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E3QKD2

- DAPB_COLGM

UniProt

E3QKD2 - DAPB_COLGM

Protein

Probable dipeptidyl-aminopeptidase B

Gene

DAPB

Organism
Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212) (Maize anthracnose fungus) (Glomerella graminicola)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 19 (01 Oct 2014)
      Sequence version 1 (11 Jan 2011)
      Previous versions | rss
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    Functioni

    Type IV dipeptidyl-peptidase which removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.By similarity

    Catalytic activityi

    Release of an N-terminal dipeptide, Xaa-Yaa-|-Zaa-, from a polypeptide, preferentially when Yaa is Pro, provided Zaa is neither Pro nor hydroxyproline.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei768 – 7681Charge relay systemBy similarity
    Active sitei845 – 8451Charge relay systemBy similarity
    Active sitei878 – 8781Charge relay systemBy similarity

    GO - Molecular functioni

    1. aminopeptidase activity Source: UniProtKB-KW
    2. serine-type peptidase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Aminopeptidase, Hydrolase, Protease, Serine protease

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable dipeptidyl-aminopeptidase B (EC:3.4.14.5)
    Short name:
    DPAP B
    Gene namesi
    Name:DAPB
    ORF Names:GLRG_06464
    OrganismiColletotrichum graminicola (strain M1.001 / M2 / FGSC 10212) (Maize anthracnose fungus) (Glomerella graminicola)
    Taxonomic identifieri645133 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesHypocreomycetidaeGlomerellalesGlomerellaceaemitosporic GlomerellaceaeColletotrichum
    ProteomesiUP000008782: Unassembled WGS sequence

    Subcellular locationi

    Vacuole membrane By similarity; Single-pass type II membrane protein By similarity
    Note: Lysosome-like vacuoles.By similarity

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. vacuolar membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Membrane, Vacuole

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 921921Probable dipeptidyl-aminopeptidase BPRO_0000412144Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi131 – 1311N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi364 – 3641N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi577 – 5771N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi827 – 8271N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Structurei

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini1 – 108108CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini130 – 921792VacuolarSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei109 – 12921Helical; Signal-anchor for type II membrane proteinSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi64 – 8320Asp-richAdd
    BLAST

    Sequence similaritiesi

    Belongs to the peptidase S9B family.Curated

    Keywords - Domaini

    Signal-anchor, Transmembrane, Transmembrane helix

    Phylogenomic databases

    OrthoDBiEOG72VHFG.

    Family and domain databases

    Gene3Di2.140.10.30. 1 hit.
    3.40.50.1820. 1 hit.
    InterProiIPR029058. AB_hydrolase.
    IPR001375. Peptidase_S9.
    IPR002469. Peptidase_S9B.
    [Graphical view]
    PfamiPF00930. DPPIV_N. 1 hit.
    PF00326. Peptidase_S9. 1 hit.
    [Graphical view]
    SUPFAMiSSF53474. SSF53474. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    E3QKD2-1 [UniParc]FASTAAdd to Basket

