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E3SXU4 (BHLHW_PEA) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 15. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Web links·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Basic helix-loop-helix protein A
Gene names
Name:BHLH
OrganismPisum sativum (Garden pea)
Taxonomic identifier3888 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaeFabeaePisum

Protein attributes

Sequence length652 AA.
Sequence statusComplete.
Protein existencePredicted

General annotation (Comments)

Function

Transcription activator involved in the control of flavonoid pigmentation. Ref.1

Subcellular location

Nucleus Probable.

Miscellaneous

Correspond to one of the seven genes studied by Gregor Mendel in 1866. The white flowered cv. Cameor (a allele) has a truncated non-functional BHLH protein (AC E3SXU5) due to a point mutation resulting in a mis-spliced transcript (Ref.1).

Sequence similarities

Contains 1 bHLH (basic helix-loop-helix) domain.

Ontologies

Keywords
   Biological processFlavonoid biosynthesis
Transcription
Transcription regulation
   Cellular componentNucleus
   Molecular functionActivator
Gene Ontology (GO)
   Biological_processflavonoid biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

regulation of transcription, DNA-templated

Inferred from electronic annotation. Source: UniProtKB-KW

transcription, DNA-templated

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentnucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 652652Basic helix-loop-helix protein A
PRO_0000425240

Regions

Domain464 – 51350bHLH
Compositional bias241 – 25414Asp-rich
Compositional bias405 – 4117Poly-Pro

Sequences

Sequence LengthMass (Da)Tools
E3SXU4 [UniParc].

Last modified January 11, 2011. Version 1.
Checksum: 8BB3995E981EFB73

FASTA65272,966
        10         20         30         40         50         60 
MTAPTPENGC NKLQNMLQAA VQSVQWTYSL FWQICPQQLI LVWGDGYYNG AIKTRKTVQP 

        70         80         90        100        110        120 
MEVSAEEASL QRSQQLRELY ESLSAGETNP PTRRPCASLS PEDLTESEWF YLMCVSFSFP 

       130        140        150        160        170        180 
PGVGLPGKAY ARRQHVWLTG ANEVDSKTFS RAILAKSANI QTVVCIPVLD GVVEIGTTDK 

       190        200        210        220        230        240 
IQEDLNFIKH VRSFFIDHHS LPPKPALSEH STSNPTYSTD HIPAIMYTVA DPASTAIPNQ 

       250        260        270        280        290        300 
DDMDEDEEED DEDDEVESGS EDETNQGHNQ HATSIIEAAE PSELMQIEMP DDIRIGSPND 

       310        320        330        340        350        360 
GSNNLDSDFH LLAVSNQGNP SRQIDSYTTE RWGPIEEPLD DSLQIQLSSS VLHHPLEDLT 

       370        380        390        400        410        420 
QEDTHYSQTV TTILQNQWID SPSINYINYS TQSSFTTWTN HHFHPPPPPD PATSQWLVKY 

       430        440        450        460        470        480 
ILFTVPYLHT KNHDETSPQT RDTAGVNSND PSARLRGKGT PQDELSANHV LAERRRREKL 

       490        500        510        520        530        540 
NERFIILRSL VPFVTKMDKA SILGDTIEYL KQLRRKIQDL ETRNRQMESE KSGVTVLVGP 

       550        560        570        580        590        600 
TEKKKVRIVE GNGTGGGVRA KAVEVVASVQ VSIIESDALL EIECLQREGL LLDVMMMLRE 

       610        620        630        640        650 
LRIEVIGVQS SLNNGVFVAE LRAKVKENGN GKKVSIVEVK RALNQIIPHN NI 

« Hide

References

Web resources

Protein Spotlight

On the garden pea - Issue 159 of April 2014

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
GU132941 Genomic DNA. Translation: ADO13282.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D4.10.280.10. 1 hit.
InterProIPR011598. bHLH_dom.
IPR025610. MYC/MYB_N.
[Graphical view]
PfamPF14215. bHLH-MYC_N. 1 hit.
PF00010. HLH. 1 hit.
[Graphical view]
SMARTSM00353. HLH. 1 hit.
[Graphical view]
SUPFAMSSF47459. SSF47459. 1 hit.
PROSITEPS50888. BHLH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameBHLHW_PEA
AccessionPrimary (citable) accession number: E3SXU4
Entry history
Integrated into UniProtKB/Swiss-Prot: February 19, 2014
Last sequence update: January 11, 2011
Last modified: May 14, 2014
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Protein Spotlight

Protein Spotlight articles and cited UniProtKB/Swiss-Prot entries