sinderen D., Ventura M. Proc. Natl. Acad. Sci. U.S.A. 107:19514-19519(2010) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PRL2010.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001840 Genomic DNA. Translation: ADP36388.1.
RefSeq	YP_003971425.1. NC_014638.1.
3D structure databases
ProteinModelPortal	E4NXZ0.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADP36388; ADP36388; BBPR_1338.
GeneID	9889468.
KEGG	bbp:BBPR_1338.
PATRIC	42578400. VBIBifBif153886_1385.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000031444.
KO	K01775.
Enzyme and pathway databases
BioCyc	BBIF702459:GHBC-1258-MONOMER.
UniPathway	UPA00042; UER00497.
Family and domain databases
Gene3D	2.40.37.10. 1 hit.
HAMAP	MF_01201. Ala_racemase.
InterPro	IPR000821. Ala_racemase. IPR009006. Ala_racemase/Decarboxylase_C. IPR011079. Ala_racemase_C. IPR001608. Ala_racemase_N. IPR020622. Ala_racemase_pyridoxalP-BS. [Graphical view]
Pfam	PF00842. Ala_racemase_C. 1 hit. PF01168. Ala_racemase_N. 1 hit. [Graphical view]
PRINTS	PR00992. ALARACEMASE.
SMART	SM01005. Ala_racemase_C. 1 hit. [Graphical view]
SUPFAM	SSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMs	TIGR00492. alr. 1 hit.
PROSITE	PS00395. ALANINE_RACEMASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

E4NXZ0_BIFBP

Accession

Primary (citable) accession number: E4NXZ0

Entry history

Integrated into UniProtKB/TrEMBL:	February 8, 2011
Last sequence update:	February 8, 2011
Last modified:	May 1, 2013
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)