ID   E3IZR2_PSEI1            Unreviewed;       487 AA.
AC   E3IZR2;
DT   11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT   11-JAN-2011, sequence version 1.
DT   27-MAR-2024, entry version 56.
DE   SubName: Full=Aldehyde Dehydrogenase {ECO:0000313|EMBL:ADP83980.1};
GN   OrderedLocusNames=FraEuI1c_5996 {ECO:0000313|EMBL:ADP83980.1};
OS   Pseudofrankia inefficax (strain DSM 45817 / CECT 9037 / DDB 130130 / EuI1c)
OS   (Frankia inefficax).
OC   Bacteria; Actinomycetota; Actinomycetes; Frankiales; Frankiaceae;
OC   Pseudofrankia.
OX   NCBI_TaxID=298654 {ECO:0000313|EMBL:ADP83980.1, ECO:0000313|Proteomes:UP000002484};
RN   [1] {ECO:0000313|EMBL:ADP83980.1, ECO:0000313|Proteomes:UP000002484}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 45817 / CECT 9037 / EuI1c
RC   {ECO:0000313|Proteomes:UP000002484};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA   Pitluck S., Chertkov O., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA   Jeffries C., Kyrpides N., Ivanova N., Mikhailova N., Beauchemin N., Sen A.,
RA   Sur S.A., Gtari M., Wall L., Tisa L., Woyke T.;
RT   "Complete sequence of Frankia sp. EuI1c.";
RL   Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC       {ECO:0000256|RuleBase:RU003345}.
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DR   EMBL; CP002299; ADP83980.1; -; Genomic_DNA.
DR   RefSeq; WP_013427098.1; NC_014666.1.
DR   AlphaFoldDB; E3IZR2; -.
DR   STRING; 298654.FraEuI1c_5996; -.
DR   KEGG; fri:FraEuI1c_5996; -.
DR   eggNOG; COG1012; Bacteria.
DR   HOGENOM; CLU_005391_0_0_11; -.
DR   InParanoid; E3IZR2; -.
DR   OrthoDB; 6882680at2; -.
DR   Proteomes; UP000002484; Chromosome.
DR   GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   InterPro; IPR016161; Ald_DH/histidinol_DH.
DR   InterPro; IPR016163; Ald_DH_C.
DR   InterPro; IPR029510; Ald_DH_CS_GLU.
DR   InterPro; IPR016162; Ald_DH_N.
DR   InterPro; IPR015590; Aldehyde_DH_dom.
DR   PANTHER; PTHR11699:SF211; ALDEHYDE DEHYDROGENASE FAMILY 16 MEMBER A1; 1.
DR   PANTHER; PTHR11699; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR   Pfam; PF00171; Aldedh; 1.
DR   SUPFAM; SSF53720; ALDH-like; 1.
DR   PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000256|RuleBase:RU003345};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002484}.
FT   DOMAIN          28..484
FT                   /note="Aldehyde dehydrogenase"
FT                   /evidence="ECO:0000259|Pfam:PF00171"
FT   ACT_SITE        257
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ   SEQUENCE   487 AA;  51578 MW;  2A7BCBD5AB0462A2 CRC64;
     MAESGYDRTR PAVHLRIGSE RLAVGSAGTF EHIDPCTGEV DAVVPLAGPS EIDRAVRLAQ
     EAFLVWRDVR PAERRRLLFR LADLIEANAD EFTRRAVLDN GMAVTSASGL VGGATEWTRY
     YAGFADKISG RVNTSFGPDG EFSYTLAQPY GVIGTIITWN GPLTSLTMKV PPALAAGNTV
     VVKPSEMTPF AAELFADLVD EAGFPSGVVS VLPGSVEAGA ALVDHPLVQK ITFTGGPATA
     TAILHACAKQ MKPAVLELGG KSANLVFDDA DLDTAIPWGT LRVLATVSGQ GCAFPTRMLV
     QESIYDETLD RVAALVKGIR VGDPWDTDTD IGPVVNEAAA IRILGMIERA TQDGARLIAG
     GGRPLGLHPG GSFLEPTVFA DVDPHSELGQ SEVFGPVLSI MPFATEEQAI EIANSTRYGL
     SSYIQTKDVR RAHRVAERLE AGATMINGAP NLMVNRPFGG QGYSGYGKEG GPDGLAEFQR
     IKTIAMV
//