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E3SXU4

- BHLHW_PEA

UniProt

E3SXU4 - BHLHW_PEA

Protein

Basic helix-loop-helix protein A

Gene

BHLH

Organism
Pisum sativum (Garden pea)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 16 (01 Oct 2014)
      Sequence version 1 (11 Jan 2011)
      Previous versions | rss
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    Functioni

    Transcription activator involved in the control of flavonoid pigmentation.1 Publication

    GO - Biological processi

    1. flavonoid biosynthetic process Source: UniProtKB-KW
    2. regulation of transcription, DNA-templated Source: UniProtKB-KW
    3. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Molecular functioni

    Activator

    Keywords - Biological processi

    Flavonoid biosynthesis, Transcription, Transcription regulation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Basic helix-loop-helix protein A
    Gene namesi
    Name:BHLH
    OrganismiPisum sativum (Garden pea)
    Taxonomic identifieri3888 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaeFabeaePisum

    Subcellular locationi

    Nucleus Curated

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 652652Basic helix-loop-helix protein APRO_0000425240Add
    BLAST

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini464 – 51350bHLHPROSITE-ProRule annotationAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi241 – 25414Asp-richAdd
    BLAST
    Compositional biasi405 – 4117Poly-Pro

    Sequence similaritiesi

    Contains 1 bHLH (basic helix-loop-helix) domain.PROSITE-ProRule annotation

    Family and domain databases

    Gene3Di4.10.280.10. 1 hit.
    InterProiIPR011598. bHLH_dom.
    IPR025610. MYC/MYB_N.
    [Graphical view]
    PfamiPF14215. bHLH-MYC_N. 1 hit.
    PF00010. HLH. 1 hit.
    [Graphical view]
    SMARTiSM00353. HLH. 1 hit.
    [Graphical view]
    SUPFAMiSSF47459. SSF47459. 1 hit.
    PROSITEiPS50888. BHLH. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E3SXU4-1 [UniParc]FASTAAdd to Basket

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    MTAPTPENGC NKLQNMLQAA VQSVQWTYSL FWQICPQQLI LVWGDGYYNG    50
    AIKTRKTVQP MEVSAEEASL QRSQQLRELY ESLSAGETNP PTRRPCASLS 100
    PEDLTESEWF YLMCVSFSFP PGVGLPGKAY ARRQHVWLTG ANEVDSKTFS 150
    RAILAKSANI QTVVCIPVLD GVVEIGTTDK IQEDLNFIKH VRSFFIDHHS 200
    LPPKPALSEH STSNPTYSTD HIPAIMYTVA DPASTAIPNQ DDMDEDEEED 250
    DEDDEVESGS EDETNQGHNQ HATSIIEAAE PSELMQIEMP DDIRIGSPND 300
    GSNNLDSDFH LLAVSNQGNP SRQIDSYTTE RWGPIEEPLD DSLQIQLSSS 350
    VLHHPLEDLT QEDTHYSQTV TTILQNQWID SPSINYINYS TQSSFTTWTN 400
    HHFHPPPPPD PATSQWLVKY ILFTVPYLHT KNHDETSPQT RDTAGVNSND 450
    PSARLRGKGT PQDELSANHV LAERRRREKL NERFIILRSL VPFVTKMDKA 500
    SILGDTIEYL KQLRRKIQDL ETRNRQMESE KSGVTVLVGP TEKKKVRIVE 550
    GNGTGGGVRA KAVEVVASVQ VSIIESDALL EIECLQREGL LLDVMMMLRE 600
    LRIEVIGVQS SLNNGVFVAE LRAKVKENGN GKKVSIVEVK RALNQIIPHN 650
    NI 652
    Length:652
    Mass (Da):72,966
    Last modified:January 11, 2011 - v1
    Checksum:i8BB3995E981EFB73
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    GU132941 Genomic DNA. Translation: ADO13282.1.

    Cross-referencesi

    Web resourcesi

    Protein Spotlight

    On the garden pea - Issue 159 of April 2014

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    GU132941 Genomic DNA. Translation: ADO13282.1 .

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 4.10.280.10. 1 hit.
    InterProi IPR011598. bHLH_dom.
    IPR025610. MYC/MYB_N.
    [Graphical view ]
    Pfami PF14215. bHLH-MYC_N. 1 hit.
    PF00010. HLH. 1 hit.
    [Graphical view ]
    SMARTi SM00353. HLH. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47459. SSF47459. 1 hit.
    PROSITEi PS50888. BHLH. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION.

    Entry informationi

    Entry nameiBHLHW_PEA
    AccessioniPrimary (citable) accession number: E3SXU4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 19, 2014
    Last sequence update: January 11, 2011
    Last modified: October 1, 2014
    This is version 16 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Correspond to one of the seven genes studied by Gregor Mendel in 1866. The white flowered cv. Cameor (a allele) has a truncated non-functional BHLH protein (AC E3SXU5) due to a point mutation resulting in a mis-spliced transcript (PubMed:20949001).1 Publication

    Documents

    1. Protein Spotlight
      Protein Spotlight articles and cited UniProtKB/Swiss-Prot entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3