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Protein

General transcription factor IIF subunit 2

Gene

T2FB

Organism
Ictalurus punctatus (Channel catfish) (Silurus punctatus)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity.UniRule annotation

Catalytic activityi

ATP + H2O = ADP + phosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotation, HelicaseUniRule annotation, Hydrolase
Biological processTranscription, Transcription regulationUniRule annotation
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
General transcription factor IIF subunit 2UniRule annotation (EC:3.6.4.12UniRule annotation)
Alternative name(s):
Transcription initiation factor IIF subunit betaUniRule annotation
Gene namesi
Name:T2FBImported
Synonyms:GTF2F2Imported, t2fbImported
OrganismiIctalurus punctatus (Channel catfish) (Silurus punctatus)Imported
Taxonomic identifieri7998 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiSiluriformesIctaluridaeIctalurus
Proteomesi
  • UP000221080 Componenti: Genome assembly

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusUniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the TFIIF beta subunit family.UniRule annotation

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiView protein in InterPro
IPR003196. TFIIF_beta.
IPR011039. TFIIF_interaction.
IPR036388. WH-like_DNA-bd_sf.
IPR036390. WH_DNA-bd_sf.
PANTHERiPTHR10445. PTHR10445. 1 hit.
PfamiView protein in Pfam
PF02270. TFIIF_beta. 1 hit.
PIRSFiPIRSF015849. TFIIF-beta. 1 hit.
SUPFAMiSSF46785. SSF46785. 1 hit.
SSF50916. SSF50916. 1 hit.

Sequencei

Sequence statusi: Complete.

E3TEJ2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDRGDVDLT GAKQNTGVWL VKVPKYLSQQ WAKAPGRGEV GKLRIGKNQG
60 70 80 90 100
KAEVSFTLNE DLTMIESMGE KVSMVRAPRE HPFTLQTVGG QTLAVFTETS
110 120 130 140 150
SGQSDAEGSS SGTATGPDKI ALEGLVVQRA ECRAAANEHY MRLKRLQIEE
160 170 180 190 200
SSKPHRFSQQ LDKAVTTNYK PVANHAYNLD YEKKKKEEGK RARADRQQVL
210 220 230 240 250
DMLFSAFEKH QYYNIKDLVD ITKQPVIYLK EILRDIGIYN VKGTHKNTWE
260
LKPEYRHYQN EEKSD
Length:265
Mass (Da):30,036
Last modified:January 11, 2011 - v1
Checksum:iE35A55F3D901907B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GU588774 mRNA. Translation: ADO28728.1.
RefSeqiNP_001187504.1. NM_001200575.1.
UniGeneiIpu.8258.

Genome annotation databases

GeneIDi100528305.

Similar proteinsi

Entry informationi

Entry nameiE3TEJ2_ICTPU
AccessioniPrimary (citable) accession number: E3TEJ2
Entry historyiIntegrated into UniProtKB/TrEMBL: January 11, 2011
Last sequence update: January 11, 2011
Last modified: December 20, 2017
This is version 25 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported