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E4NXZ0 (E4NXZ0_BIFBP) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length452 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201 RuleBase RU004247 SAAS SAAS020622

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS020622

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201 RuleBase RU004247

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site631Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site3031Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1651Substrate By similarity HAMAP-Rule MF_01201
Binding site3671Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue631N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
E4NXZ0 [UniParc].

Last modified February 8, 2011. Version 1.
Checksum: 03D7FFB6AEAA4E45

FASTA45248,115
        10         20         30         40         50         60 
MTLNAASELQ FSSPAGEANY RAARRRYPAQ AIVDLATLRD NMAHLVDVVG GPHSGTAVMG 

        70         80         90        100        110        120 
VVKADAYGHG LLPAALAALA GGATWLGTAQ SHEALLLRKL GIGPDRCRIL TWVYNGMDVP 

       130        140        150        160        170        180 
FDELIDNDID ISVGSLAGID ALADAARRLG KPARVHVKVD SGFGRNGFTP AGFDAALAKL 

       190        200        210        220        230        240 
VPLAHEGVLH IVGQWSHLAV ADSPDVPEFV ASTDRQIESF TEFTRRMEAA GIAPEIRHLA 

       250        260        270        280        290        300 
NTAATLNRPE IHLELTRPGI GLYGYEPDPA MGTPRDWHLK PAMTLQAQLG TVKDVEAGHG 

       310        320        330        340        350        360 
VSYGRTYLTP DNTSTAIVPL GYADGIHRSA SGFDMQGAKH VEKAGGPVRV MTSAGPRLLH 

       370        380        390        400        410        420 
VCGRVCMDQF IVDLHGSAAE LGVHEGDTVE LFGPGRGEQY GEPTADDWAR AADTISYEVF 

       430        440        450 
TCLRNRIPRL YLHAADVLPA ADLAKLDPAS LL 

« Hide

References

[1]"Genome analysis of Bifidobacterium bifidum PRL2010 reveals metabolic pathways for host-derived glycan foraging."
Turroni F., Bottacini F., Foroni E., Mulder I., Kim J.H., Zomer A., Sanchez B., Bidossi A., Ferrarini A., Giubellini V., Delledonne M., Henrissat B., Coutinho P., Oggioni M., Fitzgerald G.F., Mills D., Margolles A., Kelly D., van Sinderen D., Ventura M.
Proc. Natl. Acad. Sci. U.S.A. 107:19514-19519(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PRL2010 EMBL ADP36388.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001840 Genomic DNA. Translation: ADP36388.1.
RefSeqYP_003971425.1. NC_014638.1.

3D structure databases

ProteinModelPortalE4NXZ0.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADP36388; ADP36388; BBPR_1338.
GeneID9889468.
KEGGbbp:BBPR_1338.
PATRIC42578400. VBIBifBif153886_1385.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000031444.
KOK01775.

Enzyme and pathway databases

BioCycBBIF702459:GHBC-1292-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameE4NXZ0_BIFBP
AccessionPrimary (citable) accession number: E4NXZ0
Entry history
Integrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: July 9, 2014
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)