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Protein

Protein-L-isoaspartate O-methyltransferase

Gene

PIMT

Organism
Ictalurus punctatus (Channel catfish) (Silurus punctatus)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

S-adenosyl-L-methionine + protein L-isoaspartate = S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionMethyltransferaseUniRule annotationImported, Transferase
LigandS-adenosyl-L-methionineUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Protein-L-isoaspartate O-methyltransferaseUniRule annotation (EC:2.1.1.77UniRule annotation)
Gene namesi
Name:PIMTImported
OrganismiIctalurus punctatus (Channel catfish) (Silurus punctatus)Imported
Taxonomic identifieri7998 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiSiluriformesIctaluridaeIctalurus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_500318230924 – 249Protein-L-isoaspartate O-methyltransferaseSequence analysisAdd BLAST226

Structurei

3D structure databases

ProteinModelPortaliE3TDU0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Family and domain databases

InterProiView protein in InterPro
IPR000682. PCMT.
IPR029063. SAM-dependent_MTases.
PANTHERiPTHR11579. PTHR11579. 1 hit.
SUPFAMiSSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00080. pimt. 1 hit.
PROSITEiView protein in PROSITE
PS01279. PCMT. 1 hit.

Sequencei

Sequence statusi: Complete.

E3TDU0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWCVARLAAL AFPMGLLLTR TMAWISSGKT HPQLISRLRE HGVIRSDRVF
60 70 80 90 100
EAMLATDRGI YSKDYPYEDS PQSIGYKATI SAPHMHAHVL EILSEQLTEG
110 120 130 140 150
ASALDVGSGS GYLTACFARM VGPTGKVVGI DHIAELVQAS VKNVQADELE
160 170 180 190 200
LLTSGRVKLV VGDGRLGFPD GAPYDAIHVG AAAPTIPKAL LDQLKPGGRL
210 220 230 240
VLPVGPEGGS QVLEQYDRQS DGTFVKKALM GVVYVPLTDR HHQWPGGEL
Length:249
Mass (Da):26,749
Last modified:January 11, 2011 - v1
Checksum:iBBCC3F8C4405ADFA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GU588520 mRNA. Translation: ADO28476.1.
RefSeqiNP_001188104.1. NM_001201175.1.
XP_017330784.1. XM_017475295.1.
UniGeneiIpu.2759.

Genome annotation databases

GeneIDi100528905.

Similar proteinsi

Entry informationi

Entry nameiE3TDU0_ICTPU
AccessioniPrimary (citable) accession number: E3TDU0
Entry historyiIntegrated into UniProtKB/TrEMBL: January 11, 2011
Last sequence update: January 11, 2011
Last modified: September 27, 2017
This is version 23 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)