E3J0E1 (PHNN_FRASU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribose 1,5-bisphosphate phosphokinase PhnN
EC=2.7.4.23

Alternative name(s):
Ribose 1,5-bisphosphokinase

Gene names

Name:	phnN
Ordered Locus Names:	FraEuI1c_3563

Organism

Frankia sp. (strain EuI1c) [Complete proteome] [HAMAP]

Taxonomic identifier

298654 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Frankineae › Frankiaceae › Frankia

Protein attributes

Sequence length	190 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) By similarity. HAMAP-Rule MF_00836
Catalytic activity	ATP + alpha-D-ribose 1,5-bisphosphate = ADP + 5-phospho-alpha-D-ribose 1-diphosphate. HAMAP-Rule MF_00836
Pathway	Metabolic intermediate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route II): step 3/3. HAMAP-Rule MF_00836
Sequence similarities	Belongs to the ribose 1,5-bisphosphokinase family.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	5-phosphoribose 1-diphosphate biosynthetic process Inferred from electronic annotation. Source: HAMAP organic phosphonate metabolic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ribose 1,5-bisphosphate phosphokinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 190	190	Ribose 1,5-bisphosphate phosphokinase PhnN HAMAP-Rule MF_00836		PRO_0000412786

Sequences

	Sequence		Length	Mass (Da)
	E3J0E1 [UniParc]. Last modified January 11, 2011. Version 1. Checksum: 3416DC1624487BF0	FASTA	190	20,107
	10 20 30 40 50 60 MTERIGPGAF VAVVGASGVG KDALMAYARE RSEAVAHFPR RVITRPSGPG EDHEPVTEEQ 70 80 90 100 110 120 FTAARERGEL AVWWPAHGLR YGIPASADVA VGAGRVVVAN VSRAVLDELA GRYQRLVVVR 130 140 150 160 170 180 VTVSDEVRAQ RLRARGREPE PGIGQRLARP DPAPGHQADT VIQNDGTLAD GGDQLLRVIL 190 DAAGAPLATG

References

[1]

"Complete sequence of Frankia sp. EuI1c." US DOE Joint Genome Institute Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., Pitluck S., Chertkov O., Detter J.C., Han C., Tapia R., Land M., Hauser L., Jeffries C., Kyrpides N., Ivanova N., Mikhailova N., Beauchemin N. , Sen A., Sur S.A., Gtari M., Wall L., Tisa L., Woyke T. Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: EuI1c.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002299 Genomic DNA. Translation: ADP81570.1.
RefSeq	YP_004017440.1. NC_014666.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADP81570; ADP81570; FraEuI1c_3563.
GeneID	9974002.
KEGG	fri:FraEuI1c_3563.
PATRIC	42619257. VBIFraSp2231_3664.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000037637.
KO	K05774.
Enzyme and pathway databases
BioCyc	FSP298654:GHN6-3596-MONOMER.
UniPathway	UPA00087; UER00175.
Family and domain databases
HAMAP	MF_00836. PhnN.
InterPro	IPR008145. Guanylate_kin/L-typ_Ca_channel. IPR012699. PhnN. [Graphical view]
SMART	SM00072. GuKc. 1 hit. [Graphical view]
TIGRFAMs	TIGR02322. phosphon_PhnN. 1 hit.
PROSITE	PS50052. GUANYLATE_KINASE_2. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PHNN_FRASU

Accession

Primary (citable) accession number: E3J0E1

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 21, 2011
Last sequence update:	January 11, 2011
Last modified:	May 1, 2013
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program