E3PJ90 (ACFD_ECOH1) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative lipoprotein AcfD homolog

Gene names

Name:	yghJ
Ordered Locus Names:	ETEC_3241

Organism

Escherichia coli O78:H11 (strain H10407 / ETEC) [Complete proteome] [HAMAP]

Taxonomic identifier

316401 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli

Protein attributes

Sequence length	1519 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Predicted

General annotation (Comments)

Subcellular location	Cell membrane; Lipid-anchor Potential.
Sequence similarities	To V.cholerae AcfD (VC_0845).

Ontologies

Keywords
Cellular component	Cell membrane Membrane
Domain	Signal
PTM	Lipoprotein Palmitate
Technical term	Complete proteome
Gene Ontology (GO)
Cellular_component	plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 23	23	Potential
	Chain	24 – 1519	1496	Putative lipoprotein AcfD homolog		PRO_0000405305
Amino acid modifications
	Lipidation	24	1	N-palmitoyl cysteine Potential
	Lipidation	24	1	S-diacylglycerol cysteine Potential

Sequences

	Sequence		Length	Mass (Da)
	E3PJ90 [UniParc]. Last modified January 11, 2011. Version 1. Checksum: 402DB4A166EE2165	FASTA	1,519	168,014
	10 20 30 40 50 60 MNKKFKYKKS LLAAILSATL LAGCDGGGSG SSSDTPPVDS GTGSLPEVKP DPTPNPEPTP 70 80 90 100 110 120 EPTPDPEPTP EPIPDPEPTP EPEPEPVPTK TGYLTLGGSQ RVTGATCNGE SSDGFTFKPG 130 140 150 160 170 180 EDVTCVAGNT TIATFNTQSE AARSLRAVEK VSFSLEDAQE LAGSDDKKSN AVSLVTSSNS 190 200 210 220 230 240 CPANTEQVCL TFSSVIESKR FDSLYKQIDL APEEFKKLVN EEVENNAATD KAPSTHTSPV 250 260 270 280 290 300 VPVTTPGTKP DLNASFVSAN AEQFYQYQPT EIILSEGRLV DSQGYGVAGV NYYTNSGRGV 310 320 330 340 350 360 TGENGEFSFS WGEAISFGID TFELGSVRGN KSTIALTELG DEVRGANIDQ LIHRYSTTGQ 370 380 390 400 410 420 NNTRVVPDDV RKVFAEYPNV INEIINLSLS NGATLGEGEQ VVNLPNEFIE QFNTGQAKEI 430 440 450 460 470 480 DTAICAKTDG CNEARWFSLT TRNVNDGQIQ GVINKLWGVD TNYKSVSKFH VFHDSTNFYG 490 500 510 520 530 540 STGNARGQAV VNISNAAFPI LMARNDKNYW LAFGEKRAWD KNELAYITEA PSIVRPENVT 550 560 570 580 590 600 RETASFNLPF ISLGQVGDGK LMVIGNPHYN SILRCPNGYS WNGGVNKDGQ CTLNSDPDDM 610 620 630 640 650 660 KNFMENVLRY LSNDRWLPDA KSSMTVGTNL ETVYFKKHGQ VLGNSAPFAF HKDFTGITVK 670 680 690 700 710 720 PMTSYGNLNP DEVPLLILNG FEYVTQWGSD PYSIPLRADT SKPKLTQQDV TDLIAYMNKG 730 740 750 760 770 780 GSVLIMENVM SNLKEESASG FVRLLDAAGL SMALNKSVVN NDPQGYPDRV RQRRSTPIWV 790 800 810 820 830 840 YERYPAVDGK PPYTIDDTTK EVIWKYQQEN KPDDKPKLEV ASWQEEVEGK QVTQFAFIDE 850 860 870 880 890 900 ADHKTPESLA AAKQRILDAF PGLEVCKDSD YHYEVNCLEY RPGTDVPVTG GMYVPQYTQL 910 920 930 940 950 960 DLSADTAKAM LQAADLGTNI QRLYQHELYF RTNGRQGERL NSVDLERLYQ NMSVWLWNET 970 980 990 1000 1010 1020 KYRYEEGKED ELGFKTFTEF LNCYTNNAYV GTQCSAELKK SLIDNKMIYG EESSKAGMMN 1030 1040 1050 1060 1070 1080 PSYPLNYMEK PLTRLMLGRS WWDLNIKVDV EKYPGVVNTN GETVTQNINL YSAPTKWFAG 1090 1100 1110 1120 1130 1140 NMQSTGLWAP AQQEVSIESK STVPVTVTVA LADDLTGREK HEVSLNRPPR VTKTYDLKAN 1150 1160 1170 1180 1190 1200 DKVTFKVPYG GLIYIKGDSK EVQSADFTFT GVVKAPFYKD GKWQHDLNSP APLGELESAS 1210 1220 1230 1240 1250 1260 FVYTTPKKNL NASNYTGGLE QFANDLDTFA SSMNDFYGRD SEDGKHRMFT YKNLPGHKHR 1270 1280 1290 1300 1310 1320 FANDVQISIG DAHSGYPVMN SSFSPNSTTL PTTPLNDWLI WHEVGHNAAE TPLTVPGATE 1330 1340 1350 1360 1370 1380 VANNVLALYM QDRYLGKMNR VADDITVAPE YLEESNGQAW ARGGAGDRLL MYAQLKEWAE 1390 1400 1410 1420 1430 1440 KNFDIKKWYP DGTPLPEFYS EREGMKGWNL FQLMHRKARG DEVSNDKFGG KNYCAESNGN 1450 1460 1470 1480 1490 1500 AADTLMLCAS WVAQTDLSEF FKKWNPGANA YQLPGASEMS FEGGVSQSAY NTLASLDLPK 1510 PEQGPETINQ VTEHKMSAE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"A commensal gone bad: complete genome sequence of the prototypical enterotoxigenic Escherichia coli strain H10407." Crossman L.C., Chaudhuri R.R., Beatson S.A., Wells T.J., Desvaux M., Cunningham A.F., Petty N.K., Mahon V., Brinkley C., Hobman J.L., Savarino S.J., Turner S.M., Pallen M.J., Penn C.W., Parkhill J., Turner A.K., Johnson T.J., Thomson N.R., Smith S.G., Henderson I.R. J. Bacteriol. 192:5822-5831(2010) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: H10407 / ETEC.
[2]	"Identification of a type II protein secretory pathway required for the secretion of heat-labile enterotoxin by enterotoxigenic Escherichia coli." Tauschek M., Gorrell R.J., Strugnell R.A., Robins-Browne R.M. Submitted (SEP-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1320-1519. Strain: H10407 / ETEC.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FN649414 Genomic DNA. Translation: CBJ02741.1. AY056599 Genomic DNA. Translation: AAL10688.1.
RefSeq	YP_006116782.1. NC_017633.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CBJ02741; CBJ02741; ETEC_3241.
GeneID	12879606.
KEGG	elh:ETEC_3241.
PATRIC	42962667. VBIEscCol136115_3679.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000124914.
KO	K10939.
Gene expression databases
Genevestigator	Q46837.
Family and domain databases
InterPro	IPR025385. DUF4092. [Graphical view]
Pfam	PF13322. DUF4092. 1 hit. [Graphical view]
PROSITE	PS51257. PROKAR_LIPOPROTEIN. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACFD_ECOH1

Accession

Primary (citable) accession number: E3PJ90
Secondary accession number(s): Q2M9M2 , Q46837, Q46838, Q6BF58

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 8, 2011
Last sequence update:	January 11, 2011
Last modified:	May 1, 2013
This is version 15 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program