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    MDAPATASRQ PIAEEPRMSQ ESSLSTVSTT SLVFDRLHEH NEKSYHSSSQ    50
    RRRAPSASRG GYADHPDDDD DDDESYKEAD TNDLETGPFL APASVMMRRV 100
    GVDRGLKKVI LILAAAFLFA WGAALFVFLS NKSYKHASTI DHDPSATSRG 150
    SGKPVTLDQV ISGFWYPTSH SISWIEGPNG EDGLLLEQGA RGKDYLVVED 200
    VRSGNKDSQV SANVVQSRTL MKNPWINVGG RQLAPSDTRP SKDMKKVLVS 250
    TDRQRNWRYS YTALYWIFDV ETQTAEALDP EHPDGRVQLA TWSPQSNAIV 300
    FTRDNNLFLR KLDGDKKVTQ ITNDGGPEYF YGIPDWVYEE EVFATNSATW 350
    YSEDGKYVAF LRTNETGVPE YPLQYFLSRP SGKEKPPGEE TYPDEKRIKY 400
    PRAGSHNPVV DLLFFDVERG DVFSVDIDGG FADDDRLINM VLWANDKVLI 450
    KETNRVSDIM RVVLVDVVAR TGKTVNTIDV GELDGGWFEI SHTTQFIPAD 500
    PANGRPQDGY IDTVVHGNGD HIAYFSPMDN AEPVYLTGGD WEVDDGPSAV 550
    DLKNNLVYFV ATKESSIQRH VYSVHLNRSD LKPFTDTKFE SYYDISFSSG 600
    AGYALLSYQG PKIPWQKVVS TPSSPVSYEH VVEKNEDLAE NAKKYELPIL 650
    NYGTLKVDGV ELNYVERRPP HFDEKKKYPV LFQQYSGPGS QSVHKKFAVD 700
    FQSYVASALG YLVVTVDGRG TGFIGRKNRV LIRDHLGYWE AHDQIAAAQA 750
    WAAKKYVDPA RIAIWGWSYG GFNTLKTLEM DAGRTFSYGM AVAPVTDWRF 800
    YDSIYTERYM RTPQLNPSGY DQTAVSNVSA LAGNVRWLMM HGVGDDNVHY 850
    QNTLTLLDKL DLNGIENYDV HVFPDSDHGI YFHGANRIVY DKLSNWLINA 900
    FNGEWLKVAG AKPIVEPKAR V 921
    Length:921
    Mass (Da):103,378
    Last modified:January 11, 2011 - v1
    Checksum:i92129EF1EB01470B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    GG697354 Genomic DNA. Translation: EFQ31320.1.

    Genome annotation databases

    EnsemblFungiiEFQ31320; EFQ31320; GLRG_06464.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    GG697354 Genomic DNA. Translation: EFQ31320.1 .

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii EFQ31320 ; EFQ31320 ; GLRG_06464 .

    Phylogenomic databases

    OrthoDBi EOG72VHFG.

    Family and domain databases

    Gene3Di 2.140.10.30. 1 hit.
    3.40.50.1820. 1 hit.
    InterProi IPR029058. AB_hydrolase.
    IPR001375. Peptidase_S9.
    IPR002469. Peptidase_S9B.
    [Graphical view ]
    Pfami PF00930. DPPIV_N. 1 hit.
    PF00326. Peptidase_S9. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53474. SSF53474. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses."
      O'Connell R.J., Thon M.R., Hacquard S., Amyotte S.G., Kleemann J., Torres M.F., Damm U., Buiate E.A., Epstein L., Alkan N., Altmueller J., Alvarado-Balderrama L., Bauser C.A., Becker C., Birren B.W., Chen Z., Choi J., Crouch J.A.
      , Duvick J.P., Farman M.A., Gan P., Heiman D., Henrissat B., Howard R.J., Kabbage M., Koch C., Kracher B., Kubo Y., Law A.D., Lebrun M.-H., Lee Y.-H., Miyara I., Moore N., Neumann U., Nordstroem K., Panaccione D.G., Panstruga R., Place M., Proctor R.H., Prusky D., Rech G., Reinhardt R., Rollins J.A., Rounsley S., Schardl C.L., Schwartz D.C., Shenoy N., Shirasu K., Sikhakolli U.R., Stueber K., Sukno S.A., Sweigard J.A., Takano Y., Takahara H., Trail F., van der Does H.C., Voll L.M., Will I., Young S., Zeng Q., Zhang J., Zhou S., Dickman M.B., Schulze-Lefert P., Ver Loren van Themaat E., Ma L.-J., Vaillancourt L.J.
      Nat. Genet. 44:1060-1065(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: M1.001 / M2 / FGSC 10212.

    Entry informationi

    Entry nameiDAPB_COLGM
    AccessioniPrimary (citable) accession number: E3QKD2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 27, 2011
    Last sequence update: January 11, 2011
    Last modified: October 1, 2014
    This is version 19 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Peptidase families
      Classification of peptidase families and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3