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Protein
Submitted name:

KIR2DL3

Gene

KIR2DL3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

Keywordsi

Molecular functionReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
KIR2DL3Imported
Submitted name:
Killer cell immunoglobulin-like receptor two domains long cytoplasmic tail 3Imported
Gene namesi
Name:KIR2DL3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei244 – 265HelicalSequence analysisAdd BLAST22

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_501011359822 – 341Sequence analysisAdd BLAST320

Expressioni

Gene expression databases

ExpressionAtlasiE3NZD8. baseline and differential.

Structurei

3D structure databases

SMRiE3NZD8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini34 – 114IGInterPro annotationAdd BLAST81
Domaini134 – 221IGInterPro annotationAdd BLAST88

Keywords - Domaini

Immunoglobulin domainSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

KOiK07981.
OMAiDARESWL.
OrthoDBiEOG091G0APE.

Family and domain databases

Gene3Di2.60.40.10. 2 hits.
InterProiView protein in InterPro
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR013151. Immunoglobulin.
PfamiView protein in Pfam
PF00047. ig. 2 hits.
SMARTiView protein in SMART
SM00409. IG. 2 hits.
SUPFAMiSSF48726. SSF48726. 2 hits.

Sequencei

Sequence statusi: Complete.

E3NZD8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLMVVSMVC VGFFLLQGAW PHEGVHRKPS LLAHPGPLVK SEETVILQCW
60 70 80 90 100
SDVRFQHFLL HREGKFKDTL HLIGEHHDGV SKANFSIGPM MQDLAGTYRC
110 120 130 140 150
YGSVTHSPYQ LSAPSDPLDI VITGLYEKPS LSAQPGPTVL AGESVTLSCS
160 170 180 190 200
SRSSYDMYHL SREGEAHERR FSAGPKVNGT FQADFPLGPA THGGTYRCFG
210 220 230 240 250
SFRDSPYEWS NSSDPLLVSV TGNPSNSWPS PTEPSSETGN PRHLHVLIGT
260 270 280 290 300
SVVIILFILL LFFLLHRWCC NKKNAVVMDQ EPAGNRTVNR EDSDEQDPQE
310 320 330 340
VTYAQLNHCV FTQRKITRPS QRPKTPPTDI IVYTELPNAE P
Length:341
Mass (Da):37,886
Last modified:January 11, 2011 - v1
Checksum:iC21EAFF80EA9AAB2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FJ188693 Genomic DNA. Translation: ADN34702.1.
KC261287 Genomic DNA. Translation: AGG79413.1.
KC261292 Genomic DNA. Translation: AGG79418.1.
KC261293 Genomic DNA. Translation: AGG79419.1.
KP420438 Genomic DNA. Translation: AJI80989.1.
KP420439 Genomic DNA. Translation: AJI80994.1.
KP420443 Genomic DNA. Translation: AJI81025.1.
KP420445 Genomic DNA. Translation: AJI81035.1.
KU645196 Genomic DNA. Translation: ANJ04789.1.
KU645197 Genomic DNA. Translation: ANJ04801.1.
RefSeqiNP_056952.2. NM_015868.2.
UniGeneiHs.654608.
Hs.731378.

Genome annotation databases

GeneIDi3804.
KEGGihsa:3804.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiE3NZD8_HUMAN
AccessioniPrimary (citable) accession number: E3NZD8
Entry historyiIntegrated into UniProtKB/TrEMBL: January 11, 2011
Last sequence update: January 11, 2011
Last modified: July 5, 2017
This is version 57 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.