E3WH18 (E3WH18_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Estrogen receptor alpha EMBL BAJ41265.1

Gene names

Name:

ESR1 EMBL BAJ41265.1

Organism

Homo sapiens (Human) EMBL BAJ41265.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	190 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Molecular function	Receptor EMBL BAJ41265.1
Gene Ontology (GO)
Biological_process	androgen metabolic process Inferred from electronic annotation. Source: Compara antral ovarian follicle growth Inferred from electronic annotation. Source: Compara cellular response to estrogen stimulus Inferred from electronic annotation. Source: Compara epithelial cell development Inferred from electronic annotation. Source: Compara epithelial cell proliferation involved in mammary gland duct elongation Inferred from electronic annotation. Source: Compara intracellular receptor mediated signaling pathway Inferred from electronic annotation. Source: GOC male gonad development Inferred from electronic annotation. Source: Compara mammary gland alveolus development Inferred from electronic annotation. Source: Compara mammary gland branching involved in pregnancy Inferred from electronic annotation. Source: Compara positive regulation of fibroblast proliferation Inferred from electronic annotation. Source: Compara positive regulation of transcription from RNA polymerase II promoter Inferred from electronic annotation. Source: Compara prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis Inferred from electronic annotation. Source: Compara prostate epithelial cord elongation Inferred from electronic annotation. Source: Compara regulation of apoptotic process Inferred from electronic annotation. Source: Compara regulation of branching involved in prostate gland morphogenesis Inferred from electronic annotation. Source: Compara uterus development Inferred from electronic annotation. Source: Compara vagina development Inferred from electronic annotation. Source: Compara
Cellular_component	cytoplasm Inferred from electronic annotation. Source: Compara nucleus Inferred from electronic annotation. Source: Compara
Molecular_function	DNA binding Inferred from electronic annotation. Source: InterPro chromatin binding Inferred from electronic annotation. Source: Compara estrogen receptor activity Inferred from electronic annotation. Source: InterPro ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity Inferred from electronic annotation. Source: Compara steroid binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	190	1	EMBL BAJ41265.1

Sequences

	Sequence		Length	Mass (Da)
	E3WH18 [UniParc]. Last modified February 8, 2011. Version 1. Checksum: 93EC201CECE902B7	FASTA	190	20,511
	10 20 30 40 50 60 MTLHTKASGM ALLHQIQGNE LEPLNRPQLK IPLERPLGEV YLDSSKPAVY NYPEGAAYEF 70 80 90 100 110 120 NAAAAANAQV YGQTGLPYGP GSEAAAFGSN GLGGFPPLNS VSPSPLMLLH PPPQLSPFLQ 130 140 150 160 170 180 PHGQQVPYYL ENEPSGYTVR EAGPPAFYRP NSDNRRQGGR ERLASTNDKG SMAMESAKET 190 RYCAVCNDYA

References

[1]	"Identification of novel splicing events and post-transcriptional regulation of human estrogen receptor ? F isoforms." Kobayashi M., Ishii H., Sakuma Y. Mol. Cell. Endocrinol. 333:55-61(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Tissue: Ovary EMBL BAJ41265.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB588629 mRNA. Translation: BAJ41265.1.
IPI	IPI00218352.
UniGene	Hs.208124.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Gene expression databases
ArrayExpress	E3WH18.
Bgee	E3WH18.
Family and domain databases
InterPro	IPR001292. Oestr_rcpt. [Graphical view]
Pfam	PF02159. Oest_recep. 1 hit. [Graphical view]
PRINTS	PR00543. OESTROGENR.
ProtoNet	Search...
Other
ChiTaRS	ESR1. human.
NextBio	35497344.

Entry information

Entry name

E3WH18_HUMAN

Accession

Primary (citable) accession number: E3WH18

Entry history

Integrated into UniProtKB/TrEMBL:	February 8, 2011
Last sequence update:	February 8, 2011
Last modified:	April 3, 2013
This is version 12 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.