E3PTM8 (E3PTM8_CLOSD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Alanine racemase RuleBase RU000608
EC=5.1.1.1 RuleBase RU000608

Gene names

Ordered Locus Names:

CLOST_2112 EMBL CBH22232.1

Organism

Clostridium sticklandii (strain ATCC 12662 / DSM 519 / JCM 1433 / NCIB 10654) [Complete proteome] [HAMAP]

Taxonomic identifier

499177 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Clostridia › Clostridiales › Peptostreptococcaceae › Clostridium sticklandii

Protein attributes

Sequence length	384 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-alanine = D-alanine. RuleBase RU000608 SAAS SAAS020622
Cofactor	Pyridoxal phosphate By similarity. RuleBase RU000608 SAAS SAAS020622
Pathway	Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. SAAS SAAS020622 RuleBase RU004247
Sequence similarities	Belongs to the alanine racemase family. RuleBase RU004188

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU000608 SAAS SAAS020622
Molecular function	Isomerase SAAS SAAS020622 RuleBase RU000608 EMBL CBH22232.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	D-alanine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	alanine racemase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	E3PTM8 [UniParc]. Last modified January 11, 2011. Version 1. Checksum: 79CEDBB61FDEE6A2	FASTA	384	43,610
	10 20 30 40 50 60 MSHTFRPTWA EINLDHVKAN YNNIRKLLKP ETKFCAVIKA NAYGHGAVQY AKVLDKEGAD 70 80 90 100 110 120 YFAVAVCEEA LELRQNSITK PIMCLGYVPE DRFKDMMQNN VDITIYSYEK AALLSQIAKD 130 140 150 160 170 180 NNLNAKIHIK LDSGMSRLGL QCDNEAVDEI LKISTLENLE IVGIFTHFAL ADDKDLSYTH 190 200 210 220 230 240 EQYKNYSFVV NELETKGLKI PIKHVCNSAA TMMLPEYHLD MVRPGIILYG HYPSDDVDKS 250 260 270 280 290 300 KVKLYPAMAL KSTVAHVKKL EEGRGISYGH KYRSKENEII ATIPIGYADG FTRMLSGQAD 310 320 330 340 350 360 VKLNDKMVPV VGRICMDQCM LSLEEEAKVG DQITIFSDEE GMDIERFAQR LGTINYELLC 370 380 MVQRRVPRIY KEDGKIIKVQ DYLI

References

[1]

"Clostridium sticklandii, a specialist in amino acid degradation:revisiting its metabolism through its genome sequence." Fonknechten N., Chaussonnerie S., Tricot S., Lajus A., Andreesen J.R., Perchat N., Pelletier E., Gouyvenoux M., Barbe V., Salanoubat M., Le Paslier D., Weissenbach J., Cohen G.N., Kreimeyer A. BMC Genomics 11:555-555(2010) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 12662 / DSM 519 / JCM 1433 / NCIB 10654.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FP565809 Genomic DNA. Translation: CBH22232.1.
RefSeq	YP_003937137.1. NC_014614.1.
3D structure databases
ProteinModelPortal	E3PTM8.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CBH22232; CBH22232; CLOST_2112.
GeneID	9855333.
KEGG	cst:CLOST_2112.
PATRIC	42274857. VBICloSti32817_2100.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000031444.
KO	K01775.
Enzyme and pathway databases
BioCyc	CSTI499177:GJE9-2177-MONOMER.
UniPathway	UPA00042; UER00497.
Family and domain databases
Gene3D	2.40.37.10. 1 hit.
HAMAP	MF_01201. Ala_racemase.
InterPro	IPR000821. Ala_racemase. IPR009006. Ala_racemase/Decarboxylase_C. IPR011079. Ala_racemase_C. IPR001608. Ala_racemase_N. IPR020622. Ala_racemase_pyridoxalP-BS. [Graphical view]
Pfam	PF00842. Ala_racemase_C. 1 hit. PF01168. Ala_racemase_N. 1 hit. [Graphical view]
PRINTS	PR00992. ALARACEMASE.
SMART	SM01005. Ala_racemase_C. 1 hit. [Graphical view]
SUPFAM	SSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMs	TIGR00492. alr. 1 hit.
PROSITE	PS00395. ALANINE_RACEMASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

E3PTM8_CLOSD

Accession

Primary (citable) accession number: E3PTM8

Entry history

Integrated into UniProtKB/TrEMBL:	January 11, 2011
Last sequence update:	January 11, 2011
Last modified:	May 1, 2013
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)