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Protein

Elongation factor Tu

Gene

tufB

Organism
Acetoanaerobium sticklandii (strain ATCC 12662 / DSM 519 / JCM 1433 / NCIMB 10654) (Clostridium sticklandii)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi19 – 26GTPUniRule annotation8
Nucleotide bindingi82 – 86GTPUniRule annotation5
Nucleotide bindingi137 – 140GTPUniRule annotation4

GO - Molecular functioni

Keywordsi

Molecular functionElongation factorUniRule annotationImported
Biological processProtein biosynthesis
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TuUniRule annotation
Short name:
EF-TuUniRule annotation
Gene namesi
Name:tufBImported
Synonyms:tufUniRule annotation
Ordered Locus Names:CLOST_2206Imported, CLOST_2219Imported
OrganismiAcetoanaerobium sticklandii (strain ATCC 12662 / DSM 519 / JCM 1433 / NCIMB 10654) (Clostridium sticklandii)Imported
Taxonomic identifieri499177 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesPeptostreptococcaceaeAcetoanaerobium
Proteomesi
  • UP000007041 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi499177.CLOST_2219

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 206Tr-type GInterPro annotationAdd BLAST197

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili141 – 161Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG4105CGV Bacteria
COG0050 LUCA
HOGENOMiHOG000229290
KOiK02358
OMAiYGHIDCP
OrthoDBiPOG091H00LA

Family and domain databases

CDDicd03697 EFTU_II, 1 hit
HAMAPiMF_00118_B EF_Tu_B, 1 hit
InterProiView protein in InterPro
IPR004161 EFTu-like_2
IPR033720 EFTU_2
IPR031157 G_TR_CS
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd_dom
IPR000795 TF_GTP-bd_dom
IPR009000 Transl_B-barrel_sf
IPR009001 Transl_elong_EF1A/Init_IF2_C
IPR004541 Transl_elong_EFTu/EF1A_bac/org
IPR004160 Transl_elong_EFTu/EF1A_C
PfamiView protein in Pfam
PF00009 GTP_EFTU, 1 hit
PF03144 GTP_EFTU_D2, 1 hit
PF03143 GTP_EFTU_D3, 1 hit
PRINTSiPR00315 ELONGATNFCT
SUPFAMiSSF50447 SSF50447, 1 hit
SSF50465 SSF50465, 1 hit
SSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00485 EF-Tu, 1 hit
TIGR00231 small_GTP, 1 hit
PROSITEiView protein in PROSITE
PS00301 G_TR_1, 1 hit
PS51722 G_TR_2, 1 hit

Sequencei

Sequence statusi: Complete.

E3PTX2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKAKFERTK PHVNIGTIGH VDHGKTTLTA AITKTLHARY GFGAAVDFEN
60 70 80 90 100
IDKAPEERER GITISTAHVE YETPNRHYAH VDCPGHADYV KNMITGAAQM
110 120 130 140 150
DGAILVCSAA DGPMPQTREH ILLSRQVGVP YIVVFLNKCD MVDDEELLEL
160 170 180 190 200
VEMEVRDLLN EYEFPGDDTP IIRGSALKAL EDPASEWGDK IVELFEQIDS
210 220 230 240 250
YIPEPERDID KPFLMPVEDV FSITGRGTVA TGRVERGILK VQDEVEIVGL
260 270 280 290 300
TEEARKVVVT GVEMFRKLLD QAQAGDNIGA LLRGVTRDDI ERGQVLAKSG
310 320 330 340 350
TIKPRTKFTA EIYVLKKEEG GRHTPFFKGY RPQFYFRTTD VTGDITLPDG
360 370 380 390
VEMVMPGDNI TISVELITPI AMEEGLRFAI REGGRTVGAG VVATIVE
Length:397
Mass (Da):43,882
Last modified:January 11, 2011 - v1
Checksum:i77425217445FA464
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FP565809 Genomic DNA Translation: CBH22326.1
FP565809 Genomic DNA Translation: CBH22339.1
RefSeqiWP_013362418.1, NC_014614.1

Genome annotation databases

EnsemblBacteriaiCBH22326; CBH22326; CLOST_2206
CBH22339; CBH22339; CLOST_2219
GeneIDi35558591
KEGGicst:CLOST_2206
cst:CLOST_2219

Similar proteinsi

Entry informationi

Entry nameiE3PTX2_ACESD
AccessioniPrimary (citable) accession number: E3PTX2
Entry historyiIntegrated into UniProtKB/TrEMBL: January 11, 2011
Last sequence update: January 11, 2011
Last modified: March 28, 2018
This is version 49 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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