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Protein

Beta-hexosaminidase

Gene

Cre-hex-1

Organism
Caenorhabditis remanei (Caenorhabditis vulgaris)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei337Proton donorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidaseUniRule annotation, Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-hexosaminidaseUniRule annotation (EC:3.2.1.52UniRule annotation)
Gene namesi
Name:Cre-hex-1Imported
ORF Names:CRE_00469Imported
OrganismiCaenorhabditis remanei (Caenorhabditis vulgaris)Imported
Taxonomic identifieri31234 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000008281 Componenti: Unassembled WGS sequence

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 15Sequence analysisAdd BLAST15
ChainiPRO_501267770916 – 567Beta-hexosaminidaseSequence analysisAdd BLAST552

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi62 ↔ 102UniRule annotation
Disulfide bondi275 ↔ 345UniRule annotation
Disulfide bondi535 ↔ 553UniRule annotation

Keywords - PTMi

Disulfide bondUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi31234.CRE00469

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini90 – 144Glycohydro_20b2InterPro annotationAdd BLAST55
Domaini167 – 516Glyco_hydro_20InterPro annotationAdd BLAST350

Sequence similaritiesi

Belongs to the glycosyl hydrolase 20 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG2499 Eukaryota
COG3525 LUCA
InParanoidiE3LD00
OMAiFAPWAHA
OrthoDBiEOG091G04NA

Family and domain databases

Gene3Di3.30.379.10, 1 hit
InterProiView protein in InterPro
IPR025705 Beta_hexosaminidase_sua/sub
IPR015883 Glyco_hydro_20_cat
IPR017853 Glycoside_hydrolase_SF
IPR029018 Hex-like_dom2
IPR029019 HEX_eukaryotic_N
PfamiView protein in Pfam
PF00728 Glyco_hydro_20, 1 hit
PF14845 Glycohydro_20b2, 1 hit
PIRSFiPIRSF001093 B-hxosamndse_ab_euk_, 1 hit
PRINTSiPR00738 GLHYDRLASE20
SUPFAMiSSF51445 SSF51445, 1 hit
SSF55545 SSF55545, 1 hit

Sequencei

Sequence statusi: Complete.

E3LD00-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRLLILSLLF VSTFAWFYGR DEPDRWSVGG VWPLPQKIIY GSKNRTLTYD
60 70 80 90 100
KIGIDLGDRK DCDVLLSMAD NYMNKWLFPY PVEMKTGGTE DFIITVTVKE
110 120 130 140 150
ECPSGPPVHG ASEEYLLRVS LSEAVINAQT VWGALRAMES LSHLVFYDQK
160 170 180 190 200
SQEYKIRTVE IFDKPRFPVR GIMIDTSRHF LSLNVIKRQL EIMSMNKMNV
210 220 230 240 250
LHWHLVDSES FPYTSEKFPE LHGVGAYSPR HVYSREDIAE VIAFARLRGI
260 270 280 290 300
RVIPEFDLPG HTSSWKGRKG FLTECFDEKG EETFLPNLVD PMNEANFDFI
310 320 330 340 350
SVSENVNRKT FNLLVQEFLE EVTETFPDQF LHLGGDEVND FIVECWVRNK
360 370 380 390 400
KIRKFMEEKG FGNDTILLEN YFFEKLFAIV EKLKLKRKPI FWQEVFDNNI
410 420 430 440 450
PDPNSIIHIW KGNTHEEIYE QVKNITSKNF PVIISACWYL NYIKYGADWR
460 470 480 490 500
DEISGTAPSN SRYYYCDPTN FNGTDAQKNL VLGGIAAIWG ELVDNTNIEA
510 520 530 540 550
RLWPRASAAA ERLWSPAEKT QRAEDAWPRM HELRCRLVSR GYRIQPNNNP
560
DFCPFEFDEP PATKSEL
Length:567
Mass (Da):65,797
Last modified:January 11, 2011 - v1
Checksum:iDAE786580C87DC61
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS268407 Genomic DNA Translation: EFO83073.1
RefSeqiXP_003118475.1, XM_003118427.1

Genome annotation databases

EnsemblMetazoaiCRE00469; CRE00469; WBGene00052093
GeneIDi9824382

Similar proteinsi

Entry informationi

Entry nameiE3LD00_CAERE
AccessioniPrimary (citable) accession number: E3LD00
Entry historyiIntegrated into UniProtKB/TrEMBL: January 11, 2011
Last sequence update: January 11, 2011
Last modified: March 28, 2018
This is version 45 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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