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E3IIW7 (E3IIW7_GEOS0) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 21. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Thymidine kinase RuleBase RU000544 HAMAP-Rule MF_00124

EC=2.7.1.21 RuleBase RU000544 HAMAP-Rule MF_00124
Gene names
Name:tdk HAMAP-Rule MF_00124
Ordered Locus Names:GY4MC1_3723 EMBL ADP76348.1
OrganismGeobacillus sp. (strain Y4.1MC1) [Complete proteome] [HAMAP] EMBL ADP76348.1
Taxonomic identifier581103 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeGeobacillus

Protein attributes

Sequence length205 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + thymidine = ADP + thymidine 5'-phosphate. HAMAP-Rule MF_00124 SAAS SAAS020634

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00124 SAAS SAAS020633

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00124 SAAS SAAS020633.

Sequence similarities

Belongs to the thymidine kinase family. HAMAP-Rule MF_00124 RuleBase RU004165

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding15 – 228ATP By similarity HAMAP-Rule MF_00124
Nucleotide binding88 – 914ATP By similarity HAMAP-Rule MF_00124

Sites

Active site891Proton acceptor By similarity HAMAP-Rule MF_00124
Metal binding1451Zinc By similarity HAMAP-Rule MF_00124
Metal binding1481Zinc By similarity HAMAP-Rule MF_00124
Metal binding1831Zinc By similarity HAMAP-Rule MF_00124
Metal binding1861Zinc By similarity HAMAP-Rule MF_00124

Sequences

Sequence LengthMass (Da)Tools
E3IIW7 [UniParc].

Last modified January 11, 2011. Version 1.
Checksum: 5C39744CC92284B6

FASTA20522,863
        10         20         30         40         50         60 
MYVMKQSGWL EVICGSMFSG KSEELIRRVR RATFAKQDVK VFKPTIDNRY SEEAVVSHNG 

        70         80         90        100        110        120 
NSVIAIPVSS PQEIFEHISE KTDVIAIDEV QFFSDDIIEV VQTLADRGYR VIVAGLDQDF 

       130        140        150        160        170        180 
RGEPFGPVPT LMAIAESVTK LQAVCTVCGS PASRTQRLIN GVPASYHDPV ILVGASESYE 

       190        200 
PRCRHHHEVP DKPVKNCQTD NHHVR 

« Hide

References

[1]"Complete sequence of chromosome of Geobacillus sp. Y4.1MC1."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., Pitluck S., Chertkov O., Zhang X., Detter J.C., Han C., Tapia R., Land M., Hauser L., Jeffries C., Kyrpides N., Ivanova N., Ovchinnikova G. expand/collapse author list , Brumm P., Mead D., Woyke T.
Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Y4.1MC1 EMBL ADP76348.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002293 Genomic DNA. Translation: ADP76348.1.
RefSeqYP_003990959.1. NC_014650.1.

3D structure databases

ProteinModelPortalE3IIW7.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADP76348; ADP76348; GY4MC1_3723.
GeneID9930647.
KEGGgmc:GY4MC1_3723.
PATRIC42638042. VBIGeoSp111282_4102.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000076390.
KOK00857.
OMAELICGSM.

Enzyme and pathway databases

BioCycGSP581103:GHT2-3841-MONOMER.

Family and domain databases

HAMAPMF_00124. Thymidine_kinase.
InterProIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERPTHR11441. PTHR11441. 1 hit.
PfamPF00265. TK. 1 hit.
[Graphical view]
PIRSFPIRSF035805. TK_cell. 1 hit.
SUPFAMSSF52540. SSF52540. 1 hit.
PROSITEPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameE3IIW7_GEOS0
AccessionPrimary (citable) accession number: E3IIW7
Entry history
Integrated into UniProtKB/TrEMBL: January 11, 2011
Last sequence update: January 11, 2011
Last modified: April 16, 2014
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)