Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054) (Streptomyces setae)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei144 – 1441UniRule annotation
Active sitei589 – 5891UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciKSET452652:GJFD-4653-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
Ordered Locus Names:KSE_46510Imported
OrganismiKitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054) (Streptomyces setae)Imported
Taxonomic identifieri452652 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeKitasatospora
ProteomesiUP000007076: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.
OMAiCGMGVIA.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E4NG02-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTAPVPTPAD SPSSIADADN AALRADIRRL GDLLGETLVR QEGPELLGLV
60 70 80 90 100
EQVRLLSRTD GEATAQLLAE IDLDTAAKLV RAFSTYFHLA NVTEQVHRGR
110 120 130 140 150
EFAARRALEG SVLSQTVDQL KEADPKHLAD TLANLSVRPV FTAHPTEAAR
160 170 180 190 200
RSVLNKLRRV GELLERIHRE QAATGRVDSA RQTSARRQAD RRLAEVIDLL
210 220 230 240 250
WQTDELRIAR PEPTDEARNA VYYLDELYRE AVPEVLEELH EELARVGLTL
260 270 280 290 300
PEGVRPLTFG TWIGGDRDGN PNVTPRVTWD VLNLQHEYGI KDALEAVDDL
310 320 330 340 350
RASLSTSVRL AGASEELLAS LDADLAHLPE LSPRYKRMNA EEPYRLKATC
360 370 380 390 400
IRIKLENTRD RLAAGTAPTP GRDYVGTRDL IADLRLVQDS LRAHRGGLIA
410 420 430 440 450
DGRLARTIRT IEAFGLQLAT MDVREHAEAH HHALGQLFDR LGEEAWRYTD
460 470 480 490 500
MPREYRQRLL SKEMRSRRPL APTPAPLDAA GAKTLGVFTT IREGFERFGD
510 520 530 540 550
EIVESYIISM CQGADDVFAA AVLAREAGLI DLHAGIAKIG IVPLLETTDE
560 570 580 590 600
LQEADRILDE MLSDPSYRLL VSLRGDVQEV MLGYSDSSKF GGITTSQWEI
610 620 630 640 650
HRAQRRLRDV AHRYGIRLRL FHGRGGTVGR GGGPSHEAIL AQPWGTLEGE
660 670 680 690 700
IKVTEQGEVI SDKYLLPSLA RENLELTLSA TLAASALHTA PRQAPEELAR
710 720 730 740 750
WDAAMDRVSE AAHTAYRALV EQEDLPKYFF AATPVDQLAS LHLGSRPSRR
760 770 780 790 800
PDSGAGLDGL RAIPWVFGWT QSRQIVPGWY GVGSGLAAAR EAGLGDVLDE
810 820 830 840 850
MHGNWHFFRN FLSNVAMTLA KTDLRIARHY VEQLVPAELH HVFEQIVAEH
860 870 880 890 900
DLTLREVLRL TGESELLEHN DVLKQTFTVR DAYLDPISYL QVALLRRQRE
910 920 930
EVAAGRPEDP LRARALLLTV NGIAAGLRNT G
Length:931
Mass (Da):103,331
Last modified:February 8, 2011 - v1
Checksum:i90BDCB858FE97CA8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP010968 Genomic DNA. Translation: BAJ30432.1.
RefSeqiWP_014137731.1. NC_016109.1.
YP_004906388.1. NC_016109.1.

Genome annotation databases

EnsemblBacteriaiBAJ30432; BAJ30432; KSE_46510.
GeneIDi11352250.
KEGGiksk:KSE_46510.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP010968 Genomic DNA. Translation: BAJ30432.1.
RefSeqiWP_014137731.1. NC_016109.1.
YP_004906388.1. NC_016109.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAJ30432; BAJ30432; KSE_46510.
GeneIDi11352250.
KEGGiksk:KSE_46510.

Phylogenomic databases

KOiK01595.
OMAiCGMGVIA.

Enzyme and pathway databases

BioCyciKSET452652:GJFD-4653-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054Imported.

Entry informationi

Entry nameiE4NG02_KITSK
AccessioniPrimary (citable) accession number: E4NG02
Entry historyi
Integrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: February 4, 2015
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.