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E4NB60 (E4NB60_KITSK) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 20. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length464 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation By similarity. RuleBase RU003914

Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase By similarity. HAMAP-Rule MF_00303

Catalytic activity

Peptidylproline (omega=180) = peptidylproline (omega=0). HAMAP-Rule MF_00303

Subcellular location

Cytoplasm. Note: About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm By similarity. HAMAP-Rule MF_00303

Domain

Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own By similarity. HAMAP-Rule MF_00303

Sequence similarities

Belongs to the FKBP-type PPIase family. Tig subfamily. HAMAP-Rule MF_00303 RuleBase RU003914

Contains 1 PPIase FKBP-type domain. HAMAP-Rule MF_00303

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain166 – 25186PPIase FKBP-type By similarity HAMAP-Rule MF_00303

Sequences

Sequence LengthMass (Da)Tools
E4NB60 [UniParc].

Last modified February 8, 2011. Version 1.
Checksum: 8DB6C0D9F64027DE

FASTA46450,794
        10         20         30         40         50         60 
MKSAVETLNP TRVRLIVEVP FEELKPSLDA AYKKINQQVT VPGFRKGKIP NKVIDQRFGR 

        70         80         90        100        110        120 
GAVLEEAVND ALPRFYTQAV DEGQIDVLGQ PDITEIEGVE NLADGGDLKF TAEVDVRPEV 

       130        140        150        160        170        180 
TLPEFAEIAV VVDPIEVSDE DVEKSLEQLR ERFASVKDVE RAATENDIVV IDLEAKVDGE 

       190        200        210        220        230        240 
VPEDGTATGV SYEIGSGRLL DGIDEAVVGL SAGESKTFTT TLKGGTQVGK DSEVTVTVTA 

       250        260        270        280        290        300 
VQEKELPELD DEFAQLASEF DTLEELRADS VKRLERMKEF DQATQAQEKV LDELLSRVEL 

       310        320        330        340        350        360 
DYPEKLLADE IGTRKHNLEH HQLEPMGLTL DTYLASQDKS HEDYEKETEE QAKKGIKTQF 

       370        380        390        400        410        420 
VLDQIVKNEE LGVNQEELTE HLIRRAAGSG LTPDQFAQQV VQGGQVQLLV GEVARGKALA 

       430        440        450        460 
LVVEAAKVTD TNGETVSFED EEETTEAAGT TDAAAEATEE SAEA 

« Hide

References

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP010968 Genomic DNA. Translation: BAJ28441.1.
RefSeqYP_004904397.1. NC_016109.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAJ28441; BAJ28441; KSE_26290.
GeneID11351189.
KEGGksk:KSE_26290.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK03545.

Enzyme and pathway databases

BioCycKSET452652:GJFD-2613-MONOMER.

Family and domain databases

Gene3D1.10.3120.10. 1 hit.
3.30.70.1050. 1 hit.
HAMAPMF_00303. Trigger_factor_Tig.
InterProIPR001179. PPIase_FKBP_dom.
IPR005215. Trig_fac.
IPR008880. Trigger_fac_C.
IPR008881. Trigger_fac_ribosome-bd_bac.
IPR027304. Trigger_fact/SurA_dom.
[Graphical view]
PfamPF00254. FKBP_C. 1 hit.
PF05698. Trigger_C. 1 hit.
PF05697. Trigger_N. 1 hit.
[Graphical view]
PIRSFPIRSF003095. Trigger_factor. 1 hit.
SUPFAMSSF102735. SSF102735. 1 hit.
SSF109998. SSF109998. 1 hit.
TIGRFAMsTIGR00115. tig. 1 hit.
PROSITEPS50059. FKBP_PPIASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameE4NB60_KITSK
AccessionPrimary (citable) accession number: E4NB60
Entry history
Integrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: April 16, 2014
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)