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E3QQU9 (LAP1_COLGM) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 12. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Leucine aminopeptidase 1

EC=3.4.11.-
Alternative name(s):
Leucyl aminopeptidase 1
Short name=LAP1
Gene names
Name:LAP1
ORF Names:GLRG_08381
OrganismColletotrichum graminicola (strain M1.001 / M2 / FGSC 10212) (Maize anthracnose fungus) (Glomerella graminicola) [Complete proteome]
Taxonomic identifier645133 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesHypocreomycetidaeGlomerellalesGlomerellaceaemitosporic GlomerellaceaeColletotrichum

Protein attributes

Sequence length401 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Extracellular aminopeptidase that allows assimilation of proteinaceous substrates By similarity.

Catalytic activity

Release of an N-terminal amino acid from a peptide.

Cofactor

Binds 2 zinc ions per subunit By similarity.

Subunit structure

Monomer By similarity.

Subcellular location

Secreted By similarity.

Sequence similarities

Belongs to the peptidase M28 family. M28E subfamily.

Ontologies

Keywords
   Cellular componentSecreted
   DomainSignal
   LigandMetal-binding
Zinc
   Molecular functionAminopeptidase
Hydrolase
Protease
   PTMDisulfide bond
Glycoprotein
Zymogen
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processproteolysis

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionaminopeptidase activity

Inferred from electronic annotation. Source: UniProtKB-KW

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1818 Potential
Propeptide19 – 8769 By similarity
PRO_0000412405
Chain88 – 401314Leucine aminopeptidase 1
PRO_0000412406

Sites

Metal binding1871Zinc 1 By similarity
Metal binding2061Zinc 1 By similarity
Metal binding2061Zinc 2; catalytic By similarity
Metal binding2451Zinc 2; catalytic By similarity
Metal binding2721Zinc 1 By similarity
Metal binding3541Zinc 2; catalytic By similarity

Amino acid modifications

Glycosylation1791N-linked (GlcNAc...) Potential
Disulfide bond321 ↔ 325 By similarity

Sequences

Sequence LengthMass (Da)Tools
E3QQU9 [UniParc].

Last modified January 11, 2011. Version 1.
Checksum: 2868A43AE5F44660

FASTA40144,812
        10         20         30         40         50         60 
MKVAKASLLT ILAHSVSARF LAEDEINRVQ LYPAGSEPEK YLIELAPGDT RWVTEEEKWE 

        70         80         90        100        110        120 
LRRNGNRFFD ITDHKDLGAT RLRTKTKSVF PEKCSLQDKV KPLLKDLDKS EIQKNLEKFT 

       130        140        150        160        170        180 
SFHTRYYKSD YGRQSSEWLL AKIDSIIKDA GADKNVYAQP FPHTWQQSSI IVTIPGKSNS 

       190        200        210        220        230        240 
TVIIGAHQDS INLWLPSILA APGADDDGSG SMTILEAFRT LLKSKDIVSG KADNTIEFHW 

       250        260        270        280        290        300 
YSAEEGGLLG SQAIFSSYEK EGRDIKAMLQ QDMTGFVQRT LDAGQPESVG VITDFVDPGL 

       310        320        330        340        350        360 
TGFIKKVIVE YCKVPYVETK CGYACSDHAS ASKAGYPSAF VIESAFEYSD NHIHSVDDTI 

       370        380        390        400 
KYLSFDHMLE HAKMTLGLVY ELGFTDFTAL EKKGESVSEE L 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
GG697368 Genomic DNA. Translation: EFQ33237.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein family/group databases

MEROPSM28.006.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiEFQ33237; EFQ33237; GLRG_08381.

Phylogenomic databases

OrthoDBEOG7GQZ51.

Family and domain databases

InterProIPR007484. Peptidase_M28.
[Graphical view]
PfamPF04389. Peptidase_M28. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameLAP1_COLGM
AccessionPrimary (citable) accession number: E3QQU9
Entry history
Integrated into UniProtKB/Swiss-Prot: September 21, 2011
Last sequence update: January 11, 2011
Last modified: March 19, 2014
This is version 12 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Peptidase families

Classification of peptidase families and list of entries