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E3PS86

- E3PS86_CLOSD

UniProt

E3PS86 - E3PS86_CLOSD

Protein
Submitted name:

Glycine C-acetyltransferase

Gene

kbl

Organism
Clostridium sticklandii (strain ATCC 12662 / DSM 519 / JCM 1433 / NCIB 10654)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 22 (01 Oct 2014)
      Sequence version 1 (11 Jan 2011)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Pimeloyl-[acyl-carrier protein] + L-alanine = 8-amino-7-oxononanoate + CO2 + holo-[acyl-carrier protein].SAAS annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    GO - Molecular functioni

    1. 8-amino-7-oxononanoate synthase activity Source: InterPro
    2. glycine C-acetyltransferase activity Source: UniProtKB-EC
    3. pyridoxal phosphate binding Source: InterPro

    GO - Biological processi

    1. biotin biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    AcyltransferaseImported, Transferase

    Keywords - Biological processi

    Biotin biosynthesisSAAS annotation

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciCSTI499177:GJE9-1674-MONOMER.
    UniPathwayiUPA00078.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Glycine C-acetyltransferaseImported (EC:2.3.1.29Imported)
    Gene namesi
    Name:kblImported
    Ordered Locus Names:CLOST_1620Imported
    OrganismiClostridium sticklandii (strain ATCC 12662 / DSM 519 / JCM 1433 / NCIB 10654)Imported
    Taxonomic identifieri499177 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesPeptostreptococcaceaePeptoclostridium
    ProteomesiUP000007041: Chromosome

    Interactioni

    Subunit structurei

    Homodimer.SAAS annotation

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000221022.
    KOiK00639.
    OMAiFNCNAGT.

    Family and domain databases

    Gene3Di3.40.640.10. 1 hit.
    3.90.1150.10. 1 hit.
    InterProiIPR001917. Aminotrans_II_pyridoxalP_BS.
    IPR004839. Aminotransferase_I/II.
    IPR010962. AONS_Archaea/Firmicutes.
    IPR004723. AONS_Archaea/Proteobacteria.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    IPR015422. PyrdxlP-dep_Trfase_major_sub2.
    [Graphical view]
    PfamiPF00155. Aminotran_1_2. 1 hit.
    [Graphical view]
    SUPFAMiSSF53383. SSF53383. 1 hit.
    TIGRFAMsiTIGR00858. bioF. 1 hit.
    TIGR01825. gly_Cac_T_rel. 1 hit.
    PROSITEiPS00599. AA_TRANSFER_CLASS_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E3PS86-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSNIHEMGFI KEKIDELKQA GLYKEVVTLD GPNEAECSIN GKMAINLSSN    50
    NYLGFSNHPR LKKAAIEAIE KYGAGAGAVR PIIGNMKIHD ELEALLAVFK 100
    KEEAVLVFQS GFNCNAGTIQ AVTEAGDLIL SDELNHASII DGARLSKAKK 150
    ATYKHSDMAD LERVLKETRS EYNNVLIITD GVFSMDGDIA KLPEIVELAE 200
    KYNCMTYVDD AHSSGVLGHS GRGTVDHFDL HGRVDFTIGT LSKAIGVVGG 250
    YVAGKKVTID WLKNRGRPFL FSTGMTPSAV GSIIEAIKML MESEEYTDKL 300
    WDNARYFKEK MSVLGFNTGE SETPITPIII GEEAKAIEFS KKLFEAGVFV 350
    SPIVFPTVPK GTGRVRCMVT AGHTKEQLDR AVDAFTKVGK EMNII 395
    Length:395
    Mass (Da):43,149
    Last modified:January 11, 2011 - v1
    Checksum:i25F2F89D54BEF324
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FP565809 Genomic DNA. Translation: CBH21740.1.
    RefSeqiYP_003936645.1. NC_014614.1.

    Genome annotation databases

    EnsemblBacteriaiCBH21740; CBH21740; CLOST_1620.
    GeneIDi9855040.
    KEGGicst:CLOST_1620.
    PATRICi42273876. VBICloSti32817_1608.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FP565809 Genomic DNA. Translation: CBH21740.1 .
    RefSeqi YP_003936645.1. NC_014614.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CBH21740 ; CBH21740 ; CLOST_1620 .
    GeneIDi 9855040.
    KEGGi cst:CLOST_1620.
    PATRICi 42273876. VBICloSti32817_1608.

    Phylogenomic databases

    HOGENOMi HOG000221022.
    KOi K00639.
    OMAi FNCNAGT.

    Enzyme and pathway databases

    UniPathwayi UPA00078 .
    BioCyci CSTI499177:GJE9-1674-MONOMER.

    Family and domain databases

    Gene3Di 3.40.640.10. 1 hit.
    3.90.1150.10. 1 hit.
    InterProi IPR001917. Aminotrans_II_pyridoxalP_BS.
    IPR004839. Aminotransferase_I/II.
    IPR010962. AONS_Archaea/Firmicutes.
    IPR004723. AONS_Archaea/Proteobacteria.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    IPR015422. PyrdxlP-dep_Trfase_major_sub2.
    [Graphical view ]
    Pfami PF00155. Aminotran_1_2. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53383. SSF53383. 1 hit.
    TIGRFAMsi TIGR00858. bioF. 1 hit.
    TIGR01825. gly_Cac_T_rel. 1 hit.
    PROSITEi PS00599. AA_TRANSFER_CLASS_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Clostridium sticklandii, a specialist in amino acid degradation:revisiting its metabolism through its genome sequence."
      Fonknechten N., Chaussonnerie S., Tricot S., Lajus A., Andreesen J.R., Perchat N., Pelletier E., Gouyvenoux M., Barbe V., Salanoubat M., Le Paslier D., Weissenbach J., Cohen G.N., Kreimeyer A.
      BMC Genomics 11:555-555(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 12662 / DSM 519 / JCM 1433 / NCIB 10654Imported.

    Entry informationi

    Entry nameiE3PS86_CLOSD
    AccessioniPrimary (citable) accession number: E3PS86
    Entry historyi
    Integrated into UniProtKB/TrEMBL: January 11, 2011
    Last sequence update: January 11, 2011
    Last modified: October 1, 2014
    This is version 22 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3