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Protein

DNA ligase

Gene

PGTG_12168

Organism
Puccinia graminis f. sp. tritici (strain CRL 75-36-700-3 / race SCCL) (Black stem rust fungus)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. base-excision repair Source: EnsemblFungi
  2. DNA biosynthetic process Source: InterPro
  3. DNA ligation involved in DNA repair Source: InterPro
  4. DNA recombination Source: UniProtKB-KW
  5. maintenance of DNA trinucleotide repeats Source: EnsemblFungi
  6. nucleotide-excision repair Source: EnsemblFungi
  7. Okazaki fragment processing involved in mitotic DNA replication Source: EnsemblFungi
  8. telomere maintenance Source: EnsemblFungi
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotationImported

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:PGTG_12168Imported
OrganismiPuccinia graminis f. sp. tritici (strain CRL 75-36-700-3 / race SCCL) (Black stem rust fungus)Imported
Taxonomic identifieri418459 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaBasidiomycotaPucciniomycotinaPucciniomycetesPuccinialesPucciniaceaePuccinia
ProteomesiUP000008783 Componenti: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

  1. mitochondrion Source: EnsemblFungi
  2. nucleus Source: EnsemblFungi
Complete GO annotation...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

InParanoidiE3KPH7.
KOiK10747.
OrthoDBiEOG7TXKRG.

Family and domain databases

Gene3Di1.10.3260.10. 2 hits.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 2 hits.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E3KPH7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGAPASSSSN SNGPTKQATL NKFFSKPAGH KPALVQATVN SLFNKQNRKK
60 70 80 90 100
SEEKEEDTGQ GHVSRDLKRA PSIDVEEHEN PARSSKRAKS NQTKKAEEND
110 120 130 140 150
DDKDAIKATE EPREEPKPTK KISKKQSKTK VEEAEELNEL KVSNEPIQKK
160 170 180 190 200
ETPVIQQEEH TDEDEEAEEL AILDCGDDMN QQEGGVSWEK GKPIPYSSLA
210 220 230 240 250
YTFNLIDGTT KRLEITKYLT QYLIQVISRT PDELLKVIYL CINRLCPDYE
260 270 280 290 300
GIELGIGESL LIKAIGSFHG VAQIVDHSKD YSQAKKVGII TKLLASCQGE
310 320 330 340 350
EAKFIIRSLE GKLRIGLAER TVLVALANAA VRTGVGNKSN SKRKSSSEDL
360 370 380 390 400
AKDILEGTEI VKAVFSEIPS YDLVIPALLQ GGIKGLRENC KLTPGVPLKP
410 420 430 440 450
MLAKPTKAIS EVLDRFEGHK FTCEYKYDGE RAQIHFLSDG SISIFSRNSE
460 470 480 490 500
NMSVKYPDMV DQLPRAIKKD VTRNFVLDAE AVAWDRSTKK ILPFQELSKR
510 520 530 540 550
KRKDVKAEEI TIQVHIFAFD LLYLNDQPLI NTDFSHRRSL LKEHFNQIEG
560 570 580 590 600
EFSFATAVDV DNVEEIQTFL EQSVKAGCEG LMVKMLDGQS AHYEPSRRSM
610 620 630 640 650
NWLKVKKDYL AGIGDSLDLV VVGAYHGKGK RTAVYGAFLL ACYDPETESY
660 670 680 690 700
QTICKLGTGF SEEVLDCLHT KLHPLELTVK KNYYDVGESK PDVWFEPKLV
710 720 730 740 750
WEVLAADLSL SPVYSAAKGL CGDGTRGVSL RFPRYIKERD DKNGEDATSS
760 770 780
EQVAEMYKKQ ASTVDQAGAR NKKKKGKAGQ DDIEDDFW
Length:788
Mass (Da):88,019
Last modified:April 17, 2012 - v2
Checksum:i7B4FD3072CBC5654
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS178299 Genomic DNA. Translation: EFP86212.2.
RefSeqiXP_003330631.2. XM_003330583.2.

Genome annotation databases

EnsemblFungiiEFP86212; EFP86212; PGTG_12168.
GeneIDi10540222.
KEGGipgr:PGTG_12168.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS178299 Genomic DNA. Translation: EFP86212.2.
RefSeqiXP_003330631.2. XM_003330583.2.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiEFP86212; EFP86212; PGTG_12168.
GeneIDi10540222.
KEGGipgr:PGTG_12168.

Phylogenomic databases

InParanoidiE3KPH7.
KOiK10747.
OrthoDBiEOG7TXKRG.

Family and domain databases

Gene3Di1.10.3260.10. 2 hits.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 2 hits.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: CRL 75-36-700-3.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CRL 75-36-700-3 / race SCCLImported.

Entry informationi

Entry nameiE3KPH7_PUCGT
AccessioniPrimary (citable) accession number: E3KPH7
Entry historyi
Integrated into UniProtKB/TrEMBL: January 10, 2011
Last sequence update: April 17, 2012
Last modified: March 31, 2015
This is version 23 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.