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E3I2D7 (E3I2D7_RHOVT) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length384 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201 SAAS SAAS020622

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS020622

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. RuleBase RU004188 HAMAP-Rule MF_01201

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site521Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2721Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1501Substrate By similarity HAMAP-Rule MF_01201
Binding site3251Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue521N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
E3I2D7 [UniParc].

Last modified January 11, 2011. Version 1.
Checksum: 421D2C1868280A01

FASTA38441,772
        10         20         30         40         50         60 
MDTGFSEAVE RALAAAPASA NGVLVIRLPA LRRNYRRAAE ASLKAETAAV VKANAYGLGI 

        70         80         90        100        110        120 
QPVLTALQKE TARTFFVATL DEALALRTFA NDATIYTLNG LMPGTSAVYR DARLRPVLNS 

       130        140        150        160        170        180 
LAEVEEWSAY CREHEARLPA AIQFDTGMCR VGLEPEAADA LAEKPELLQP FRPAVLMSHL 

       190        200        210        220        230        240 
VRADEPMHPL NEVQFKRFEA VTSLFPGIAK SLVNSAGCLL RRKYHLDLAR PGIAIYGGNP 

       250        260        270        280        290        300 
QKVEPSQFEP VVWLFGRIVQ VRHGEKGFTV GYGGTETLRR DSRIATVGVG YADGYFRGVS 

       310        320        330        340        350        360 
SSDAKPGAVG HIGEHALPLI GRVSMDLTTF DATDVPEALV HRGGFVELLG EKTTVDDLAR 

       370        380 
HAGTIGYEVL TSLGRRYHRV YVDE 

« Hide

References

[1]"Genome sequences of eight morphologically diverse alphaproteobacteria."
US DOE Joint Genome Institute
Brown P.J., Kysela D.T., Buechlein A., Hemmerich C., Brun Y.V.
J. Bacteriol. 193:4567-4568(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 17100 / ATH 3.1.1 / DSM 162 / LMG 4299.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002292 Genomic DNA. Translation: ADP70221.1.
RefSeqYP_004011320.1. NC_014664.1.

3D structure databases

ProteinModelPortalE3I2D7.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADP70221; ADP70221; Rvan_0945.
GeneID9931723.
KEGGrva:Rvan_0945.
PATRIC42669016. VBIRhoVan113057_1001.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000031445.
KOK01775.

Enzyme and pathway databases

BioCycRVAN648757:GHZT-959-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameE3I2D7_RHOVT
AccessionPrimary (citable) accession number: E3I2D7
Entry history
Integrated into UniProtKB/TrEMBL: January 11, 2011
Last sequence update: January 11, 2011
Last modified: July 9, 2014
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)