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E3S9K3 (DAPB_PYRTT) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 17. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable dipeptidyl-aminopeptidase B

Short name=DPAP B
EC=3.4.14.5
Gene names
Name:dapB
ORF Names:PTT_19734
OrganismPyrenophora teres f. teres (strain 0-1) (Barley net blotch fungus) (Drechslera teres f. teres) [Complete proteome]
Taxonomic identifier861557 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaDothideomycetesPleosporomycetidaePleosporalesPleosporineaePleosporaceaePyrenophora

Protein attributes

Sequence length907 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Type IV dipeptidyl-peptidase which removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline By similarity.

Catalytic activity

Release of an N-terminal dipeptide, Xaa-Yaa-|-Zaa-, from a polypeptide, preferentially when Yaa is Pro, provided Zaa is neither Pro nor hydroxyproline.

Subcellular location

Vacuole membrane; Single-pass type II membrane protein By similarity. Note: Lysosome-like vacuoles By similarity.

Sequence similarities

Belongs to the peptidase S9B family.

Ontologies

Keywords
   Cellular componentMembrane
Vacuole
   DomainSignal-anchor
Transmembrane
Transmembrane helix
   Molecular functionAminopeptidase
Hydrolase
Protease
Serine protease
   PTMGlycoprotein
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processproteolysis

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

vacuolar membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionaminopeptidase activity

Inferred from electronic annotation. Source: UniProtKB-KW

serine-type peptidase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 907907Probable dipeptidyl-aminopeptidase B
PRO_0000412161

Regions

Topological domain1 – 9393Cytoplasmic Potential
Transmembrane94 – 11421Helical; Signal-anchor for type II membrane protein; Potential
Topological domain115 – 907793Vacuolar Potential

Sites

Active site7511Charge relay system By similarity
Active site8281Charge relay system By similarity
Active site8611Charge relay system By similarity

Amino acid modifications

Glycosylation5601N-linked (GlcNAc...) Potential
Glycosylation8051N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
E3S9K3 [UniParc].

Last modified January 11, 2011. Version 1.
Checksum: 6A5E656B4F204015

FASTA907102,862
        10         20         30         40         50         60 
MPRQRAPKEE EAELLTKQER STRSSEDASD ASVSSISTTS LVLEHINNPA INGTSRSRRG 

        70         80         90        100        110        120 
EKYTDEDDEA QEAFDVEDGR YKAPVAVDKK TRRWLWIVGI ACVTGWALAL VFFLMSGSYK 

       130        140        150        160        170        180 
HVSTRPHDPL ASSTKGSGKK ITMDDVFGGS FYAQQQSVKW IAGPNGEDGL LLEKNTGNAG 

       190        200        210        220        230        240 
YLVVEDIRNK GDGDSSAKKT KLMQKSSFDV DGKLVRPNEV WPSKDFKKVL VQSDFEKNWR 

       250        260        270        280        290        300 
HSGTGKYWIF DVATQTGEPL DPENQDGRVQ LASLSPQSDA VVFTRDNNMY LRKLDSKEVI 

       310        320        330        340        350        360 
QITRDGGSEL FYGIPDWVYE EEVFQGNSAT WWSEDGKYIA FLRTDESTVP TYPVQYFVSR 

       370        380        390        400        410        420 
PSGNKPKAGE ENYPEVRNIK YPKAGAPNPI VALQFYDVEK AEVFSVEIED DFRDNNRLIT 

       430        440        450        460        470        480 
EIVWAGKTKQ VLVRETNRES DILKVVLMDV EKRTGKTVRT ENVAELDGGW FEVSQKTTFV 

       490        500        510        520        530        540 
PADPDNGRKD DGYIDTIIHE GYDHIGYFTP LDNDKPVLLS QGEWEVVDAP SRVDLKNNMV 

       550        560        570        580        590        600 
YYVSTEKSSM ERHAYSVFLN GTGTSEVVEN SGSGYYEASF SAGGSYALIT YQGPGIPWQK 

       610        620        630        640        650        660 
IISTPSNKDK FEKVLEENKH LDRFVREREM PILNYQTIDV DGFKLNVLER RPPHFNEKKK 

       670        680        690        700        710        720 
YPVLFYQYSG PNSQEVNKKF HVDFQAYVAA NLGYIVVTVD GRGTGFLGRK LRCITRGNLG 

       730        740        750        760        770        780 
YYEAHDQIAA AKIWASKKYV DADRLAIWGW SFGGFNTLKT LEQDGGQTFK YGMAVAPVTD 

       790        800        810        820        830        840 
WRYYDSIYTE RFMHMPQNNA AGYDNSTITD VASLAKNTRF LIMHGVADDN VHMQNTLTLL 

       850        860        870        880        890        900 
DRLDLAGVEN YDVHVFPDSD HSIYFHNANR IVYDKLRWWL INAFNGEWAK IKTAEPKSQV 


DARLERR 

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References

[1]"A first genome assembly of the barley fungal pathogen Pyrenophora teres f. teres."
Ellwood S.R., Liu Z., Syme R.A., Lai Z., Hane J.K., Keiper F., Moffat C.S., Oliver R.P., Friesen T.L.
Genome Biol. 11:R109.1-R109.14(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 0-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
GL537929 Genomic DNA. Translation: EFQ85356.1.
RefSeqXP_003306558.1. XM_003306510.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiEFQ85356; EFQ85356; PTT_19734.
GeneID10512411.
KEGGpte:PTT_19734.

Phylogenomic databases

KOK01282.
OrthoDBEOG72VHFG.

Family and domain databases

Gene3D2.140.10.30. 1 hit.
InterProIPR001375. Peptidase_S9.
IPR002469. Peptidase_S9B.
[Graphical view]
PfamPF00930. DPPIV_N. 1 hit.
PF00326. Peptidase_S9. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDAPB_PYRTT
AccessionPrimary (citable) accession number: E3S9K3
Entry history
Integrated into UniProtKB/Swiss-Prot: July 27, 2011
Last sequence update: January 11, 2011
Last modified: April 16, 2014
This is version 17 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Peptidase families

Classification of peptidase families and list of entries